Better survival with epidermal growth factor receptor exon 19 deletion than with exon 21 mutation in gefitinib-treated non-small cell lung cancer patients is due to differential inhibition of downstream signals

J. Zhu; Y. Wu; W. Zhong; G. Zhang; R. Li; X. Zhang; A. Guo; Y. Zhang; S. An; T. S. Mok

doi:10.1200/jco.2008.26.15_suppl.14501

Better survival with epidermal growth factor receptor exon 19 deletion than with exon 21 mutation in gefitinib-treated non-small cell lung cancer patients is due to differential inhibition of downstream signals

Journal of Clinical Oncology ◽

10.1200/jco.2008.26.15_suppl.14501 ◽

2008 ◽

Vol 26 (15_suppl) ◽

pp. 14501-14501

Author(s):

J. Zhu ◽

Y. Wu ◽

W. Zhong ◽

G. Zhang ◽

R. Li ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor Receptor ◽

Small Cell ◽

Differential Inhibition ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Exon 19 Deletion ◽

Epidermal Growth ◽

Exon 19

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Faculty Opinions recommendation of Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14705.472219 ◽

2006 ◽

Author(s):

Nicola Normanno

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Deletion Mutations ◽

Lung Cancer Patients ◽

Exon 19 Deletion ◽

Epidermal Growth ◽

Exon 19

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Exon 19 Deletion Mutations of Epidermal Growth Factor Receptor Are Associated with Prolonged Survival in Non–Small Cell Lung Cancer Patients Treated with Gefitinib or Erlotinib

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-06-0462 ◽

2006 ◽

Vol 12 (13) ◽

pp. 3908-3914 ◽

Cited By ~ 384

Author(s):

David M. Jackman ◽

Beow Y. Yeap ◽

Lecia V. Sequist ◽

Neal Lindeman ◽

Alison J. Holmes ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Deletion Mutations ◽

Lung Cancer Patients ◽

Exon 19 Deletion ◽

Epidermal Growth ◽

Exon 19

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Exon 19 deletion of epidermal growth factor receptor is associated with prolonged survival in brain metastases from non-small-cell lung cancer

Tumor Biology ◽

10.1007/s13277-015-3653-2 ◽

2015 ◽

Vol 36 (12) ◽

pp. 9251-9258 ◽

Cited By ~ 3

Author(s):

Hongwei Li ◽

Xiaqin Zhang ◽

Jianzhong Cao ◽

Pengcheng Su ◽

Jianhong Lian ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Exon 19 Deletion ◽

Epidermal Growth ◽

Exon 19

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The different efficacy of gefitinib or erlotinib according to epidermal growth factor receptor exon 19 and exon 21 mutations in Korean non-small cell lung cancer patients

Journal of Cancer Research and Clinical Oncology ◽

10.1007/s00432-010-0928-2 ◽

2010 ◽

Vol 137 (4) ◽

pp. 687-694 ◽

Cited By ~ 19

Author(s):

Jong-Mu Sun ◽

Young-Woong Won ◽

Seung Tae Kim ◽

Jung Hoon Kim ◽

Yoon-La Choi ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Epidermal Growth ◽

Exon 19

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Comparison of Clinical Outcomes Following Gefitinib and Erlotinib Treatment in Non–Small-Cell Lung Cancer Patients Harboring an Epidermal Growth Factor Receptor Mutation in Either Exon 19 or 21

Journal of Thoracic Oncology ◽

10.1097/jto.0000000000000095 ◽

2014 ◽

Vol 9 (4) ◽

pp. 506-511 ◽

Cited By ~ 35

Author(s):

Sung Hee Lim ◽

Ji Yun Lee ◽

Jong-Mu Sun ◽

Jin Seok Ahn ◽

Keunchil Park ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Epidermal Growth ◽

Exon 19

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Erratum to: Exon 19 deletion of epidermal growth factor receptor is associated with prolonged survival in brain metastases from non-small-cell lung cancer

Tumor Biology ◽

10.1007/s13277-015-3953-6 ◽

2015 ◽

Vol 36 (9) ◽

pp. 7333-7334

Author(s):

Hongwei Li ◽

Xiaqin Zhang ◽

Jianzhong Cao ◽

Pengcheng Su ◽

Jianhong Lian ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Exon 19 Deletion ◽

Epidermal Growth ◽

Exon 19

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Real-World Treatment Patterns, Epidermal Growth Factor Receptor (EGFR) Testing and Outcomes in EGFR-Mutated Advanced Non-small Cell Lung Cancer Patients in Belgium: Results from the REVEAL Study

Drugs - Real World Outcomes ◽

10.1007/s40801-021-00243-w ◽

2021 ◽

Author(s):

Kristof Cuppens ◽

◽

Liesbet Lodewyckx ◽

Ingel Demedts ◽

Lore Decoster ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor Receptor ◽

Treatment Patterns ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Reveal Study ◽

Epidermal Growth ◽

Egfr Mutated

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Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression.

Oncology Reports ◽

10.3892/or.7.3.603 ◽

2000 ◽

Cited By ~ 13

Author(s):

Y Ohsaki ◽

S Tanno ◽

Y Fujita ◽

E Toyoshima ◽

S Fujiuchi ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Poor Prognosis ◽

Growth Factor Receptor ◽

Small Cell ◽

Receptor Expression ◽

Small Cell Lung ◽

P53 Overexpression ◽

Lung Cancer Patients ◽

Epidermal Growth

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Objective regressions in non-small cell lung cancer patients treated in Phase I trials of oral ZD1839 (IressaTM), a selective tyrosine kinase inhibitor that blocks the epidermal growth factor receptor (EGFR)

Lung Cancer ◽

10.1016/s0169-5002(00)80233-0 ◽

2000 ◽

Vol 29 (1) ◽

pp. 72 ◽

Cited By ~ 34

Author(s):

M.G Kris ◽

R Herbst ◽

D Rischin ◽

P LoRusso ◽

J Baselga ◽

...

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Small Cell ◽

Phase I Trials ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Epidermal Growth

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Phosphorylation, But Not Overexpression, of Epidermal Growth Factor Receptor Is Associated With Poor Prognosis of Non-Small Cell Lung Cancer Patients

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics ◽

10.3727/096504003108748348 ◽

2003 ◽

Vol 13 (5) ◽

pp. 289-298 ◽

Cited By ~ 52

Author(s):

Takanori Kanematsu ◽

Seiji Yano ◽

Hisanori Uehara ◽

Yoshimi Bando ◽

Saburo Sone

Keyword(s):

Lung Cancer ◽

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Poor Prognosis ◽

Growth Factor Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Lung Cancer Patients ◽

Epidermal Growth

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