scholarly journals Malignant transformation of pleomorphic xanthoastrocytoma and differential diagnosis: case report

BMC Neurology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Noriyuki Watanabe ◽  
Eiichi Ishikawa ◽  
Hidehiro Kohzuki ◽  
Noriaki Sakamoto ◽  
Alexander Zaboronok ◽  
...  
2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Chintan Malhotra ◽  
Arun K. Jain ◽  
Bikram Thapa

Purpose. Pseudoepitheliomatous hyperplasia at the limbus can mimic an ocular surface squamous neoplasia. It is an uncommon manifestation of vernal keratoconjunctivitis and has been reported previously in limbal VKC. It, however, has not been reported as a manifestation in the palpebral form of the disease and needs to be kept in the differential diagnosis of a limbal mass lesion in vernal keratoconjunctivitis.Case Report. We report the case of a 24 year old male patient having palpebral VKC and presenting with a papillomatous limbal mass with focal areas of keratinization mimicking an ocular surface squamous neoplasia. An excision biopsy was performed, and the specimen sent for histopathologywhich revealed features of pseudoepitheliomatous hyperplasia with no evidence of dysplasia or malignant transformation. The subepithelium revealed a dense plasma-rich inflammation.Discussion. We report this relatively uncommon presentation of limbal pseudoepitheliomatous hyperplasia mimicking an ocular surface squamous neoplasia in palpebral vernal keratoconjunctivitis. Wide excision as is required for an ocular surface neoplasia may thus be avoided if this entity is recognized in vernal keratoconjunctivitis.


2003 ◽  
Vol 61 (1) ◽  
pp. 104-106 ◽  
Author(s):  
Oswaldo Ignácio de Tella Jr ◽  
Marco Antonio Herculano ◽  
Mirto Nelso Prandini ◽  
João Norberto Stavale ◽  
Paulo Henrique Aguiar

We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.


2017 ◽  
Vol 07 (04) ◽  
pp. 376-382
Author(s):  
Oumar Coulibaly ◽  
Mahamadou Dama ◽  
Oumar Diallo ◽  
Q. K. J. Marie Maurin Kisito ◽  
Li Gu ◽  
...  

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