scholarly journals Is there still a role for cytotoxic chemotherapy after targeted therapy and immunotherapy in metastatic melanoma? A case report and literature review

2017 ◽  
Vol 36 (1) ◽  
Author(s):  
Aurélien Simon ◽  
Hampig Raphael Kourie ◽  
Joseph Kerger
Keyword(s):  
Case Report ◽  
Targeted Therapy ◽  
Literature Review ◽  
Metastatic Melanoma ◽  
Cytotoxic Chemotherapy

Targeted Therapy in Collecting Duct Carcinoma of the Kidney: A Case Report and Literature Review

2016 ◽  
Vol 14 (2) ◽  
pp. e203-e206 ◽  
Author(s):  
Ming Yin ◽  
Wenge Wang ◽  
Jennifer Rosenberg ◽  
Matthew Kaag ◽  
Monika Joshi ◽  
...  
Keyword(s):  
Case Report ◽  
Targeted Therapy ◽  
Literature Review ◽  
Collecting Duct ◽  
Duct Carcinoma ◽  
Collecting Duct Carcinoma

scholarly journals Apatinib-based targeted therapy against pulmonary sarcomatoid carcinoma: a case report and literature review

Oncotarget ◽  
2018 ◽  
Vol 9 (72) ◽  
pp. 33734-33738 ◽  
Author(s):  
Xiaofeng Li ◽  
Yueming He ◽  
Jinfeng Zhu ◽  
Hongxia Pang ◽  
Yongwei Lin ◽  
...  
Keyword(s):  
Case Report ◽  
Targeted Therapy ◽  
Literature Review ◽  
Sarcomatoid Carcinoma ◽  
Pulmonary Sarcomatoid Carcinoma

Targeted therapy with trastuzumab for advanced salivary ductal carcinoma: case report and literature review

2011 ◽  
Vol 29 (2) ◽  
pp. 704-706 ◽  
Author(s):  
Orit Kaidar-Person ◽  
Salem Billan ◽  
Abraham Kuten
Keyword(s):  
Case Report ◽  
Targeted Therapy ◽  
Literature Review ◽  
Ductal Carcinoma

scholarly journals Potential utilization of neopterin measurements in the assessment of pyrexia in metastatic melanoma treated with combined targeted therapy: a case report

Pteridines ◽  
2020 ◽  
Vol 31 (1) ◽  
pp. 151-157 ◽  
Author(s):  
Marie Bartoušková ◽  
Michaela Hrouzková ◽  
Filip Čtvrtlík ◽  
Pavla Petrová ◽  
Nikol Rušarová ◽  
...  
Keyword(s):  
Case Report ◽  
Targeted Therapy ◽  
Metastatic Melanoma ◽  
Immune Activation ◽  
Checkpoint Inhibitors ◽  
Metastatic Malignant Melanoma ◽  
Marked Rise ◽  
Present Case Report ◽  
Improved Outcomes ◽  
Urinary Neopterin

AbstractIn patients with metastatic melanoma the advent of targeted therapy and immune checkpoint inhibitors has transformed the management of advanced and metastatic disease, resulting in improved outcomes. Neopterin is a biomarker of immune activation increased in cancer as well as in other conditions associated with immune activation. We present a case of a patient with advanced metastatic melanoma responding to the combination targeted therapy with dabrafenib and trametinib. The treatment was complicated by a fever that was accompanied by a marked rise in serum and urinary neopterin concentrations. Present case report illustrates not only the efficacy of combined targeted therapy, but also the utilization of neopterin measurements in the diagnosis and monitoring of pyrexia in patients with metastatic malignant melanoma.

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