scholarly journals Detecting disease rare alleles using single SNPs in families and haplotyping in unrelated subjects from the Genetic Analysis Workshop 17 data

2011 ◽  
Vol 5 (S9) ◽  
Author(s):  
Aldi T Kraja ◽  
Jacek Czajkowski ◽  
Mary F Feitosa ◽  
Ingrid B Borecki ◽  
Michael A Province
1985 ◽  
Vol 2 (2) ◽  
pp. 219-220
Author(s):  
R. Arlen Price ◽  
Patricia L. Kramer ◽  
Andrew J. Pakstis ◽  
Kenneth K. Kidd

2018 ◽  
Vol 12 (S9) ◽  
Author(s):  
Aldi T. Kraja ◽  
Ping An ◽  
Petra Lenzini ◽  
Shiou J. Lin ◽  
Christine Williams ◽  
...  

2011 ◽  
Vol 72 (2) ◽  
pp. 115-119 ◽  
Author(s):  
Leon Mejnartowicz

Twenty-eight isozymic loci were studied in the Beskid Mts., in four populations of common silver-fir (<em>Abies alba</em>): one in Beskid Makowski (BM) and three populations in Beskid Sądecki (BS). Their genetic variation and diversity were analyzed, and Nei's genetic distances between the populations were calculated. The results show that the geographical distance between the BM population and the three BS populations is reflected in genetic distances. The BM population is clearly distinct from the others. It has the lowest genetic diversity (<em>I</em> = <em>0.42</em>), percentage of polymorphic loci <em>(%PoL </em>= <em>64.29</em>) and number of rare alleles (<em>NoRa </em>= <em>5</em>). Besides, the BM population has the highest observed heterozygosity (<em>Ho </em>= <em>0.291</em>), which exceeds the expected heterozygosity (<em>He </em>= <em>0.254</em>), estimated on the basis of the Hardy-Weinberg Principle. On the contrary, BS populations are in the state of equilibrium, which is manifested, in similar values of <em>He </em>= <em>0.262 </em>and <em>Ho </em>= <em>0.264</em>.


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