scholarly journals The efficacy of adalimumab in psoriatic arthritis concomitant to overlapping primary biliary cholangitis and primary sclerosing cholangitis: a case report

2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Teresa Del Ross ◽  
Amelia Ruffatti ◽  
Annarosa Floreani ◽  
Ariela Hoxha ◽  
Leonardo Punzi
Keyword(s):  
Case Report ◽  
Psoriatic Arthritis ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Primary Biliary Cholangitis

Primary biliary cholangitis–primary sclerosing cholangitis in an evolving overlap syndrome: A case report

2017 ◽  
Vol 40 (10) ◽  
pp. 669-671 ◽  
Author(s):  
Daniele Mandolesi ◽  
Marco Lenzi ◽  
Antonietta D’Errico ◽  
Davide Festi ◽  
Franco Bazzoli ◽  
...  
Keyword(s):  
Case Report ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Overlap Syndrome ◽  
Primary Biliary Cholangitis

Primary biliary cholangitis–primary sclerosing cholangitis in an evolving overlap syndrome: A case report

2017 ◽  
Vol 40 (10) ◽  
pp. 669-671
Author(s):  
Daniele Mandolesi ◽  
Marco Lenzi ◽  
Antonietta D’Errico ◽  
Davide Festi ◽  
Franco Bazzoli ◽  
...  
Keyword(s):  
Case Report ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Overlap Syndrome ◽  
Primary Biliary Cholangitis

Cholestatic Liver Injury: Care of Patients With Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

2016 ◽  
Vol 27 (4) ◽  
pp. 441-452 ◽  
Author(s):  
Laurie Larson ◽  
Michelle James ◽  
Andrea Gossard
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Disease Recurrence ◽  
Outpatient Setting ◽  
Primary Biliary Cholangitis ◽  
Malignant Neoplasms ◽  
Cholestatic Liver Disease ◽  
Gallbladder Polyps ◽  
Increased Risk ◽  
Common Causes

The most common causes of chronic cholestatic liver disease are primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). Both disease processes are characterized by a destruction of intrahepatic and/or extrahepatic biliary ducts. The etiology is not entirely clear; however, there is an underlying autoimmune component contributing to both disease processes. Although PBC and PSC are often diagnosed and managed in the outpatient setting, in some instances, a patient may have jaundice, fatigue, and pruritus requiring evaluation and determination of the cholestatic cause. Patients with PSC should be monitored for evidence of cholangiocarcinoma, colon cancer, and gallbladder polyps as they are at an increased risk of malignant neoplasms. Liver transplant has the potential for improving quality of life, although disease recurrence is a risk.

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