scholarly journals Childhood abuse and borderline personality disorder features in Chinese undergraduates: the role of self-esteem and resilience

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guo-Die Xie ◽  
Jun-Jie Chang ◽  
Meng-Yuan Yuan ◽  
Geng-Fu Wang ◽  
Yang He ◽  
...  

Abstract Background Although childhood abuse is considered to be related to borderline personality disorder (BPD), few studies have elaborated on the mediating role of self-esteem and resilience in it. Thus, the present study aimed to explore the potential mediating role of resilience and self-esteem between childhood abuse and BPD. Methods This cross-sectional study was conducted with 4034 college students in Anhui Province, China. Participants were asked to complete Chinese versions of the following instruments: Childhood Trauma Questionnaire–Short Form (CTQ-SF), Mclean Screening Instrument for Borderline Personality Disorder (MSI-BPD), Connor-Davidson Resilience Scale (CD-RISC), and Rosenberg Self-Esteem Scale (RSES). Structural equation modeling (SEM) was used to test the mediation effects. Results Resilience and self-esteem were found to be mediators of all three types of childhood abuse (emotional abuse, physical abuse and sexual abuse) when the types were examined separately; however, when all three types of childhood abuse were entered into the model simultaneously, neither the indirect effects nor direct effects of physical abuse or sexual abuse were found to be significant, only the association between emotional abuse and BPD features was partially mediated by resilience and self-esteem. Conclusions Self-esteem and resilience mediate the links between childhood abuse and BPD features, and emotional abuse is uniquely associated with BPD features.

2019 ◽  
Author(s):  
Min Zhang ◽  
Na Liu ◽  
Haocheng Chen ◽  
Ning Zhang

Abstract Background Borderline personality disorder (BPD) is caused by a variety of biological and environmental factors. Accumulating evidence suggests that childhood maltreatment is a risk environmental factor in the development of BPD, but research on the genetic pathology of BPD is still in its early stages, and very little is known about the oxytocin receptor (OXTR) gene. The purpose of this study is to further explore the interaction between OXTR gene polymorphism and childhood maltreatment in BPD. Methods A total of 1804 prison inmates and 196 normal controls participated in this study. Childhood maltreatment was measured by a self-reported questionnaire, as was BPD. Venous blood was collected for the genotype test. Results Analyses revealed that the BP group had higher rs53576 AA genotype frequency and rs237987 AA genotype frequency than the non-BP group. Childhood maltreatment and its dimension could positively predict BPD risk. Among the prison samples, rs53576 GG genotype carriers had higher BPD scores at higher levels of emotional abuse, physical abuse and sexual abuse and lower BPD scores at lower levels of physical abuse and sexual abuse. Conclusions The finding suggests that the interaction between childhood maltreatment and OXTR gene variations is an important mechanism for the development of BPD. The moderating role of the OXTR gene provides evidence for gene plasticity.


2006 ◽  
Vol 40 (5) ◽  
pp. 478-481 ◽  
Author(s):  
Stuart Watson ◽  
Roy Chilton ◽  
Helen Fairchild ◽  
Peter Whewell

Objective: To examine the relationship between childhood trauma and dissociative experience in adulthood in patients with borderline personality disorder. Method: Dissociative experiences scale scores and subscale scores for the Childhood Trauma Questionnaire were correlated in 139 patients. Patients were dichotomized into high or low dissociators using the Median Dissociative Experiences Scale score as the cut-off. Results: Childhood Trauma Questionnaire Subscale scores for emotional and physical abuse and emotional neglect but not sexual abuse correlated significantly with Dissociative Experiences Scale scores. High dissociators reported significantly greater levels of emotional abuse, physical abuse, emotional neglect and physical neglect but not sexual abuse than low dissociators. Conclusion: Patients with borderline personality disorder therefore demonstrated levels of dissociation that increased with levels of childhood trauma, supporting the hypothesis that traumatic childhood experiences engender dissociative symptoms later in life. Emotional abuse and neglect may be at least as important as physical and sexual abuse in the development of dissociative symptoms.


2019 ◽  
Author(s):  
Min Zhang ◽  
Na Liu ◽  
Haocheng Chen ◽  
Ning Zhang

Abstract Background: Borderline personality disorder (BPD) is caused by a variety of biological and environmental factors. Accumulating evidence suggests that childhood maltreatment is a risk environmental factor in the development of BPD, but research on the genetic pathology of BPD is still in its early stages, and very little is known about the oxytocin receptor (OXTR) gene. The purpose of this study is to further explore the interactive effects between OXTR gene polymorphisms and childhood maltreatment on BPD risk. Methods: Among the 1804 male inmates, 765 inmates with high risk were included in this study. Childhood maltreatment, BPD, antisocial personality disorder (ASPD) and impulsivity were measured by self-reported questionnaires. Peripheral venous blood was collected for the genotype test. Results: Analyses revealed that the BP group had higher rs53576 AA genotype frequency and rs237987 AA genotype frequency than the non-BP group. Total childhood maltreatment score, emotional abuse and neglect could positively predict BPD risk. Among the high-risk samples, rs53576 GG genotype carriers had higher BPD scores at higher levels of physical abuse and sexual abuse and had lower BPD scores at lower levels of physical abuse and sexual abuse. Conclusions: The findings suggest that the interaction between OXTR gene variations and childhood maltreatment is an important mechanism for the development of BPD. The moderating role of the OXTR gene provides evidence for gene plasticity.


2019 ◽  
Vol 36 ◽  
Author(s):  
Renata SALDANHA-SILVA ◽  
Fabio Luiz NUNES ◽  
Helga Alessandra de REZENDE ◽  
Marcela MANSUR-ALVES

Abstract The present study analyzes the relationship between maladaptive beliefs, personality traits, and Borderline Personality Disorder symptoms by focusing in the mediating role of beliefs in the prediction between personality and psychiatric disorders. The sample consisted of 823 adults aged between 18 and 39 years (M = 24.09, SD = 4.71), who answered a questionnaire of symptoms and beliefs for Borderline Personality Disorder and Big Five Personality Inventory. The predictive model that fit better to the data indicates Neuroticism and Conscientiousness as predictors of Borderline Personality Disorder symptoms, mediated by maladaptive belief patterns. In this sense, it is possible to conclude that both personality traits and maladaptive beliefs are important for the understanding of Borderline Personality Disorder. The theoretical implications of this result and the limitations of the study are discussed.


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