Neuroleptics in the short-term treatment of anorexia nervosa. A double- blind placebo-controlled study with sulpiride

1984 ◽  
Vol 144 (3) ◽  
pp. 288-292 ◽  
Author(s):  
W. Vandereycken
1991 ◽  
Vol 21 (4) ◽  
pp. 991-998 ◽  
Author(s):  
Greg Wilkinson ◽  
Matteo Balestrieri ◽  
Mirella Ruggeri ◽  
Cesario Bellantuono

SYNOPSISMeta-analysis of 19 double-blind placebo-controlled trials of antidepressants (N = 13) and benzodiazepines (N = 6) for patients with panic disorders showed that active treatment had 25% greater success rate than placebo over a mean duration of 14 weeks. There were no statistically significant differences observed between treatment sub-groups (antidepressants – mean duration 16 weeks; and benzodiazepines – mean duration 7 weeks). On this basis antidepressants and benzodiazepines prescribed in clinical settings are likely to be equally effective in the short-term treatment of people with panic disorders.


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