scholarly journals Health-related quality of life and associated factors among cervical cancer patients at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Liya Teklu Araya ◽  
Teferi Gedif Fenta ◽  
Beate Sander ◽  
Girma Tekle Gebremariam ◽  
Gebremedhin Beedemariam Gebretekle
2020 ◽  
Author(s):  
Girma Tekle Gebremariam ◽  
Kalikdan Yihenew Bitew ◽  
Yemisrach Tessema Weldeyes ◽  
Atalay Mulu Fentie ◽  
Gebremedhin Beedemariam Gebretekle

Abstract Background: Antiretroviral therapy (ART) has significantly reduced mortality and morbidity of people living with HIV/AIDS (PLWHA); however, the nature of infection and treatment associated with adverse drug reactions often adversely affect patient's health-related quality of life (HRQoL). The purpose of this study was to assess the HRQoL and its associated factors among PLWHA in Ethiopia.Methods: A hospital-based cross-sectional study was conducted among patients taking HAART at Zewditu Memorial General Hospital in Addis Ababa. A face-to-face interview was performed using the HIV/AIDS targeted quality of Life (HAT-QoL) instrument. Patients who met eligibility criteria were approached consecutively while they came to the pharmacy for a medication refill. Descriptive statistics were used to present patient characteristics and HRQoL profiles. Independent t-test and one-way ANOVA were carried out to identify predictors for HRQoL. All statistical tests considered significant at p-value < 0.05.Results: A total of 300 participants were interviewed. The mean age of patients was 41.47 ± 9.45 years and the majority (63.13% ) were females. More than two-thirds (69.7%) of patients were adherents to their medication. The highest HAT-QoL mean score was observed in the overall function domain (84.96±19.87) followed by life satisfaction (83.02±14.61) and physician trust (80.53±20.79). Moderate mean scores were reported in the domains of health worries (71.90±27.00), medication worries (69.44±21.53) and disclosure worries (63.65±30.94) had moderate mean scores, while HIV mastery (56.94±32.52), financial worries (48.81±44.64), and sexual function (12.57±45.56) recorded lower mean scores. Being female, higher educational status, older age, low household income, taking prophylactic therapy, low CD4+ count, and non-adherence were significantly associated with HAT-QoL domains.Conclusions: Overall, HIV/AIDS patients in Addis Ababa had an average level of HRQoL. This study demonstrated that several sociodemographic and clinical variables contribute to reduced HRQoL. Hence, healthcare providers should be paid attention to associated factors that contributed to reduced HRQoL.


2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Helen Lamesgin Endalew ◽  
Bikis Liyew ◽  
Zewdu Baye ◽  
Gebrekidan Ewunetu Tarekegn

Introduction. Myocardial infarction is the most frequent manifestation of coronary heart disease and one of the leading causes of death worldwide. The sudden and often profound physiological and psychological effect of the acute onset of myocardial infarction hurts the health-related quality of life. Objective. To assess health-related quality of life and associated factors among myocardial infarction patients at Cardiac Center, Ethiopia, Addis Ababa, Ethiopia, 2020. Method. Institution-based cross-sectional study was conducted from April 10 to June 25, 2020, at the Cardiac Center-Ethiopia, Addis Ababa, Ethiopia. The sample consisted of 421 myocardial infarction patients. Data were collected through an interviewer-administered structured questionnaire by using the World Health Organization Quality of Life Questionnaire. Samples were selected using a consecutive sampling technique. The linear regression analysis model was fitted using SPSS 26 and STATA 14, and the unstandardized beta (𝛽) coefficient with a 95% confidence interval was used. A p value <0.05 was considered statistically significant for all analyses. Results. The mean score of the overall health-related quality of life was found to be 49.29 ± 14.83 , and the mean score for the physical domain was 47.96 ± 16.50 ; for the psychological domain, it was 50.91 ± 16.07 , and for environmental and social relationship domains, it was 48.30 ± 16.54 and 52.02 ± 24.61 , respectively. In the multiple regression analysis, increased age, living in a rural area, heart failure, and hypertension were inversely associated with overall health-related quality of life, while secondary and higher education were associated with better overall health-related quality of life. Conclusion. Patients with myocardial infarction at Cardiac Center, Ethiopia, had lower health-related quality of life. Hence, the finding of this study suggests the implementation of a cardiac rehabilitation program and comprehensive service given by healthcare providers.


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