scholarly journals Risk factors associated with postoperative complications after liver cancer resection surgery in western China

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Yanjie Hu ◽  
Siyu Zeng ◽  
Lele Li ◽  
Yuanchen Fang ◽  
Xiaozhou He
Keyword(s):  
Factor Analysis ◽  
Logistic Regression ◽  
Postoperative Complications ◽  
Liver Cancer ◽  
Stepwise Logistic Regression ◽  
Single Factor ◽  
Incision Length ◽  
Cancer Resection ◽  
Factors Associated ◽  
Single Factor Analysis

Abstract Objectives Postoperative complications increase the workload of nursing staff as well as the financial and mental distress suffered by patients. The objective of this study is to identify clinical factors associated with postoperative complications after liver cancer resection surgery. Methods Data from liver cancer resections occurring between January 1st, 2019 to December 31st, 2019 was collected from the Department of Liver Surgery in West China Hospital of Sichuan University. The Kruskal–Wallis test and logistic regression were used to perform single-factor analysis. Stepwise logistic regression was used for multivariate analysis. Models were established using R 4.0.2 software. Results Based on data collected from 593 cases, the single-factor analysis determined that there were statistically significant differences in BMI, incision type, incision length, duration, incision range, and bleeding between cases that experienced complications within 30 days after surgery and those did not. Stepwise logistic regression models based on Kruskal–Wallis test and single-factor logistic regression determined that BMI, incision length, and duration were the primary factors causing complications after liver resection. The adjust OR of overweight patients and patients with obesity (stage 1) compared to low weight patients were 0.12 (95% CI:0.02–0.72) with p = 0.043 and 0.18 (95% CI:0.03–1.00) with p = 0.04, respectively. An increase of 1 cm in incision length increased the relative risk by 13%, while an increase of 10 min in surgical duration increased the relative risk by 15%. Conclusions The risk of postoperative complications after liver resection can be significantly reduced by controlling factors such as bleeding, incision length, and duration of the surgery.

scholarly journals Significance of pepsinogen in screening for gastric intestinal metaplasia in Guangdong, China

2021 ◽  
Vol 49 (2) ◽  
pp. 030006052199049
Author(s):  
Xujuan Liu ◽  
Min Zhang ◽  
Riyu Luo ◽  
Keran Mo ◽  
Xingxiang He
Keyword(s):  
Logistic Regression ◽  
Intestinal Metaplasia ◽  
Single Factor ◽  
Antibody Testing ◽  
Cross Sectional ◽  
Gastric Intestinal Metaplasia ◽  
Risk Detection ◽  
Tree Models ◽  
Single Factor Analysis ◽  
Serological Biomarkers

Objective Diagnosis of gastric intestinal metaplasia (GIM) relies on gastroscopy and histopathologic biopsy, but their application in screening for GIM is limited. We aimed to identify serological biomarkers of GIM via screening in Guangdong, China. Methods Cross-sectional field and questionnaire data, demographic information, past medical history, and other relevant data were collected. Blood samples were collected for pepsinogen (PG)I, PGII, gastrin-17, and Helicobacter pylori antibody testing, and gastroscopy and histopathologic biopsy were performed. Single factor and logistic regression analyses were used to evaluate the correlation between these indicators and GIM, and decision tree models were used to determine the cut-off points between indicators. Results Of 443 participants enrolled, 87 (19.6%) were diagnosed with GIM. Single factor analysis showed that pepsin indicators (PGI, PGII, and PGI/PGII ratio) and the factors Mandarin as native language, urban residency, hyperlipidemia, and age were associated with GIM. Logistic regression analysis showed that PGI and age were associated with GIM. Conclusions Age is an important factor for predicting GIM progression; age >60 years increased its risk. Detection of GIM was higher in individuals with PGI levels >127.20 ng/mL, which could be used as a threshold indicating the need to perform gastroscopy and histopathologic biopsy.

scholarly journals Improving Strength and Quality of Epitendinous Repairs

Hand ◽  
2018 ◽  
Vol 15 (4) ◽  
pp. 495-501
Author(s):  
Angel Farinas ◽  
Michael Stephanides ◽  
Steven Schneeberger ◽  
Alonda Pollins ◽  
Nancy Cardwell ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Analysis Of Variance ◽  
Statistical Significance ◽  
Single Factor ◽  
Single Thread ◽  
A2 Pulley ◽  
Suture Thread ◽  
Single Factor Analysis ◽  
Single Suture

Background: Epitendinous sutures not only join the 2 severed tendon edges but also supply strength and support to the repair. Multiple techniques have been described, but none of them include another thread of suture. This could potentially increase the strength of the repair without affecting gliding. Methods: Caprine tendons were harvested, transected, and sutured with 6-0 Prolene. Four groups were created: single thread running (SR), single thread locking (SL), double thread running (DR), and double thread locking (DL). An Instron 5542 was used to pull the repaired tendons apart, and the energy at the break was calculated (gf/mm). For gliding resistance, we harvested a human A2 pulley. A pre- and postrepair value was obtained, and a ratio was elaborated. A single-factor analysis of variance and independent sample t tests were performed. Results: The SR group had a mean energy at break of 9339.71 ± 1630.212 gf/mm; the SL group, 9629.96 ± 1476.45 gf/mm; and the DR group, 9600.221 ± 976.087 gf/mm, with no statistical significance. The DL group was significantly higher at 14 740.664 ± 2596.586 gf/mm ( P < .05). When comparing SR with DL for gliding, SR had less than half of the resistance than DL (0.018 ± 0.004 and 0.049 ± 0.015 N/mm, respectively), with statistical significance ( P < .05). Conclusion: Using a single suture thread for running epitendinous repair is no different than locking with a single thread or using an extra thread in a running fashion. Performing a double suture thread with a locking technique is significantly stronger than the previously mentioned repairs, with the disadvantage of more resistance at the pulley.

scholarly journals Multi-Dimensional Factors Associated with Illegal Substance Use Among Gay and Bisexual Men in Taiwan

2019 ◽  
Vol 16 (22) ◽  
pp. 4476 ◽  
Author(s):  
Dian-Jeng Li ◽  
Shiou-Lan Chen ◽  
Cheng-Fang Yen
Keyword(s):  
Substance Use ◽  
Logistic Regression ◽  
Early Adulthood ◽  
Gay And Bisexual Men ◽  
Stepwise Logistic Regression ◽  
Childhood And Adolescence ◽  
Bisexual Men ◽  
Cross Sectional ◽  
Factors Associated ◽  
And Bisexual

Illegal substance use in sexual minorities is an important health issue worldwide. The present cross-sectional study aimed to investigate the multi-dimensional factors associated with illegal substance use among gay and bisexual men in Taiwan. This questionnaire-survey study recruited 500 gay or bisexual men aged between 20 and 25 years. Their experiences of using eight kinds of illegal substances in the preceding month were collected. Their previous experiences of homophobic bullying, satisfaction with academic performance, truancy, perceived family and peer support in childhood and adolescence, and social-demographic characteristics, were also collected. Potential factors associated with illegal substance use were identified using univariate logistic regression, and further selected into a forward stepwise logistic regression model to identify the factors most significantly related to illegal substance use. A total of 22 (4.4%) participants reported illegal substance use in the preceding month, and mean age was 22.9 ± 1.6. Forward stepwise logistic regression revealed that being victims of homophobic cyberbullying in childhood and adolescence (odds ratio (OR) = 1.26; p = 0.011), disclosure of sexual orientation at junior high school (OR = 4.67; p = 0.001), and missing classes or truancy in senior high school (OR = 2.52; p = 0.041) were significantly associated with illegal substance use in early adulthood. Multi-dimensional factors in childhood and adolescence that were significantly associated with illegal substance use in early adulthood among gay and bisexual men were identified. Besides traditional bullying, the effect of cyberbullying and school performance on illegal substance use should not be ignored. This study is limited to the cross-sectional design and possible recall bias. Mental health professionals must routinely assess these significant factors to prevent and intervene in illegal substance use among gay and bisexual men.

scholarly journals Investigation of Influence ofa New Twist Intensifier on the Properties of the Twisted Yarn

2021 ◽  
Vol 12 (5) ◽  
pp. 1943-1949
Author(s):  
Yuldashev Alisher Tursunbayevich, Et. al.
Keyword(s):  
Tensile Strength ◽  
Factor Analysis ◽  
Uniform Distribution ◽  
Statistical Methods ◽  
Quality Parameters ◽  
Single Factor ◽  
Rotor Spinning ◽  
Twisted Yarn ◽  
Single Factor Analysis

The article is devoted to the study of the properties of the yarn obtained by the methods of ring and rotor spinning, for twisted yarn, produced on a VTS-09 double twist machine made by Volkmann (Germany). Experiments were carried out on two typesof spinning yarns with yarn counts Ne 20/2 and 12/2 in the existing design (control) and the new design, flexible element with equal tension and twist intensifier and compared the effects of the resulting twisted yarn for quality parameters. Mathematical statistical methods (single-factor analysis of variance) were used to assess the quality of twisted yarn. Experiments have shown that the use of a new design nozzle reduces the vibration of the yarn, which leads to a uniform distribution of twists along the length of the twisted yarn, increases its tensile strength and improves the quality of the twisted yarn.

scholarly journals Coagulopathy and damage control resuscitation during transfer due to massive hemorrhage –a single-center retrospective study–

2020 ◽  
Author(s):  
Hiroyuki Takahashi ◽  
Tomohisa Shoko ◽  
Mitsuaki Kojima ◽  
Satoshi Nara
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Damage Control ◽  
Massive Hemorrhage ◽  
Categorical Variables ◽  
Stepwise Logistic Regression ◽  
Damage Control Resuscitation ◽  
Single Center ◽  
Factors Associated

Abstract Background: To assess medical procedures, particularly damage control resuscitation, at the time of transfer between hospitals for the purpose of treating massive hemorrhage.Methods: This study used a single-center retrospective observational design, enrolling patients referred to Teine Keijinkai Hospital from another hospital between April 2012 and March 2019 for the treatment of massive hemorrhage. We excluded patients who entered cardiac arrest before arriving at our center. Qualitative or categorical variables were compared using the χ2 or Fisher’s exact test, as appropriate. Quantitative continuous variables were compared using Mann-Whitney nonparametric tests, as appropriate. Risk factors associated with coagulopathy from univariate analyses (fibrinogen level £150 mg/dl; prothrombin time-international normalized ratio ³1.5) were entered into stepwise logistic regression analysis. Significance was defined for values of p < 0.05.Results: Multiple logistic regression analysis revealed trauma (odds ratio (OR) 4.800; 95% confidence interval (CI) 2.016–11.433; p < 0.001) and volume of crystalloid solution (OR 1.001; 95%CI 1.000–1.001; p = 0.008) as independent factors associated with coagulopathy. Patients with coagulopathy showed higher 24-h mortality rates (10.9%) than patients without coagulopathy (1.2%; p = 0.021), and cause of death was hemorrhagic shock for all cases of death within 24 h.Conclusion: In our area, withholding intravenous fluid to achieve permissive hypotension, early administration of fresh frozen plasma, and use of fibrinogen concentrate may improve the prognosis of patients with massive hemorrhage undergoing transfer between hospitals.Trial registration: UMIN, UMIN000041201. Registered 24 July 2020 – Retrospectively registered, https://upload.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000047048

scholarly journals Spatiotemporal variations of asthma admission rates and its relationship with environmental factors in Guangxi, China

2019 ◽  
Author(s):  
Rui Ma ◽  
Lizhong Liang ◽  
Yunfeng Kong ◽  
Mingyang Chen ◽  
Shiyan Zhai ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Environmental Factors ◽  
Hospital Admissions ◽  
Meteorological Factors ◽  
Synergistic Effects ◽  
Single Factor ◽  
Hospitalization Rates ◽  
Multiple Regions ◽  
Asthma Hospitalization ◽  
Single Factor Analysis

Abstract BackgroundThe association between environmental factors and asthma has attracted much attention. Numerous studies have focused on the effects of air pollution or meteorological factors, but the synergistic effects and regional heterogeneity remain unclear. MethodsBetween 2014 and 2015, 8,563 hospital admissions in 2014 and 7,804 hospital admissions in 2015 due to asthma were collected from 14 regions in Guangxi, China. First, we performed a Spearman correlation coefficient model as the single factor analysis to estimate correlation between environmental factors and asthma hospitalization rates in multiple regions. Second, Generalized Additive Model (GAM) was used to analyze the synergistic effects of environmental factors on asthma hospitalization rates in 14 regions, respectively.ResultsThe results indicated that asthma hospitalization rates were high in spring and autumn. There were all nonlinear relationships between air pollutants, meteorological factors and asthma hospitalization rates, and the relationships were different from region to region. According to the single factor analysis, asthma hospitalizations were related to the daily temperature, daily range of temperature, CO, NO2, and PM2.5 in multiple regions. According to the result of synergistic effects analysis, the adjusted R-square was high in Beihai and Nanning, with values of 0.292 and 0.207, which meant that environmental factors were powerful in explaining changes of asthma hospitalization rates in Beihai and Nanning.ConclusionDaily range of temperature is an important factor impact on asthma, which should be considered in the analysis of environmental factors impact on asthma. It is suggested that the relationship between asthma and risk factors in different regions deserves additional study. Governments should develop targeted protective measures for asthma in different regions.

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