scholarly journals Shared genetic influences between dimensional ASD and ADHD symptoms during child and adolescent development

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Evie Stergiakouli ◽  
George Davey Smith ◽  
Joanna Martin ◽  
David H. Skuse ◽  
Wolfgang Viechtbauer ◽  
...  
Keyword(s):  
Adolescent Development ◽  
Child And Adolescent ◽  
Genetic Influences ◽  
Adhd Symptoms ◽  
Shared Genetic

scholarly journals Evidence for Shared Genetic Influences on Self-Reported ADHD and Autistic Symptoms in Young Adult Australian Twins

2008 ◽  
Vol 11 (6) ◽  
pp. 579-585 ◽  
Author(s):  
Angela M. Reiersen ◽  
John N. Constantino ◽  
Marisa Grimmer ◽  
Nicholas. G. Martin ◽  
Richard D. Todd
Keyword(s):  
Young Adult ◽  
Structural Equation ◽  
Self Report ◽  
Genetic Influences ◽  
Equation Modeling ◽  
Phenotypic Correlation ◽  
Social Responsiveness ◽  
Adhd Symptoms ◽  
Autistic Symptoms ◽  
Shared Genetic

AbstractRecent clinic-based and population-based studies have shown evidence of association between ADHD and autistic symptoms in children and adolescents as well as evidence for genetic overlap between these disorders. The objective of the current study was to confirm the association between autistic and ADHD symptoms in a young adult twin sample assessed by self-report, and investigate whether shared genetic and/or environmental factors can explain the association. We performed twin-based structural equation modeling using self-report data from 11 Social Responsiveness Scale (SRS) items and 12 DSM-IV ADHD inattentive and impulsive symptom items obtained from 674 young adult Australian twins. Phenotypic correlation between autistic and ADHD symptoms was moderate. The most parsimonious univariate models for SRS and ADHD included additive genetic effects and unique environmental effects, without sex differences. ADHD and autistic traits were both moderately heritable. In a bivariate model, genetic correlation (rg) between SRS and ADHD was 0.72. Our results suggest that in young adults, a substantial proportion of the genetic influences on self-reported autistic and ADHD symptoms may be shared between the two disorders.

scholarly journals Shared genetic influences on ADHD symptoms and very low-frequency EEG activity: a twin study

2011 ◽  
Vol 53 (6) ◽  
pp. 706-715 ◽  
Author(s):  
Charlotte Tye ◽  
Frühling Rijsdijk ◽  
Corina U. Greven ◽  
Jonna Kuntsi ◽  
Philip Asherson ◽  
...  
Keyword(s):  
Twin Study ◽  
Low Frequency ◽  
Genetic Influences ◽  
Adhd Symptoms ◽  
Eeg Activity ◽  
Very Low Frequency ◽  
Shared Genetic

Review of Child and Adolescent Development (2nd ed.).

1987 ◽  
Vol 32 (2) ◽  
pp. 191-192
Author(s):  
W. Andrew Collins
Keyword(s):  
Adolescent Development ◽  
Child And Adolescent

scholarly journals DSM-IV defined conduct disorder and oppositional defiant disorder: an investigation of shared liability in female twins

2013 ◽  
Vol 44 (5) ◽  
pp. 1053-1064 ◽  
Author(s):  
V. S. Knopik ◽  
L. C. Bidwell ◽  
C. Flessner ◽  
N. Nugent ◽  
L. Swenson ◽  
...  
Keyword(s):  
Conduct Disorder ◽  
Oppositional Defiant Disorder ◽  
Hierarchical Structure ◽  
Environmental Effects ◽  
Genetic Influences ◽  
Two Stage ◽  
Genetic Studies ◽  
Oppositional Defiant ◽  
Dsm Iv ◽  
Shared Genetic

BackgroundDSM-IV specifies a hierarchal diagnostic structure such that an oppositional defiant disorder (ODD) diagnosis is applied only if criteria are not met for conduct disorder (CD). Genetic studies of ODD and CD support a combination of shared genetic and environmental influences but largely ignore the imposed diagnostic structure.MethodWe examined whether ODD and CD share an underlying etiology while accounting for DSM-IV diagnostic specifications. Data from 1446 female twin pairs, aged 11–19 years, were fitted to two-stage models adhering to the DSM-IV diagnostic hierarchy.ResultsThe models suggested that DSM-IV ODD–CD covariation is attributed largely to shared genetic influences.ConclusionsThis is the first study, to our knowledge, to examine genetic and environmental overlap among these disorders while maintaining a DSM-IV hierarchical structure. The findings reflect primarily shared genetic influences and specific (i.e. uncorrelated) shared/familial environmental effects on these DSM-IV-defined behaviors. These results have implications for how best to define CD and ODD for future genetically informed analyses.

The Field of Child and Adolescent Development

2018 ◽  
pp. 3-10
Author(s):  
Kimberly A. Gordon Biddle ◽  
Aletha M. Harven ◽  
Cynthia Hudley
Keyword(s):  
Adolescent Development ◽  
Child And Adolescent
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