scholarly journals Autologous full-thickness skin graft as reinforcement in parastomal hernia repair: a randomised controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Viktor Holmdahl ◽  
Ulf Gunnarsson ◽  
Karin Strigård
Keyword(s):  
Hernia Repair ◽  
Skin Graft ◽  
Parastomal Hernia ◽  
Controlled Trial ◽  
Full Thickness ◽  
Full Thickness Skin Graft ◽  
Full Thickness Skin ◽  
Thickness Skin ◽  
Parastomal Hernia Repair ◽  
Randomised Controlled

Abstract Background Parastomal hernia is a common complication of an enterostomy and can have a significant impact on health-related quality of life. Currently used methods of repair have high recurrence rates and considerable risk for complications. We have developed a new technique for parastomal hernia repair that uses full-thickness skin graft as reinforcement. Methods This study protocol describes a multicentre randomised controlled trial on parastomal hernia repair comparing a new full-thickness skin graft technique with conventional synthetic composite mesh as reinforcement of the abdominal wall. Patients with a symptomatic parastomal hernia will be included and followed up at 3, 12 and 36 months, with surgical complication as the primary outcome. Secondary outcomes will be recurrence rate and health-related quality of life assessed with VHPQ, EORTC C30 and CR29. Tissue biology and collagen metabolism will be investigated pre- and postoperatively using biopsies of the abdominal wall fascia and blood samples. Discussion Parastomal hernia constitutes a major clinical problem where the prospects of a good result after hernia repair are presently poor. This new method of repair with full-thickness skin grafting could be a new alternative in our surgical toolbox, but before then, it must be evaluated properly. Trial registration ClinicalTrials.gov NCT03667287. Registered on September 12, 2018

scholarly journals Autologous full-thickness skin graft as reinforcement in parastomal hernia repair: a feasibility study

2020 ◽  
Author(s):  
V. Holmdahl ◽  
U. Gunnarsson ◽  
K. Strigård
Keyword(s):  
Hernia Repair ◽  
Skin Graft ◽  
Parastomal Hernia ◽  
Complication Rates ◽  
Full Thickness ◽  
Full Thickness Skin Graft ◽  
Full Thickness Skin ◽  
Thickness Skin ◽  
Parastomal Hernia Repair

Abstract Background Parastomal hernia is a common complication of stoma formation and the methods of repair available today are unsatisfactory with high recurrence and complication rates. To improve outcome after surgical repair of parastomal hernia, a surgical method using autologous full-thickness skin grafts as intraperitoneal reinforcement has been developed. The purpose of this study was to evaluate the feasibility of this novel surgical technique in the repair of parastomal hernia. Methods A pilot study was conducted between January 2018 and June 2019 on four patients with symptomatic parastomal hernia. They had a laparotomy with suture reduction of the hernia and reinforcement of the abdominal wall with autologous full-thickness skin. They were then monitored for at least 1 year postoperatively for technique-related complications and recurrence. Results No major technique-related complications were noted during the follow-up Two patients developed a recurrent parastomal hernia at the long term follow-up. The other two had no recurrence. Conclusions Autologous full-thickness skin graft as reinforcement in parastomal hernia repair is feasible and should be evaluated in a larger clinical trial.

Early wound repair versus later scar repair in children with treadmill hand friction burns

2021 ◽  
Author(s):  
Rong Zhou ◽  
Lin Qiu ◽  
Jun Xiao ◽  
Xiaobo Mao ◽  
Xingang Yuan
Keyword(s):  
Skin Graft ◽  
Wound Repair ◽  
Full Thickness ◽  
Full Thickness Skin Graft ◽  
Vacuum Sealing ◽  
Full Thickness Skin ◽  
Thickness Skin ◽  
Vacuum Sealing Drainage ◽  
Repair Group ◽  
Hand Friction

Abstract The incidence of pediatric treadmill hand friction burns has been increasing every year. The injuries are deeper than thermal hand burns, the optimal treatment remains unclear. This was a retrospective study of children who received surgery for treadmill hand friction burns from January 1, 2015, to December 31, 2019, in a single burn center. A total of 22 children were surveyed. The patients were naturally divided into two groups: the wound repair group (13 patients), which was admitted early to the hospital after injury and received debridement and vacuum sealing drainage initially, and a full-thickness skin graft later; and the scar repair group (9 patients), in which a scar contracture developed as a result of wound healing and received scar release and skin grafting later. The Modified Michigan Hand Questionnaire score in the wound repair group was 116.31 ± 10.55, and the corresponding score in the scar repair group was 117.56 ± 8.85 (P>0.05), no statistically significant difference. The Vancouver Scar Scale score in the wound repair group was 4.15 ± 1.21, and the corresponding score in the scar repair group was 7.22 ± 1.09 (P<0.05). Parents were satisfied with the postoperative appearance and function of the hand. None in the two groups required secondary surgery. If the burns are deep second degree, third degree, or infected, early debridement, vacuum sealing drainage initially, and a full-thickness skin graft can obviously relieve pediatric pain, shorten the course of the disease, and restore the function of the hand as soon as possible.

Full thickness skin graft urethroplasty for anterior urethral strictures

Urology ◽  
1979 ◽  
Vol 13 (1) ◽  
pp. 45-48 ◽  
Author(s):  
G. Coleman Oswalt ◽  
L. Keith Lloyd ◽  
A.J. Bueschen
Keyword(s):  
Skin Graft ◽  
Full Thickness ◽  
Full Thickness Skin Graft ◽  
Full Thickness Skin ◽  
Urethral Strictures ◽  
Thickness Skin
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