Factors Influencing the Kinetics of Solute Release

2017 ◽  
pp. 37-154 ◽  
Author(s):  
Wei-Youh Kuu ◽  
Ray W. Wood ◽  
Theodore J. Roseman
Methods ◽  
1998 ◽  
Vol 16 (1) ◽  
pp. 105-116 ◽  
Author(s):  
Edward K. Wagner ◽  
Matthew D. Petroski ◽  
Nupur T. Pande ◽  
Pauline T. Lieu ◽  
Marcia Rice

2001 ◽  
Vol 34 (5) ◽  
pp. 431-440 ◽  
Author(s):  
S Tajchakavit ◽  
J.I Boye ◽  
D Bélanger ◽  
R Couture

2019 ◽  
Vol 116 ◽  
pp. 113-119 ◽  
Author(s):  
Frank Bullerjahn ◽  
Maciej Zajac ◽  
Mohsen Ben Haha ◽  
Karen L. Scrivener

2011 ◽  
Vol 25 (9) ◽  
pp. 4106-4112 ◽  
Author(s):  
Jitendra Kumar Satyarthi ◽  
Sambhu Radhakrishnan ◽  
Darbha Srinivas

1974 ◽  
Vol 8 (9) ◽  
pp. 512-519 ◽  
Author(s):  
John A. Romankiewicz

Pyelonephritis is often considered a benign disease, yet in some studies as high as 35 percent of the cases progressed to severe renal disease. Treatment failures occur because of relapse of infection, emergence of secondary infecting organisms, re-infection and the development of antibiotic resistance. In addition, inadequate renal tissue concentrations of antibiotics account for a majority of treatment failures. The factors which influence diffusion of antibiotics into renal tissues are discussed. The importance of renal medullary tissue levels of antibiotics is emphasized, as well as the influence that protein binding, non-ionic diffusion and the state of hydration have on these levels. Distribution kinetics of sulfisoxazole, ampicillin, tetracyclines, cephalosporins, nalidixic acid, nitrofurantoin, gentamicin, carbenicillin indanyl sodium, sulfamethoxazole and trimethoprim as they relate to the treatment of pyelonephritis are also presented.


1977 ◽  
Vol 162 (1) ◽  
pp. 147-156 ◽  
Author(s):  
J D McGivan ◽  
N M Bradford ◽  
A D Beavis

1. The characteristics of ornithine catabolism by the aminotransferase pathway in isolated mitochondria were determined. 2. Ornithine synthesis from glutamate and glutamate gamma-semialdehyde produced by the oxidation of proline was studied. No ornithine was formed in the absence of rotenone. 3. The mechanism of ornithine transport was reinvestigated, and the existence of an ornithine+/H+ exchange system postulated. 4. The kinetics of ornithine transport, ornithine catabolism in intact mitochondria and ornithine aminotransferase activity in solubilized mitochondria were compared. It is concluded that ornithine aminotransferase activity in liver mitochondria is rate-limited by the transport of ornithine across the mitochondrial membrane, and that this enzyme is involved primarily in ornithine degradation rather than ornithine synthesis.


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