Glucose, growth hormone, cortisol, and insulin responses to glucagon injection in normal infants, aged 0.5-12 months

1995 ◽  
Vol 80 (10) ◽  
pp. 3032-3035 ◽  
Author(s):  
J. P. Chanoine
Keyword(s):  
Growth Hormone ◽  
Glucagon Injection ◽  
Insulin Responses

PLASMA INSULIN AND GROWTH HORMONE CONCENTRATIONS IN PREGNANT SHEEP I:

1976 ◽  
Vol 82 (2) ◽  
pp. 544-552 ◽  
Author(s):  
Knut Hove ◽  
Anne Kristine Blom
Keyword(s):  
Growth Hormone ◽  
Plasma Insulin ◽  
Late Pregnancy ◽  
Plasma Growth Hormone ◽  
Energy Substrate ◽  
Insulin Levels ◽  
Pregnant Sheep ◽  
Plasma Insulin Levels ◽  
Insulin Responses ◽  
Substrate Concentrations

ABSTRACT Two or three foetal lambs regularly result in a varying degree of carbohydrate shortage in mother ewes in late pregnancy. We have investigated the correlation between plasma insulin, growth hormone and energy substrate concentrations in ewes 8 and 1 weeks before lambing. Plasma growth hormone was fairly constant (2–3 ng/ml) throughout the 24-h cycle 8 weeks before parturition. Seven weeks later higher average levels and increased diurnal fluctuations were observed in 3 out of 4 multiparous ewes. The average post-absorptive insulin levels were reduced by 50 per cent during the same interval. Simultaneously decreased post-absorptive sugar and increased acetoacetate levels were observed. It is concluded that the hormonal adaptations to the increasing carbohydrate deficit in late pregnancy, especially among multiparous ewes, include: a) reduced post-absorptive plasma insulin levels, b) reduced insulin responses to feeding, and c) increased levels of growth hormone in the plasma.

Effect of propionate infusion on plasma glucagon, insulin and growth hormone concentrations in lactating dairy cows

1985 ◽  
Vol 109 (3) ◽  
pp. 348-354 ◽  
Author(s):  
J. L. Sartin ◽  
K. A. Cummins ◽  
R.J. Kemppainen ◽  
R. Carnes ◽  
D. G. McClary ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Dairy Cows ◽  
Plasma Concentrations ◽  
Energy Partitioning ◽  
Early Lactation ◽  
Plasma Glucagon ◽  
Metabolic Hormones ◽  
Lactating Dairy Cows ◽  
Nutrient Partitioning ◽  
Insulin Responses

Abstract. Altered concentrations of metabolic hormones have been suggested as important mediators of energy partitioning during early lactation. This study was initiated to determine the effects of propionate (1.0 mmol/kg body weight) infusion on plasma concentrations of glucagon, insulin, growth hormone, propionate and glucose at 14 days ante-partum (AP) and days 5 and 30 postpartum (PP). No differences were seen in propionate concentrations between sampling days. Glucose concentrations were elevated following propionate infusion in pregnant cows but were not elevated in the PP cows. Insulin responses to propionate infusion did not differ between days while the glucagon response was blunted at day 5 PP. Basal glucagon concentrations were elevated between days 5 and 30 PP, insulin concentrations were unchanged between days, while the molar insulin/glucagon ratio was decreased during early lactation. Basal growth hormone (GH) concentrations were elevated between day 14 AP and day 30 PP. GH responsiveness to declining propionate concentrations was greatest at day 5 PP. These data further suggest a role for glucagon as well as GH in nutrient partitioning during early lactation.

Effect of Aminophylline on Growth Hormone and Insulin Responses to Arginine in Normal Subjects

1975 ◽  
Vol 7 (05) ◽  
pp. 437-438
Author(s):  
M. Peracchi ◽  
F. Cavagnini ◽  
M. Pinto ◽  
P. Bulgheroni ◽  
A. Panerai
Keyword(s):  
Growth Hormone ◽  
Normal Subjects ◽  
Insulin Responses

PLASMA INSULIN RESPONSE DURING ORAL GLUCOSE TOLERANCE TESTS IN NEWBORNS OF NORMAL AND GESTATIONAL DIABETIC MOTHERS

PEDIATRICS ◽  
1969 ◽  
Vol 44 (1) ◽  
pp. 76-83
Author(s):  
Rosita S. Pildes ◽  
Robert J. Hart ◽  
Richard Warrner ◽  
Marvin Cornblath
Keyword(s):  
Growth Hormone ◽  
Blood Glucose ◽  
Plasma Insulin ◽  
Insulin Response ◽  
Sampling Interval ◽  
Oral Glucose ◽  
Glucose Tolerance Tests ◽  
Fasting Plasma Insulin ◽  
Insulin Responses ◽  
Diabetic Mothers

The plasma insulin, growth hormone, free fatty acids (FFA), and blood glucose responses to the oral ingestion of glucose were studied in eight infants of gestational diabetic mothers (IGDM) and in 11 normal newborns during the first 24 hours of life. Fasting blood sugars and growth hormone values were similar in the IGDM and the normal. Fasting plasma insulin values were significantly higher (14 ± 2 µU/ml) in the IGDM than those in the normal (7 ± 1 µU/ml), and FFA values were significantly lower (1268 ± 42 µEq/l versus 1627 ± 155 µEq/l). Blood glucose values at each sampling interval after the ingestion of glucose were significantly lower in the IGDM than those in the normal. Plasma insulin responses were prompt in the IGDM and delayed in the normal newborns; corresponding values at 30 minutes were 30 ± 6 µU/ml in the IGDM and 15 ± 3 µU/ml in the normals.

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