Needle aspiration techniques in preoperative selection of patients with thyroid nodules: a long-term study.

1996 ◽  
Vol 14 (5) ◽  
pp. 1704-1712 ◽  
Author(s):  
A Carpi ◽  
E Ferrari ◽  
M G Toni ◽  
A Sagripanti ◽  
A Nicolini ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
False Negative ◽  
Needle Aspiration ◽  
Long Term Study ◽  
Preoperative Selection ◽  
Pathologic Features ◽  
Term Evaluation ◽  
Selection Of Patients ◽  
Selection Of

PURPOSE Long-term evaluation of the combination of two needle aspiration techniques (NAT) (fine-needle aspiration [FNA] and aspiration needle biopsy [ANB]) in performing an efficient preoperative selection of palpable thyroid nodules. PATIENTS AND METHODS Eight years of extensive use of surgery for the detection of thyroid cancer was compared with 12 years of preoperative selection of by NAT. RESULTS A total of 1,140 operations were performed from 1972 to 1979, and 35 malignant nodules were discovered (3.1%). Five thousand four hundred three patients were examined by NAT from 1980 to 1992; 483 (9%) underwent surgery and 158 malignant nodules were excised. The number of malignant nodules identified by NAT was 166 (eight were not excised) (3.1% of the total population examined). The principal clinical and pathologic features were similar in both groups. ANB yielded a definite benign diagnosis in 88 patients with inadequate FNA findings, it correctly identified four malignant nodules diagnosed as benign by FNA, it showed a macrofollicular component in 115 nodules diagnosed by FNA as microfollicular nodules, and it significantly changed the predictive value of 79 suspicions FNA diagnoses. CONCLUSION Introduction of NAT reduced the number of operations for palpable thyroid nodules from 143 to 40 per year and increased from four to 13 the number of malignant nodules excised without any change in the overall incidence of malignant nodules. The combination of ANB to FNA significantly contributed to the high and efficient preoperative patient selection, principally by reducing the number of indeterminate or suspicious, as well as false-negative, preoperative FNA diagnoses.

Aspiration Needle Biopsy in Preoperative Selection of Thyroid Nodules Defined at Fine-Needle Aspiration as Microfollicular Lesions

1999 ◽  
Vol 22 (1) ◽  
pp. 65-69 ◽  
Author(s):  
Angelo Carpi ◽  
Fabrizio Menchini Fabris ◽  
Elisa Ferrari ◽  
Andrea Sagripanti ◽  
Andrea Nicolini ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Needle Biopsy ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Preoperative Selection ◽  
Selection Of

Large needle aspiration biopsy histology for preoperative selection of Hürthle cell thyroid nodules

2011 ◽  
Vol 59 (5) ◽  
pp. 892-896 ◽  
Author(s):  
Angelo Carpi ◽  
Giuseppe Rossi ◽  
Jeffrey I Mechanick ◽  
Andrea Nicolini ◽  
Marcello Camici ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Hürthle Cell ◽  
Preoperative Selection ◽  
Needle Aspiration Biopsy ◽  
Selection Of

Pediatric Thyroid Nodules: Disease Demographics and Clinical Management as Determined by Fine Needle Aspiration Biopsy

PEDIATRICS ◽  
1995 ◽  
Vol 95 (1) ◽  
pp. 46-49
Author(s):  
Stephen S. Raab ◽  
Jan F. Silverman ◽  
Tarik M. Elsheikh ◽  
Patricia A. Thomas ◽  
Paul E. Wakely
Keyword(s):  
Fine Needle Aspiration ◽  
Thyroid Nodules ◽  
Fine Needle Aspiration Biopsy ◽  
False Negative ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Benign Nodule ◽  
Fine Needle ◽  
Minimal Invasiveness ◽  
Needle Aspiration Biopsy

Objective. The prevalence of thyroid nodularity in children has been estimated to be 1.8%. The reported prevalence of specific diseases which comprise these nodules is conflicting as evidenced by a reported range of malignancy of 2 to 50% in solitary nodules. In order to better classify pediatric (<18 years old) thyroid disease and evaluate the utility of fine needle aspiration biopsy (FNAB) in this patient population, we retrospectively reviewed 66 FNABs from 64 thyroid nodules and 2 perithyroid lymph nodes from 57 patients. Methodology. Patients: The study was composed of 8 males and 49 females who ranged in age from 1 to 18 years old (mean = 13.1). Design: Surgical and/or clinical follow-up was obtained in all patients. The 66 FNAB diagnoses were initially classified into specific diseases. However, for the purpose of this review, the cases were classified as: 3 insufficient, 51 benign, 8 suspicious, and 4 malignant. Results. There were no "false positives" and one "false negative" (a papillary carcinoma was misdiagnosed as a benign nodule). Overall, 10 patients (18%) had malignant thyroid lesions, including 8 papillary carcinomas and 2 follicular carcinomas. Benign diagnoses included benign nodule, cyst, lymphocytic thyroiditis, granulomatous thyroiditis, hyperplasia, and abscess. Conclusions. The prevalence of malignancy in pediatric patients with thyroid nodules was 18%. We conclude that, because of its high diagnostic accuracy and minimal invasiveness, FNAB is useful in the management of pediatric thyroid nodules.

scholarly journals Active surveillance in patients with a PSA >10 ng/mL

2014 ◽  
Vol 8 (9-10) ◽  
pp. 702 ◽  
Author(s):  
Paul Toren ◽  
Lih-Ming Wong ◽  
Narhari Timilshina ◽  
Shabbir Alibhai ◽  
John Trachtenberg ◽  
...  
Keyword(s):  
Active Surveillance ◽  
Specific Antigen ◽  
Sufficient Evidence ◽  
Hazard Ratios ◽  
Diagnostic Biopsy ◽  
Selection Of Patients ◽  
Baseline Psa ◽  
Selection Of

Introduction: The use of prostate-specific antigen (PSA) in active surveillance (AS) for prostate cancer is controversial. Some consider it an unreliable marker and others as sufficient evidence to exclude patients from AS. We analyzed our cohort of AS patients with a PSA over 10 ng/mL.Methods: We included patients who had clinical T1c–T2a Gleason ≤6 disease, and ≤3 positive cores with ≤50% core involvement at diagnostic biopsy and ≥2 total biopsies. Patients were divided into 3 groups: (1) those with baseline PSA >10 ng/mL, (2) those with a PSA rise >10 ng/mL during follow-up; and (3) those with a PSA <10 ng/mL throughout AS. Adverse histology was defined as biopsy parameters exceeding the entry criteria limits. We further compared this cohort to a concurrent institutional cohort with equal biopsy parameters treated with immediate radical prostatectomy.Results: Our cohort included 698 patients with a median follow-up of 46.2 months. In total, 82 patients had a baseline PSA >10 ng/mL and 157 had a PSA rise >10 ng/mL during surveillance. No difference in adverse histology incidence was detected between groups (p = 0.3). Patients with a PSA greater than 10 were older and had higher prostate volumes. Hazard ratios for groups with a PSA >10 were protective against adverse histology. Larger prostate volume and minimal core involvement appear as factors related to this successful selection of patients to be treated with AS.Conclusion: These results suggest that a strict cut-off PSA value for all AS patients is unwarranted and may result in overtreatment. Though lacking long-term data and validation, AS appears safe in select patients with a PSA >10 ng/mL and low volume Gleason 6 disease.

scholarly journals Changing trends in the management of corpus luteum haemorrhage

2021 ◽  
Vol 10 (8) ◽  
pp. 3261
Author(s):  
Avantika Gupta ◽  
Deepthi Nayak ◽  
Purnima Tiwari
Keyword(s):  
Corpus Luteum ◽  
Conservative Management ◽  
Risk Group ◽  
Massive Bleeding ◽  
High Risk Group ◽  
Changing Trends ◽  
Oxygen Carrying Capacity ◽  
Selection Of Patients ◽  
Selection Of

Corpus luteal haemorrhage usually causes only mild symptoms and resolve spontaneously, however, it can cause massive bleeding in certain patients with coagulation or bleeding disorders. Over a decade, the management of corpus luteum haemorrhage has shifted from surgical to conservative management. This article focuses on selection of patients for conservative management so that the morbidities associated with the surgery can be avoided. Conservative management includes optimization of oxygen carrying capacity of blood, correction of coagulopathy and appropriate analgesia. It can be recurrent in certain high-risk group of patients who will need long term suppression of ovulation.

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