scholarly journals Evidence for Shared Genetic Influences on Self-Reported ADHD and Autistic Symptoms in Young Adult Australian Twins

2008 ◽  
Vol 11 (6) ◽  
pp. 579-585 ◽  
Author(s):  
Angela M. Reiersen ◽  
John N. Constantino ◽  
Marisa Grimmer ◽  
Nicholas. G. Martin ◽  
Richard D. Todd

AbstractRecent clinic-based and population-based studies have shown evidence of association between ADHD and autistic symptoms in children and adolescents as well as evidence for genetic overlap between these disorders. The objective of the current study was to confirm the association between autistic and ADHD symptoms in a young adult twin sample assessed by self-report, and investigate whether shared genetic and/or environmental factors can explain the association. We performed twin-based structural equation modeling using self-report data from 11 Social Responsiveness Scale (SRS) items and 12 DSM-IV ADHD inattentive and impulsive symptom items obtained from 674 young adult Australian twins. Phenotypic correlation between autistic and ADHD symptoms was moderate. The most parsimonious univariate models for SRS and ADHD included additive genetic effects and unique environmental effects, without sex differences. ADHD and autistic traits were both moderately heritable. In a bivariate model, genetic correlation (rg) between SRS and ADHD was 0.72. Our results suggest that in young adults, a substantial proportion of the genetic influences on self-reported autistic and ADHD symptoms may be shared between the two disorders.

2013 ◽  
Vol 43 (9) ◽  
pp. 1973-1984 ◽  
Author(s):  
A. Merwood ◽  
C. U. Greven ◽  
T. S. Price ◽  
F. Rijsdijk ◽  
J. Kuntsi ◽  
...  

BackgroundParent and teacher ratings of attention deficit hyperactivity disorder (ADHD) symptoms yield high estimates of heritability whereas self-ratings typically yield lower estimates. To understand why, the present study examined the etiological overlap between parent, teacher and self-ratings of ADHD symptoms in a population-based sample of 11–12-year-old twins.MethodParticipants were from the Twins Early Development Study (TEDS). ADHD symptoms were assessed using the Strengths and Difficulties Questionnaire (SDQ) hyperactivity scale completed by parents, teachers and children. Structural equation modeling was used to examine genetic and environmental contributions to phenotypic variance/covariance.ResultsThe broad-sense heritability of ADHD symptoms was 82% for parent ratings, 60% for teacher ratings and 48% for self-ratings. Post-hoc analyses revealed significantly higher heritability for same-teacher than different-teacher ratings of ADHD (76% v. 49%). A common pathway model best explained the relationship between different informant ratings, with common genetic influences accounting for 84% of the covariance between parent, teacher and self-rated ADHD symptoms. The remaining variance was explained by rater-specific genetic and non-shared environmental influences.ConclusionsDespite different heritabilities, there were shared genetic influences for parent, teacher and self-ratings of ADHD symptoms, indicating that different informants rated some of the same aspects of behavior. The low heritability estimated for self-ratings and different-teacher ratings may reflect increased measurement error when different informants rate each twin from a pair, and/or greater non-shared environmental influences. Future studies into the genetic influences on ADHD should incorporate informant data in addition to self-ratings to capture a pervasive, heritable component of ADHD symptomatology.


Assessment ◽  
2020 ◽  
pp. 107319112090589
Author(s):  
Rapson Gomez ◽  
Vasileios Stavropoulos

This study examined the structure of attention-deficit/hyperactivity disorder (ADHD) symptoms in an adult community sample using first-order confirmatory factor analysis, exploratory structural equation modeling (ESEM), and bifactor confirmatory factor analysis and ESEM models, with two group factors (inattention [IA] and hyperactivity/impulsivity [HY/IM]) and two different three group factors (IA, hyperactivity [HY], and impulsivity [IM]; and IA, motoric HY/IM, and verbal HY/IM). A total of 738 adults (males = 374 and females = 364) between 17 and 72 years of age completed the Adult ADHD Self-Report Scale. The results provided most support for the ESEM model with group factors for IA, motoric HY/IM, and verbal HY/IM. The factors in this model were reasonably well defined, had good internal consistency omega reliabilities, and had support for their external validities, thereby making it a suitable model for ratings of the ADHD symptoms presented in the Adult ADHD Self-Report Scale. The theoretical and clinical implications of the findings are discussed.


2021 ◽  
pp. 026540752098115
Author(s):  
Isabel Miguel ◽  
Alexandra M. Araújo ◽  
Sandra Fernandes ◽  
Luísa Carneiro ◽  
Paula Fernandes

Given the crucial role that grandparents play in the upbringing and well-being of their grandchildren, research regarding the perceived importance of grandparents for their emerging adult grandchildren is of particular relevance. This study examined the relations between perceived grandparents’ roles and family and life satisfaction in Portuguese emerging adults. Participants (N = 387), aged 18–25, completed a structured self-report questionnaire. Findings of structural equation modeling showed that emerging adults’ perceptions of grandparental roles of counselor, enjoying the relationship, and indulgence are positively related to their family and life satisfaction. The mediation analysis showed that family satisfaction mediated the relation between perceptions of grandparents acting as counselors and the life satisfaction of emerging adult grandchildren. Implications of family relationships and grandparenting in the context of emerging adulthood are discussed.


2021 ◽  
Vol 229 (1) ◽  
pp. 24-37 ◽  
Author(s):  
Nadine Wedderhoff ◽  
Timo Gnambs ◽  
Oliver Wedderhoff ◽  
Tanja Burgard ◽  
Michael Bošnjak

Abstract. The Positive and Negative Affect Schedule (PANAS; Watson et al., 1988 ) is a popular self-report questionnaire that is administered all over the world. Though originally developed to measure two independent factors, different models have been proposed in the literature. Comparisons among alternative models as well as analyses concerning their robustness in cross-national research have left an inconclusive picture. Therefore, the present study evaluates the dimensionality of the PANAS and differences between English and translated versions of the PANAS using a meta-analytic structural equation modeling approach. Correlation matrices from 57 independent samples ( N = 54,043) were pooled across subsamples. For both English and non-English samples, a correlated two-factor model including correlated uniquenesses provided the best fit. However, measurement invariance analyses indicated differences in factor loadings between subsamples. Thus, cross-national application of the PANAS might only be justified if measurement equivalence was explicitly tested for the countries at hand.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Lei Xie ◽  
Soo Jeoung Han ◽  
Michael Beyerlein ◽  
Jiacheng Lu ◽  
Lillian Vukin ◽  
...  

Purpose This paper aims to conduct two studies to investigate shared leadership and team creativity (TC) in leaderless short-term project teams (STPTs). Design/methodology/approach To answer the research question, this paper used a multi-level mixed-methods design. This paper analyzed video recordings, transcripts of STPTs’ collaboration and self-report surveys from an international engineering competition. In Study 1, this paper attempted to connect relation-oriented shared leadership (ROSL) and task-oriented shared leadership (TOSL) with TC by coding video recordings. In Study 2, this paper further investigated the proposed positive relationship between shared leadership and TC by surveying a sample of 166 students in 51 teams. Findings In Study 1, this paper found that shared leadership covaries with TC following a similar behavioral pattern. In Study 2, multi-level structural equation modeling results suggested that both TOSL and ROSL are positively correlated with TC. Originality/value In this mixed-methods multi-level research, this paper found that when the team’s shared leadership increases, their TC activity becomes frequent. This paper confirmed the qualitative finding by quantitatively investigated the relationship between shared leadership and creativity at the team level.


2020 ◽  
Vol 27 (4) ◽  
pp. 154-170 ◽  
Author(s):  
L. Nusser ◽  
O. Pollatos ◽  
D. Zimprich

Abstract. Background: The current research into interoception distinguishes between interoceptive accuracy (IAcc), the accurate detection of internal sensations (e.g., heartbeats) as measured by performance on objective IAcc tasks, and interoceptive sensibility (IS), the subjective belief concerning one’s own experience of internal sensations as measured either through self-report questionnaires or through one’s confidence in the accuracy during an IAcc task. Aims: As the two measures of IS, however, are usually uncorrelated and show differential relationships to IAcc, we suggest different types of IS, a general IS and a specific IS. Further, based on a growing body of research linking IAcc and IS to physical and mental diseases, the development of interoception across the adult lifespan is of importance. Methods: Using Structural Equation Modeling the present paper investigates the relationships among IAcc assessed by a heartbeat counting task, and the two proposed dimensions of IS in 138 participants ( Mage = 42.67, SDage = 18.77). Furthermore, we examine age-related differences in IAcc, as well as in general and specific IS. Results: In terms of the relationship between the three dimensions, general and specific IS were weakly correlated and exhibited different relationships to IAcc. Further, we found different age effects on the three interoceptive dimensions. Whereas IAcc decreased with age, specific IS tend to increase with age, and general IS remained unaffected by age. Conclusion: The findings provide further empirical support for a dissociation between general and specific IS and raised important questions concerning the relation between interoceptive accuracy and the emergence of physical diseases in older age.


2018 ◽  
Vol 40 (6) ◽  
pp. 946-963 ◽  
Author(s):  
Sean Robert Valentine ◽  
David Hollingworth ◽  
Patrick Schultz

Purpose Focusing on ethical issues when making organizational decisions should encourage a variety of positive outcomes for companies and their employees. The purpose of this paper is to determine the degree to which data-based ethical decision making, lateral relations and organizational commitment are interrelated in organizations. Design/methodology/approach Data were collected from business professionals employed at multiple locations of a financial services firm operating in the USA. Mediation analysis (based on structural equation modeling) was used to test the proposed relationships. Findings Results indicated that employees’ perceptions of data-based ethical decision making were positively related to perceived lateral relations, and that perceived lateral relations were positively related to organizational commitment. Research limitations/implications Given that information was collected using only a self-report questionnaire, common method bias could be an issue. In addition, the study’s cross-sectional design limits conclusions about causality. Another limitation involves the study’s homogenous sample, which decreases the generalizability of the findings. Finally, variable responses could have been impacted by individual frames of reference and other perceptual differences. Practical implications Results suggest that information flow enhancements should support or be consistent with horizontal information flow enhancements, and that together these factors should increase employee commitment. Originality/value Given the dearth of existing research, this interdisciplinary investigation is important because it fills gaps in the management literature. This study is also important because the results could inform decisions regarding the use of data analysis in ethical decisions and lateral forms of organizational structuring to improve work attitudes.


Medicina ◽  
2007 ◽  
Vol 43 (5) ◽  
pp. 425 ◽  
Author(s):  
Saule Raižiene ◽  
Aukse Endriulaitiene

The objective of this study was to determine whether empathy and occupational commitment significantly contribute to the emotional exhaustion of nurses. The sample group was 158 nurses from two regional Lithuanian hospitals, who completed self-report measures. A questionnaire consisted of 10 items reflecting empathy appearing on Davis (1983) Indi- vidual Reactivity Index, 4 occupational commitment items from Miller et al. (1988), and 7 emotional exhaustion items from the Maslach Burnout Inventory (Maslach, Jackson, 1981). Correlation analyses and structural equation modeling were employed to interpret the results. The results showed that nurses’ occupational commitment plays an important role in the degree of emotional exhaustion they experience. Nurses having more empathy are more likely to develop higher occupational commitment. In addition, it was found that higher levels of empathy and occupational commitment of nurses are associated with lower emotional exhaustion. Nurses who stayed in the profession longer developed stronger occupational commitment. Therefore, the conclusion was made that differences in emotional exhaustion among nurses may be explained directly by occupational commitment and indirectly by empathy and nursing experience.


CNS Spectrums ◽  
2018 ◽  
Vol 24 (04) ◽  
pp. 426-440 ◽  
Author(s):  
Jeggan Tiego ◽  
Sanne Oostermeijer ◽  
Luisa Prochazkova ◽  
Linden Parkes ◽  
Andrew Dawson ◽  
...  

ObjectiveImpulsivity and compulsivity have been implicated as important transdiagnostic dimensional phenotypes with potential relevance to addiction. We aimed to develop a model that conceptualizes these constructs as overlapping dimensional phenotypes and test whether different components of this model explain the co-occurrence of addictive and related behaviors.MethodsA large sample of adults (N = 487) was recruited through Amazon’s Mechanical Turk and completed self-report questionnaires measuring impulsivity, intolerance of uncertainty, obsessive beliefs, and the severity of 6 addictive and related behaviors. Hierarchical clustering was used to organize addictive behaviors into homogenous groups reflecting their co-occurrence. Structural equation modeling was used to evaluate fit of the hypothesized bifactor model of impulsivity and compulsivity and determine the proportion of variance explained in the co-occurrence of addictive and related behaviors by each component of the model.ResultsAddictive and related behaviors clustered into 2 distinct groups: Impulse-Control Problems, consisting of harmful alcohol use, pathological gambling, and compulsive buying, and Obsessive-Compulsive-Related Problems, consisting of obsessive-compulsive symptoms, binge eating, and internet addiction. The hypothesized bifactor model of impulsivity and compulsivity provided the best empirical fit, with 3 uncorrelated factors corresponding to a general Disinhibition dimension, and specific Impulsivity and Compulsivity dimensions. These dimensional phenotypes uniquely and additively explained 39.9% and 68.7% of the total variance in Impulse-Control Problems and Obsessive-Compulsive-Related Problems.ConclusionA model of impulsivity and compulsivity that represents these constructs as overlapping dimensional phenotypes has important implications for understanding addictive and related behaviors in terms of shared etiology, comorbidity, and potential transdiagnostic treatments.


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