Calcium-dependent protein kinase-C activity in human adrenocortical neoplasms, hyperplastic adrenals, and normal adrenocortical tissue.

1994 ◽  
Vol 79 (3) ◽  
pp. 736-739
Author(s):  
A C Latronico ◽  
B B Mendonça ◽  
A C Bianco ◽  
S M Villares ◽  
M A Lucon ◽  
...  
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Dependent Protein Kinase ◽  
Calcium Dependent ◽  
Kinase C ◽  
Protein Kinase C Activity ◽  
Dependent Protein ◽  
Calcium Dependent Protein Kinase

Calcium-dependent Protein Kinase Reactions Associated with Parotid Gland Secretory Granule Membranes

1987 ◽  
Vol 66 (2) ◽  
pp. 557-563 ◽  
Author(s):  
F. Dowd ◽  
E.L. Watson ◽  
Y.-S. Lau ◽  
J. Justin ◽  
J. Pasieniuk ◽  
...  
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Secretory Granule ◽  
Dependent Protein Kinase ◽  
Calcium Dependent ◽  
Kinase C ◽  
Protein Kinase C Activity ◽  
Granule Membrane ◽  
Dependent Protein ◽  
Calcium Dependent Protein Kinase

Rat parotid secretory granule membranes were examined for the presence of calcium-dependent protein kinase activities and kinase substrates. Protein kinase C (C-kinase), which is stimulated by certain phospholipids, was present in the membranes, as indicated by its ability to catalyze the phosphorylation of histone. Two substrates for protein kinase C were seen in the granule membranes. The cytosolic fraction from the cell contained kinase activity, which was stimulated by phosphatidylserine and which caused the phosphorylation of two granule membrane polypeptides. In addition, when both granule membranes and cytosol were incubated together, phosphorylation of the cytosolic substrates was inhibited, indicating that the granule membrane substrates were phosphorylated preferentially. The results indicate that the granule membranes may react with cytosolic protein kinase C activity in a way which would direct an intracellular calcium and diacylglycerol signal toward the granule membrane. Since these signals occur during stimulation by various agonists, the mechanism may contribute to secretion.

scholarly journals Calcium-Dependent Protein Kinase C Is Not Required for Post-Tetanic Potentiation at the Hippocampal CA3 to CA1 Synapse

2016 ◽  
Vol 36 (24) ◽  
pp. 6393-6402 ◽  
Author(s):  
Chih-Chieh Wang ◽  
Christopher Weyrer ◽  
Mounica Paturu ◽  
Diasynou Fioravante ◽  
Wade G. Regehr
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Dependent Protein Kinase ◽  
Calcium Dependent ◽  
Kinase C ◽  
Hippocampal Ca3 ◽  
Dependent Protein ◽  
Post Tetanic Potentiation ◽  
Calcium Dependent Protein Kinase

Phospholipid/calcium-dependent protein kinase (protein kinase C) system: A major site of bioregulation

1986 ◽  
Vol 25 ◽  
pp. 387-392 ◽  
Author(s):  
J.F. Kuo ◽  
Mamoru Shoji ◽  
Peggy R. Girard ◽  
Gonzalo J. Mazzei ◽  
R. Scott Turner ◽  
...  
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Major Site ◽  
Dependent Protein Kinase ◽  
Calcium Dependent ◽  
System A ◽  
Kinase C ◽  
Dependent Protein ◽  
Calcium Dependent Protein Kinase
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