scholarly journals Network meta-analysis of short-term effects of different strategies in the conservative treatment of AIS

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Kepeng Li ◽  
Jun Miao ◽  
Jingan Zhang

Abstract Purpose To evaluate the short-term effects of different conservative treatments on in adolescent idiopathic scoliosis. Methods By searching the relevant literature of adolescent idiopathic scoliosis, the curative effects of the three regimens of bracing therapy combined with scoliosis-specific exercises, simple treatment with brace and simple scoliosis-specific exercises were compared. Review manager 5.3, Stata MP16 and Network software packages were used for Reticular Meta-analysis of Cobb’s angles before and after treatment. Results A total of 364 patients were included in four clinical studies. Reticular meta-analysis showed that the short-term effect of bracing treatment combined with scoliosis-specific exercises was better than that of treatment with brace and scoliosis-specific exercises, with effects of 2.71(95% CI 0.83–4.58) and 3.67(95% CI 1.21–6.14), respectively. There was no statistical difference between simple bracing therapy and scoliosis-specific exercises. Conclusion Among the three common conservative treatments of adolescent idiopathic scoliosis, the short-term effect of bracing treatment combined with scoliosis-specific exercises is better than that of bracing treatment or scoliosis-specific exercises.

2013 ◽  
Vol 22 (11) ◽  
pp. 2399-2406 ◽  
Author(s):  
Philippe Mahaudens ◽  
Xavier Banse ◽  
Maryline Mousny ◽  
Maxime Raison ◽  
Christine Detrembleur

Author(s):  
Esther Veldhoen ◽  
Anneloes De Vries ◽  
Joyce Tersmette ◽  
Laura Verweij-Van Den Oudenrijn ◽  
Erik Hulzebos ◽  
...  

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Eva Hydbring-Sandberg ◽  
Elin Larsson ◽  
Andrzej Madej ◽  
Odd Viking Höglund

Abstract Objective This study aimed to investigate the short-term effect of ovariohysterectomy on urine levels of serotonin and its relation to levels of cortisol, testosterone and progesterone in female dogs. Seven bitches were studied before surgical ovariohysterectomy and then once a week during 4 weeks. Spontaneously voided urine samples were collected and concentration ratios of hormone/creatinine in urine were analysed. Results The bitches had significantly lower levels of cortisol, testosterone, and progesterone 1 week after ovariohysterectomy compared with before and the levels stayed low throughout the study (P ≤ 0.05). Interestingly, serotonin levels tended to increase 4 weeks after surgery (P = 0.08). A positive correlation between cortisol and progesterone was found before and after surgery. After surgery, serotonin was positively correlated with cortisol and progesterone (P ≤ 0.05).


2020 ◽  
Author(s):  
Hui Lian ◽  
Xin Ding ◽  
Hongmin Zhang ◽  
Xiaoting Wang

Abstract INTRODUCTION: Cardiovascular diseases (CVD) and stroke are leading causes of death. It has several risk factors including stress and pressure. Stock volatility can cause acute stress for stock holders, so it can cause CVD events. Recently the spread of new coronaviruses worldwide has greatly affected economic development, leading to more severe stock market fluctuation, so we systematically quantify the short-term effect of stock volatility and CVD events.METHODS AND MATERIALS: Time-series analysis on effect of stock volatility and cardiovascular events were included. We conducted systematic review and meta-analysis. 4 studies were included in the final analysis.RESULTS: Every 100-point increase in the stock market will bring about 1.01% increases in the cardiovascular mortality (95% CI, -0.18% to 2.21%) The meta-analysis showed no statistical significance for cardiovascular mortality. In terms of stroke event, the estimate effect was 2.999% (95%CI, 0.325% to 5.673%). Different lag patterns also had effects on cardiovascular mortality. Every 100-point increase brought about 4.026% (95%CI, 1.516% to 6.536%) and 4.424% (95%CI, 1.145% to 7.703%) for lag 01 and 04 separately. Conclusions: Our study suggested that stock volatility had lag effect on CVD mortality. It may last for several days. Also, it might increase the incidence of stroke.


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