Physiologically Based Absorption Modeling to Explore the Impact of Food and Gastric pH Changes on the Pharmacokinetics of Alectinib

Physiologically Based Absorption Modelling to Explore the Impact of Food and Gastric pH Changes on the Pharmacokinetics of Entrectinib

The AAPS Journal ◽

10.1208/s12248-020-00463-y ◽

2020 ◽

Vol 22 (4) ◽

Cited By ~ 1

Author(s):

Neil Parrott ◽

Cordula Stillhart ◽

Marc Lindenberg ◽

Bjoern Wagner ◽

Karey Kowalski ◽

...

Keyword(s):

Gastric Ph ◽

Ph Changes ◽

Physiologically Based ◽

Maximizing the Impact of Physiologically Based Oral Absorption Modeling and Simulation

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2016.11.015 ◽

2017 ◽

Vol 106 (3) ◽

pp. 734-737 ◽

Cited By ~ 2

Author(s):

John I. Chung ◽

Ron C. Kelly ◽

Jan Wahlstrom ◽

Benjamin Wu ◽

Tian Wu ◽

...

Keyword(s):

Modeling And Simulation ◽

Oral Absorption ◽

Physiologically Based ◽

Absorption Modeling ◽

Utility of Physiologically Based Pharmacokinetic Absorption Modeling to Predict the Impact of Salt-to-Base Conversion on Prasugrel HCl Product Bioequivalence in the Presence of Proton Pump Inhibitors

The AAPS Journal ◽

10.1208/s12248-017-0116-2 ◽

2017 ◽

Vol 19 (5) ◽

pp. 1479-1486 ◽

Cited By ~ 7

Author(s):

Jianghong Fan ◽

Xinyuan Zhang ◽

Liang Zhao

Keyword(s):

Proton Pump Inhibitors ◽

Proton Pump ◽

Physiologically Based ◽

Absorption Modeling ◽

Evaluating the impact of physiological properties of the gastrointestinal tract on drug in vivo performance using Physiologically Based Biopharmaceutics Modeling and virtual clinical trials

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2021.04.007 ◽

2021 ◽

Author(s):

Rebeka Jereb ◽

Jerneja Opara ◽

Aleksander Bajc ◽

Boštjan Petek

Keyword(s):

Clinical Trials ◽

Gastrointestinal Tract ◽

Physiological Properties ◽

Physiologically Based ◽

Analysis of the impact of controlled release formulations on oral drug absorption, gut wall metabolism and relative bioavailability of CYP3A substrates using a physiologically-based pharmacokinetic model

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2014.10.018 ◽

2015 ◽

Vol 67 ◽

pp. 32-44 ◽

Cited By ~ 14

Author(s):

Andrés Olivares-Morales ◽

Yoshiteru Kamiyama ◽

Adam S. Darwich ◽

Leon Aarons ◽

Amin Rostami-Hodjegan

Keyword(s):

Controlled Release ◽

Drug Absorption ◽

Pharmacokinetic Model ◽

Relative Bioavailability ◽

Oral Drug ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based ◽

Controlled Release Formulations ◽

Utility of Physiologically Based Absorption Modeling in Implementing Quality by Design in Drug Development

The AAPS Journal ◽

10.1208/s12248-010-9250-9 ◽

2011 ◽

Vol 13 (1) ◽

pp. 59-71 ◽

Cited By ~ 81

Author(s):

Xinyuan Zhang ◽

Robert A. Lionberger ◽

Barbara M. Davit ◽

Lawrence X. Yu

Keyword(s):

Drug Development ◽

Quality By Design ◽

Physiologically Based ◽

Absorption Modeling

The impact of gastric pH, volume, and emptying on the food effect of ziprasidone oral absorption

The AAPS Journal ◽

10.1208/s12248-017-0065-9 ◽

2017 ◽

Vol 19 (4) ◽

pp. 1084-1090 ◽

Cited By ~ 14

Author(s):

Steven C Sutton ◽

Richard Nause ◽

Kuan Gandelman

Keyword(s):

Oral Absorption ◽

Food Effect ◽

Gastric Ph ◽

Biopharmaceutics Applications of Physiologically Based Pharmacokinetic Absorption Modeling and Simulation in Regulatory Submissions to the U.S. Food and Drug Administration for New Drugs

The AAPS Journal ◽

10.1208/s12248-021-00564-2 ◽

2021 ◽

Vol 23 (2) ◽

Author(s):

Fang Wu ◽

Heta Shah ◽

Min Li ◽

Peng Duan ◽

Ping Zhao ◽

...

Keyword(s):

Modeling And Simulation ◽

Drug Administration ◽

Food And Drug Administration ◽

New Drugs ◽

Physiologically Based ◽

Regulatory Submissions ◽

Absorption Modeling ◽

The U.S

Impact of differential particle size of fenofibrate nanosuspensions on biopharmaceutical performance using physiologically based absorption modeling in rats

Journal of Drug Delivery Science and Technology ◽

10.1016/j.jddst.2020.102040 ◽

2020 ◽

Vol 60 ◽

pp. 102040

Author(s):

Divisha Jain ◽

Poonam Singh Thakur ◽

Samarth D. Thakore ◽

Sanjaya K. Samal ◽

Arvind K. Bansal

Keyword(s):

Particle Size ◽

Physiologically Based ◽

Absorption Modeling

The Impact of Exercise and Intersubject Variability on Dose Estimates for Dichloromethane Derived from a Physiologically Based Pharmacokinetic Model

Fundamental and Applied Toxicology ◽

10.1006/faat.1994.1003 ◽

1994 ◽

Vol 22 (1) ◽

pp. 20-25 ◽

Cited By ~ 20

Author(s):

D Dankovic

Keyword(s):

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Intersubject Variability ◽

Physiologically Based ◽