Model-Based Integration for Clinical Trial Simulation and Design: A Phase II Case Study for Naratriptan

Simulation for Designing Clinical Trials ◽

10.1201/9780203910276-20 ◽

2002 ◽

pp. 331-344

Keyword(s):

Clinical Trial ◽

Phase Ii ◽

Clinical Trial Simulation ◽

Model Based ◽

Trial Simulation

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Predicting the Outcome of Phase III Trials using Phase II Data: A Case Study of Clinical Trial Simulation in Late Stage Drug Development

Basic & Clinical Pharmacology & Toxicology ◽

10.1111/j.1742-7843.2005.pto960314.x ◽

2005 ◽

Vol 96 (3) ◽

pp. 235-241 ◽

Author(s):

Filip De Ridder

Keyword(s):

Clinical Trial ◽

Drug Development ◽

Phase Ii ◽

Phase Iii ◽

Clinical Trial Simulation ◽

Trial Simulation ◽

Phase Iii Trials

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Clinical Trial Simulation—A Case Study Incorporating Efficacy and Tolerability Dose Response

Statistics for Biology and Health - Dose Finding in Drug Development ◽

10.1007/0-387-33706-7_8 ◽

2006 ◽

pp. 106-126

Author(s):

Wayne Ewy ◽

Peter Lockwood ◽

Candace Bramson

Keyword(s):

Clinical Trial ◽

Dose Response ◽

Clinical Trial Simulation ◽

Trial Simulation

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Combining Model‐Based Clinical Trial Simulation, Pharmacoeconomics, and Value of Information to Optimize Trial Design

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12579 ◽

2020 ◽

Author(s):

Daniel Hill‐McManus ◽

Dyfrig A. Hughes

Keyword(s):

Clinical Trial ◽

Value Of Information ◽

Trial Design ◽

Clinical Trial Simulation ◽

Model Based ◽

Trial Simulation

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Abstract 3176: Biomarker identification using xenograft mouse model based clinical trial simulation and artificial intelligence data analytics

10.1158/1538-7445.sabcs18-3176 ◽

2019 ◽

Author(s):

M Afshar ◽

Francis Bichat ◽

Olivier Duchamp ◽

A Etcheto ◽

Damien France ◽

...

Keyword(s):

Artificial Intelligence ◽

Clinical Trial ◽

Mouse Model ◽

Data Analytics ◽

Clinical Trial Simulation ◽

Biomarker Identification ◽

Xenograft Mouse Model ◽

Model Based ◽

Trial Simulation

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The Rheumatoid Arthritis Drug Development Model: a case study in Bayesian clinical trial simulation

Pharmaceutical Statistics ◽

10.1002/pst.368 ◽

2009 ◽

pp. n/a-n/a ◽

Author(s):

Richard M. Nixon ◽

Anthony O'Hagan ◽

Jeremy Oakley ◽

Jason Madan ◽

John W. Stevens ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Clinical Trial ◽

Drug Development ◽

Development Model ◽

Clinical Trial Simulation ◽

Trial Simulation

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Abstract 3176: Biomarker identification using xenograft mouse model based clinical trial simulation and artificial intelligence data analytics

10.1158/1538-7445.am2019-3176 ◽

2019 ◽

Author(s):

M Afshar ◽

Francis Bichat ◽

Olivier Duchamp ◽

A Etcheto ◽

Damien France ◽

...

Keyword(s):

Artificial Intelligence ◽

Clinical Trial ◽

Mouse Model ◽

Data Analytics ◽

Clinical Trial Simulation ◽

Biomarker Identification ◽

Xenograft Mouse Model ◽

Model Based ◽

Trial Simulation

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Misclassification and discordance of measured blood pressure from patient’s true blood pressure in current clinical practice: a clinical trial simulation case study

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-012-9250-8 ◽

2012 ◽

Vol 39 (3) ◽

pp. 283-294 ◽

Author(s):

Yuyan Jin ◽

Robert Bies ◽

Marc R. Gastonguay ◽

Norman Stockbridge ◽

Jogarao Gobburu ◽

...

Keyword(s):

Blood Pressure ◽

Clinical Trial ◽

Clinical Practice ◽

Clinical Trial Simulation ◽

Current Clinical Practice ◽

Trial Simulation ◽

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A method to assess congruence of a clinical trial simulation (CTS) and a phase II clinical study

Clinical Pharmacology & Therapeutics ◽

10.1016/s0009-9236(99)80272-0 ◽

1999 ◽

Vol 65 (2) ◽

pp. 185-185

Author(s):

P MUDDJR ◽

M HALE ◽

Y SHEN ◽

R OCONNORSEMMES ◽

M SALE

Keyword(s):

Clinical Trial ◽

Clinical Study ◽

Phase Ii ◽

Clinical Trial Simulation ◽

Trial Simulation ◽

Phase Ii Clinical Study

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Development of a Model‐based Clinical Trial Simulation Platform to Optimize the Design of Clinical Trials for Duchenne Muscular Dystrophy

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12753 ◽

2021 ◽

Author(s):

Karthik Lingineni ◽

Varun Aggarwal ◽

Juan Francisco Morales ◽

Daniela J Conrado ◽

Diane Corey ◽

...

Keyword(s):

Clinical Trial ◽

Clinical Trials ◽

Duchenne Muscular Dystrophy ◽

Muscular Dystrophy ◽

Clinical Trial Simulation ◽

Simulation Platform ◽

Model Based ◽

Trial Simulation

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Model-Based Integration for Clinical Trial Simulation and Design

Drugs and the Pharmaceutical Sciences - Simulation for Designing Clinical Trials ◽

10.1201/9780203910276.ch16 ◽

2002 ◽

Author(s):

Gordon Graham ◽

Leon Aarons ◽

Ivan Nestorov ◽

Stephen Duffull

Keyword(s):

Clinical Trial ◽

Clinical Trial Simulation ◽

Model Based ◽

Trial Simulation

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