scholarly journals Successful management of dexmedetomidine for postoperative intensive care sedation in a patient with anti-NMDA receptor encephalitis: a case report and animal experiment

SpringerPlus ◽  
2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Daiki Yamanaka ◽  
Takashi Kawano ◽  
Hiroki Tateiwa ◽  
Hideki Iwata ◽  
Fabricio M. Locatelli ◽  
...  
2013 ◽  
Vol 2013 ◽  
pp. 1-2 ◽  
Author(s):  
Michael MacMahon ◽  
Morag R. Naysmith ◽  
Stephanie McCallion ◽  
Jonathan Rhodes

A young lady was ventilated on intensive care for a prolonged period with NMDA receptor encephalitis. She had undergone steroid, immunoglobulin, and plasmapheresis with no evidence of recovery. Her main management issue was the control of severe orofacial and limb dyskinesia. Large doses of sedating agents had been used to control the dystonia but were ineffective, unless she was fully anaesthetised. The introduction of a ketamine infusion was associated with a dramatic improvement in her symptoms such that it was possible to remove her tracheostomy two days after commencement. She was discharged shortly after that and is making a good recovery. The successful use of ketamine has not previously been described in this context, and we hope this case report will provide some insight into the management of this rare but serious condition.


2020 ◽  
Vol 11 (1) ◽  
pp. 45-48
Author(s):  
Natalie Neale ◽  
Cody Nathan ◽  
Sok Lee ◽  
Atul Kalanuria

We present a case of a 47-year-old female who presented with altered mental status and was found to have severe anti-NMDA receptor encephalitis. Her intensive care unit course was complicated by paroxysmal sympathetic storming. She also had urinary retention for which a catheter was placed early in her admission, but attempts at removal were associated with worsening storming. Her average Clinical Features Scale score was 5.9 when the catheter was not in place compared to 3.6 with the catheter in place. This is the first case report to our knowledge demonstrating an association between urinary catheter removal and autonomic storming in anti-NMDA receptor encephalitis.


2020 ◽  
Vol 87 ◽  
pp. 179-181 ◽  
Author(s):  
Adelaide Panariello ◽  
Roberta Bassetti ◽  
Anna Radice ◽  
Roberto Rossotti ◽  
Massimo Puoti ◽  
...  

2011 ◽  
Vol 26 (7) ◽  
pp. 811-816 ◽  
Author(s):  
Gregory S. Day ◽  
Sasha M. High ◽  
Bianca Cot ◽  
David F. Tang-Wai

2016 ◽  
Vol 5 (6) ◽  
pp. 845-849 ◽  
Author(s):  
Elzbieta Rypulak ◽  
Michal Borys ◽  
Pawel Piwowarczyk ◽  
Magdalena Fijalkowska ◽  
Beata Potrec ◽  
...  

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