scholarly journals Case report: an area postrema syndrome revealing a neuromyelitis optica spectrum disorder associated with central nervous system tuberculosis in a young Togolese (black African) woman

BMC Neurology ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Kossivi Apetse ◽  
Josué Euberma Diatewa ◽  
Jean Joel Dongmo Tajeuna ◽  
Yaovi Mawuéna Dansou ◽  
Rolph Bakoudissa ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Neuromyelitis Optica ◽  
Area Postrema ◽  
Spectrum Disorder ◽  
African Woman ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Black African

Anti‐aquaporin‐4 antibody‐positive neuromyelitis optica spectrum disorder associated with central nervous system tuberculosis

2019 ◽  
Vol 11 (1) ◽  
pp. 40-44
Author(s):  
Enrique Gomez‐Figueroa ◽  
Christian Garcia‐Estrada ◽  
Adriana Casallas-Vanegas ◽  
Indhira Zabala-Angeles ◽  
Ramon Lopez-Martinez ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neuromyelitis Optica ◽  
Spectrum Disorder ◽  
Aquaporin 4 ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Aquaporin 4 Antibody

An uncommon cause of vertigo: Neuromyelitis optica spectrum disorder

2021 ◽  
pp. 014556132110533
Author(s):  
Kuan-Ling Lin ◽  
Ching-Yu Yang ◽  
Wen-Ko Su
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Neuromyelitis Optica ◽  
Spectrum Disorder ◽  
Atypical Presentation ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Positive Serum ◽  
The Central Nervous System ◽  
Aquaporin 4 Antibody

Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon antibody-mediated disease of the central nervous system. Its classic presentation includes long segments of spinal cord inflammation, optic neuritis with or without intractable vomiting, and hiccups. Here, we described a case of a 39-year-old woman with an atypical presentation of vertigo, which was finally diagnosed as NMOSD by a positive serum aquaporin-4 antibody.

Pediatric paraneoplastic neuromyelitis optica spectrum disorder associated with ovarian teratoma

2021 ◽  
pp. 135245852110375
Author(s):  
Lauren Tardo ◽  
Cynthia Wang ◽  
Veena Rajaram ◽  
Benjamin M Greenberg
Keyword(s):  
Central Nervous System ◽  
Pediatric Patient ◽  
Neuromyelitis Optica ◽  
Area Postrema ◽  
Spectrum Disorder ◽  
Aquaporin 4 ◽  
Ovarian Teratoma ◽  
Neuromyelitis Optica Spectrum Disorder ◽  
Inflammatory Condition ◽  
The Central Nervous System

Neuromyelitis optica spectrum disorder is an inflammatory condition of the central nervous system typically manifesting as myelitis, optic neuritis, and/or area postrema syndrome. Here, we present a pediatric patient who developed symptoms consistent with area postrema syndrome with positive anti-aquaporin-4 (AQP4) antibodies who was also found to have an ovarian teratoma. Pathological specimens revealed the presence of aquaporin-4. This was felt to be the antigenic trigger that led to the patient’s condition. She suffered no further clinical attacks and seroconverted to negative AQP4 status upon teratoma removal. This case varies from others, in that the paraneoplastic presentation occurred in a pediatric patient and in that the patient has not required maintenance immunotherapy after teratoma removal.

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