scholarly journals Genetic Fusion of an α-Subunit Gene to the Follicle-Stimulating Hormone and Chorionic Gonadotropin-β Subunit Genes: Production of a Bifunctional Protein

1999 ◽  
Vol 13 (11) ◽  
pp. 1873-1881 ◽  
Author(s):  
Masatoshi Kanda ◽  
Albina Jablonka-Shariff ◽  
Asomi Sato ◽  
Mary R. Pixley ◽  
Ebo Bos ◽  
...  
Keyword(s):  
Chorionic Gonadotropin ◽  
Follicle Stimulating Hormone ◽  
Β Subunit ◽  
Subunit Gene ◽  
Α Subunit ◽  
Bifunctional Protein ◽  
Genetic Fusion ◽  
Stimulating Hormone

hCG production and activity during pregnancy

2001 ◽  
Vol 12 (3) ◽  
pp. 191-208 ◽  
Author(s):  
H S Randeva ◽  
A Jackson ◽  
E Karteris ◽  
E W Hillhouse
Keyword(s):  
Luteinizing Hormone ◽  
Chorionic Gonadotropin ◽  
Essential Role ◽  
Follicle Stimulating Hormone ◽  
Thyroid Stimulating Hormone ◽  
Β Subunit ◽  
Glycoprotein Hormone ◽  
Α Subunit ◽  
Hormone Specificity ◽  
Stimulating Hormone

Human chorionic gonadotropin (hCG) has an essential role in early pregnancy. It is a member of the glycoprotein hormone family also comprising the pituitary derived follicle stimulating hormone (FSH), luteinizing hormone (LH) and thyroid stimulating hormone (TSH). Each hormone consists of a non-covalently bound α and β subunit. Within a species the α subunit is identical and hormone specificity is determined by the unique β subunit.

scholarly journals Human Follicle-Stimulating Hormone β-Subunit Gene Encodes Multiple Messenger Ribonucleic Acids

1988 ◽  
Vol 2 (9) ◽  
pp. 806-815 ◽  
Author(s):  
J. Larry Jameson ◽  
Carolyn B. Becker ◽  
Christine M. Lindell ◽  
Joel F. Habener
Keyword(s):  
Follicle Stimulating Hormone ◽  
Β Subunit ◽  
Subunit Gene ◽  
Ribonucleic Acids ◽  
Stimulating Hormone

scholarly journals Activin Regulation of the Follicle-Stimulating Hormone β-Subunit Gene Involves Smads and the TALE Homeodomain Proteins Pbx1 and Prep1

2004 ◽  
Vol 18 (5) ◽  
pp. 1158-1170 ◽  
Author(s):  
Janice S. Bailey ◽  
Naama Rave-Harel ◽  
Shauna M. McGillivray ◽  
Djurdjica Coss ◽  
Pamela L. Mellon
Keyword(s):  
Follicle Stimulating Hormone ◽  
Β Subunit ◽  
Subunit Gene ◽  
Homeodomain Proteins ◽  
Tale Homeodomain ◽  
Stimulating Hormone

FSH in therapy: physiological basis, new preparations and clinical use

1995 ◽  
Vol 4 (3) ◽  
pp. 163-177 ◽  
Author(s):  
Manuela Simoni ◽  
Eberhard Nieschlag
Keyword(s):  
Follicle Stimulating Hormone ◽  
Thyroid Stimulating Hormone ◽  
Clinical Use ◽  
Β Subunit ◽  
Glycoprotein Hormone ◽  
Physiological Basis ◽  
Α Subunit ◽  
And Function ◽  
Polypeptide Chains ◽  
Stimulating Hormone

Follicle stimulating hormone (FSH) is a glycoprotein hormone secreted by the pituitary gland that, together with luteinizing hormone (LH), controls development, maturation and function of the gonad. Like the related hormones, LH, thyroid stimulating hormone (TSH) and human chorionic gonadotropin (hCG), FSH consists of two polypeptide chains, α and β, bearing carbohydrate moietiesN-linked to asparagine (Asn) residues. The α subunit is common to all members of the glycoprotein hormone family, whereas the β subunit, although structurally very similar, differs in each hormone and confers specificity of action.

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