scholarly journals Characterization of the tumor marker muc16 (CA125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies

2009 ◽  
Vol 2 (1) ◽  
pp. 8 ◽  
Author(s):  
Cara A.R. Goodell ◽  
Jennifer A Belisle ◽  
Jennifer A.A. Gubbels ◽  
Martine Migneault ◽  
Claudine Rancourt ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Tumor Cell ◽  
Tumor Marker ◽  
Cell Lines ◽  
Ovarian Tumor ◽  
Tumor Cell Lines ◽  
Ovarian Tumor Cell

A lack of significant modulation of the formation and removal of platinum-DNA adducts in logarithmically growing human ovarian tumor cell lines in vitro by aphidicolin addition

1990 ◽  
Vol 17 ◽  
pp. 92-93
Author(s):  
Wolfram C.M. Dempke∗ ◽  
Sharon A. Shellard∗ ◽  
Anne Marie J. Fichtinger-Schepman† ◽  
Bridget T. Hill∗
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Dna Adducts ◽  
Ovarian Tumor ◽  
Tumor Cell Lines ◽  
Ovarian Tumor Cell

Production and Characterization of two Monoclonal Antibodies Directed against the Integrin β1 Chain

1992 ◽  
Vol 78 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Rita Pellegrini ◽  
Paola Bazzini ◽  
Emanuela Tosi ◽  
Elda Tagliabue ◽  
Grazia Conforti ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Monoclonal Antibodies ◽  
Tumor Cell ◽  
Tumor Cells ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
Integrin Β1 ◽  
Α Subunits ◽  
Cross Competition

The production and characterization of two new monoclonal antibodies (MAbs), designated MAR4 and MAR5, raised against the partially purified α5β1 integrin, are described. The reactivity of these 2 MAbs on tumor cell lines indicated that they reacted on all the cells expressing the β1 subunit independently of the α5 expression. Both MAbs were found to immunoprecipitate on 3 cell lines, a protein of 120 KD corresponding to the molecular weight be the β1 chain, in addition to proteins of other MW corresponding to the α subunits differentially expressed by these cells. The cross-competition experiments showed that MAR4 and MAR5 recognize the same epitope. These 2 MAbs seem to be useful reagents for the characterization of the VLA expression in tumor cells.

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