scholarly journals Toxic effects of an organophosphate pesticide, envoy 50 SC on the histopathological, hematological, and brain acetylcholinesterase activities in stinging catfish (Heteropneustes fossilis)

2020 ◽  
Vol 81 (1) ◽  
Author(s):  
Rabeya Akter ◽  
Mst Arzu Pervin ◽  
Halima Jahan ◽  
Sharmin Ferdewsi Rakhi ◽  
A. H. M. Mohsinul Reza ◽  
...  
2006 ◽  
Vol 25 (5) ◽  
pp. 397-401 ◽  
Author(s):  
Jiri Kassa ◽  
Daniel Jun ◽  
Kamil Kuca

Russian VX ( O-isobutyl- S-(2-diethylaminoethyl)methylphosphonothioate) is the structural analogue of VX agent. It differs from VX agent ( O-ethyl- S-(2-diisopropylaminoethyl) methylphosphonothioate) by two alkyl groups. The potency of currently available oximes (pralidoxime, obidoxime, HI-6) to reactivate Russian VX–inhibited acetylcholinesterase and to eliminate Russian VX–induced acute toxic effects was evaluated using in vivo methods. In vivo determined percentage of reactivation of Russian VX–inhibited blood and brain acetylcholinesterase in poisoned rats shows that HI-6 seems to be the most efficacious reactivator of Russian VX–inhibited acetylcholinesterase among currently used oximes in the peripheral compartment, whereas no difference between reactivating efficacy of all tested oximes was observed in the central compartment. The oxime HI-6 was also found to be the most efficacious oxime in the elimination of acute lethal toxic effects in Russian VX–poisoned mice among all studied oximes. Thus, the oxime HI-6 seems to be the most suitable oxime for the antidotal treatment of acute poisonings with Russian VX as in the case of VX, sarin, cyclosarin, and soman poisonings.


Pharmacologia ◽  
2015 ◽  
Vol 6 (2) ◽  
pp. 63-72
Author(s):  
Radha Chaube ◽  
Mayank Choubey ◽  
Keerikkattil P. Joy

2013 ◽  
Vol 40 (2) ◽  
pp. 207-212 ◽  
Author(s):  
Mamata Kumari

The effects of the pesticide Abate on the ovary of the cat fish Heteropneustes fossilis (Bloch.) was studied by observing the vitellogenesis of the fish. The LC50 of Abate (0.64 ppm) after 24, 48, 72 and 96 hours of exposure to the fish was determined to be 14.3, 10.0, 6.61 and 5.13 ppm, respectively. The glycogen contents in the normal fish were lowest (6.0 mg/g) and highest (21.96 mg/g) in December and August, respectively; the protein contents were lowest (102.65 mg/g) in August and highest (424.17 mg/g) in December; whereas, the cholesterol was the lowest (9.32 mg/g) in November and highest (15.76 mg/g) in August. In the Abate treated fish, the lowest and highest contents of biochemicals were: 3.58 and 17.10 mg/g of glycogen in December and August, respectively; 80.44 and 378.34 mg/g of protein in December and August, respectively; and 7.15 and 12.92 mg/g of cholesterol in December and August respectively. The results show that the pesticide Abate has the potentiality to alter the vitellogenesis of the fish. DOI: http://dx.doi.org/10.3329/bjz.v40i2.14314 Bangladesh J. Zool. 40(2): 207-212, 2012


2013 ◽  
Vol 14 (3) ◽  
pp. 47-49
Author(s):  
Manjula Saini ◽  
Snehita Chauhan ◽  
P.K. Bajpai

Matured and acclimatized specimens of Heteropneustes fossilis were exposed to 30 ppm cupric chloride. The fish were sacrificed on 15th day of ovaries and were excised out. Histological preparation by the method of OFG staining was studied. Histological observations were observed that there yolk investment appeared cracked and broken due to the treatment with various reagents during paraffin impregnation. The young ova proliferated from stroma appear quite small and without a distinction of core. Most of ova were showed quite thick encapsulation. Vitellogenesis was much pronounced and delayed in liberation of ova was expected.


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