scholarly journals A Quantitative Trait Locus on Chromosome 6 Regulates the Onset of Puberty in Mice

Endocrinology ◽  
2006 ◽  
Vol 147 (11) ◽  
pp. 5132-5138 ◽  
Author(s):  
Brandon M. Nathan ◽  
Craig A. Hodges ◽  
Pamela J. Supelak ◽  
Lindsay C. Burrage ◽  
Joseph H. Nadeau ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Quantitative Trait ◽  
Chromosome 6 ◽  
Trait Locus

The consequences of carrying the Booroola fecundity (FecB) gene on sheep liveweight

2000 ◽  
Vol 2000 ◽  
pp. 43-43 ◽  
Author(s):  
G.A. Walling ◽  
K.G. Dodds ◽  
S.M. Galloway ◽  
A.E. Beattie ◽  
E.A. Lord ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Quantitative Trait ◽  
Personal Communication ◽  
Pleiotropic Effect ◽  
Ovulation Rate ◽  
Chromosome 6 ◽  
Sheep Chromosome ◽  
Trait Locus ◽  
Fertility Traits

The increase in ovulation rate caused by the Booroola gene was first observed in the Booroola Merino strain of sheep (Davis et al., 1982) and the gene was subsequently mapped to sheep chromosome 6 (OOV6) (Montgomery et al. 1994). The low heritability of fertility traits and the desire to produce more lambs per ewe from meat breeds has lead to many crossbreeding programs seeking to obtain the benefits of the Booroola gene. However, many producers report animals carrying a Booroola allele to be lighter than non-carriers (G. Davis, personal communication). The Booroola Merino strain of sheep is typically lighter than recipient breeds used in the introgression programmes e.g. Romney. This study aims to determine whether the Booroola gene has a pleiotropic effect on liveweight or whether there is any evidence to suggest a closely linked quantitative trait locus (QTL) affecting liveweight that may ‘hitchhike’ with the Booroola gene.

scholarly journals Mapping of a Milk Production Quantitative Trait Locus to a 420-kb Region on Bovine Chromosome 6

Genetics ◽  
2004 ◽  
Vol 169 (1) ◽  
pp. 275-283 ◽  
Author(s):  
Hanne Gro Olsen ◽  
Sigbjørn Lien ◽  
Mathieu Gautier ◽  
Heidi Nilsen ◽  
Arne Roseth ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Milk Production ◽  
Quantitative Trait ◽  
Bovine Chromosome ◽  
Chromosome 6 ◽  
Trait Locus

scholarly journals Quantitative trait locus mapping of airway responsiveness to chromosomes 6 and 7 in inbred mice

1999 ◽  
Vol 277 (6) ◽  
pp. L1118-L1123 ◽  
Author(s):  
G. T. De Sanctis ◽  
J. B. Singer ◽  
A. Jiao ◽  
C. N. Yandava ◽  
Y. H. Lee ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Qtl Mapping ◽  
Quantitative Trait ◽  
Genetic Factors ◽  
Inbred Mice ◽  
Airway Responsiveness ◽  
Chromosome 17 ◽  
Chromosome 6 ◽  
Trait Locus ◽  
Locus Mapping

Quantitative trait locus (QTL) mapping was used to identify chromosomal regions contributing to airway hyperresponsiveness in mice. Airway responsiveness to methacholine was measured in A/J and C3H/HeJ parental strains as well as in progeny derived from crosses between these strains. QTL mapping of backcross [(A/J × C3H/HeJ) × C3H/HeJ] progeny ( n = 137–227 informative mice for markers tested) revealed two significant linkages to loci on chromosomes 6 and 7. The QTL on chromosome 6 confirms the previous report by others of a linkage in this region in the same genetic backgrounds; the second QTL, on chromosome 7, represents a novel locus. In addition, we obtained suggestive evidence for linkage (logarithm of odds ratio = 1.7) on chromosome 17, which lies in the same region previously identified in a cross between A/J and C57BL/6J mice. Airway responsiveness in a cross between A/J and C3H/HeJ mice is under the control of at least two major genetic loci, with evidence for a third locus that has been previously implicated in an A/J and C57BL/6J cross; this indicates that multiple genetic factors control the expression of this phenotype.

Two-loci interaction confirms arthritis-regulating quantitative trait locus on rat chromosome 6

Genomics ◽  
2003 ◽  
Vol 82 (6) ◽  
pp. 652-659 ◽  
Author(s):  
Peter Olofsson ◽  
Patrik Wernhoff ◽  
Jens Holmberg ◽  
Rikard Holmdahl
Keyword(s):  
Quantitative Trait Locus ◽  
Quantitative Trait ◽  
Chromosome 6 ◽  
Trait Locus

Quantitative trait locus for reading disability on chromosome 6

Science ◽  
1994 ◽  
Vol 266 (5183) ◽  
pp. 276-279 ◽  
Author(s):  
L. Cardon ◽  
S. Smith ◽  
D. Fulker ◽  
W. Kimberling ◽  
B. Pennington ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Reading Disability ◽  
Quantitative Trait ◽  
Chromosome 6 ◽  
Trait Locus
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