Characterization of the trigeminovascular actions of several adenosine A2A receptor antagonists in an in vivo rat model of migraine

A2a Receptor ◽

Adenosine A2A receptor antagonists improve deficits in initiation of movement and sensory motor integration in the unilateral 6-hydroxydopamine rat model of Parkinson's disease

Synapse ◽

10.1002/syn.20410 ◽

2007 ◽

Vol 61 (8) ◽

pp. 606-614 ◽

Cited By ~ 62

Author(s):

Annalisa Pinna ◽

Silvia Pontis ◽

Franco Borsini ◽

Micaela Morelli

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Rat Model ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

A2a Receptor ◽

Sensory Motor ◽

6 Hydroxydopamine ◽

A Meta-Analysis of Adenosine A2A Receptor Antagonists on Levodopa-Induced Dyskinesia In Vivo

Frontiers in Neurology ◽

10.3389/fneur.2017.00702 ◽

2017 ◽

Vol 8 ◽

Cited By ~ 4

Author(s):

Wen-Wen Wang ◽

Man-Man Zhang ◽

Xing-Ru Zhang ◽

Zeng-Rui Zhang ◽

Jie Chen ◽

...

Keyword(s):

Meta Analysis ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

A2a Receptor ◽

Characterization of the potency, selectivity, and pharmacokinetic profile for six adenosine A2A receptor antagonists

Naunyn-Schmiedeberg s Archives of Pharmacology ◽

10.1007/s00210-007-0135-0 ◽

2007 ◽

Vol 375 (2) ◽

pp. 133-144 ◽

Cited By ~ 55

Author(s):

Ming Yang ◽

Daniel Soohoo ◽

Sandriyana Soelaiman ◽

Rao Kalla ◽

Jeff Zablocki ◽

...

Keyword(s):

Pharmacokinetic Profile ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

A2a Receptor ◽

Adenosine A2A Receptor Antagonists in Parkinson’s Disease: Progress in Clinical Trials from the Newly Approved Istradefylline to Drugs in Early Development and Those Already Discontinued

CNS Drugs ◽

10.1007/s40263-014-0161-7 ◽

2014 ◽

Vol 28 (5) ◽

pp. 455-474 ◽

Cited By ~ 115

Author(s):

Annalisa Pinna

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Clinical Trials ◽

Early Development ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Disease Progress ◽

A2a Receptor ◽

The Controversial Role of Adenosine A2A Receptor Antagonists as Neuro-protective Agents

Current Medicinal Chemistry - Central Nervous System Agents ◽

10.2174/1568015043477577 ◽

2004 ◽

Vol 4 (1) ◽

pp. 35-45 ◽

Cited By ~ 6

Author(s):

Patrizia Popoli ◽

David Blum ◽

Annita Pintor ◽

Maria Tebano ◽

Claudio Frank ◽

...

Keyword(s):

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Protective Agents ◽

A2a Receptor ◽

Hit-to-lead optimization of a series of carboxamides of ethyl 2-amino-4-phenylthiazole-5-carboxylates as novel adenosine A2A receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2010.06.138 ◽

2010 ◽

Vol 20 (17) ◽

pp. 5241-5244 ◽

Cited By ~ 7

Author(s):

Anette Graven Sams ◽

Gitte Kobberøe Mikkelsen ◽

Mogens Larsen ◽

Lars Torup ◽

Lise Tøttrup Brennum ◽

...

Keyword(s):

Adenosine A2a Receptor ◽

Lead Optimization ◽

Receptor Antagonists ◽

A2a Receptor ◽

Synthetic studies on selective adenosine A2A receptor antagonists: Synthesis and structure–activity relationships of novel benzofuran derivatives

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.12.028 ◽

2010 ◽

Vol 20 (3) ◽

pp. 1090-1093 ◽

Cited By ~ 29

Author(s):

Osamu Saku ◽

Mayumi Saki ◽

Masako Kurokawa ◽

Ken Ikeda ◽

Takuya Takizawa ◽

...

Keyword(s):

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Structure Activity Relationships ◽

Structure Activity ◽

A2a Receptor ◽

Synthetic Studies ◽

The effects of adenosine A2A receptor antagonists on haloperidol-induced movement disorders in primates

Psychopharmacology ◽

10.1007/s00213-008-1214-8 ◽

2008 ◽

Vol 200 (3) ◽

pp. 393-401 ◽

Cited By ~ 32

Author(s):

Geoffrey B. Varty ◽

Robert A. Hodgson ◽

Annamarie J. Pond ◽

Michael E. Grzelak ◽

Eric M. Parker ◽

...

Keyword(s):

Movement Disorders ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

A2a Receptor ◽

Use of molecular modeling aided design to dial out hERG liability in adenosine A2A receptor antagonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2015.05.036 ◽

2015 ◽

Vol 25 (15) ◽

pp. 2958-2962 ◽

Cited By ~ 5

Author(s):

Qiaolin Deng ◽

Yeon-Hee Lim ◽

Rajan Anand ◽

Younong Yu ◽

Jae-hun Kim ◽

...

Keyword(s):

Molecular Modeling ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

A2a Receptor ◽

Aided Design ◽

Potential of Adenosine A2A Receptor Antagonists in the Treatment of Movement Disorders

CNS Drugs ◽

10.2165/00023210-199810050-00001 ◽

1998 ◽

Vol 10 (5) ◽

pp. 311-320 ◽

Cited By ~ 21

Author(s):

Judit Mally ◽

Trevor W. Stone

Keyword(s):

Movement Disorders ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

A2a Receptor ◽