Intravenous Acetaminophen (Paracetamol): Comparable Analgesic Efficacy, but Better Local Safety than Its Prodrug, Propacetamol, for Postoperative Pain After Third Molar Surgery

2005 ◽  
Vol 101 (1) ◽  
pp. 90-96 ◽  
Author(s):  
Philip Lange Moller ◽  
Gitte Irene Juhl ◽  
Catherine Payen-Champenois ◽  
Lasse Ansgar Skoglund
Keyword(s):  
Postoperative Pain ◽  
Third Molar ◽  
Analgesic Efficacy ◽  
Third Molar Surgery ◽  
Intravenous Acetaminophen ◽  
Local Safety

scholarly journals Analgesic Efficacy of Tramadol and Butorphanol in Mandibular Third Molar Surgery: A Comparative Study

2012 ◽  
Vol 13 (3) ◽  
pp. 364-370 ◽  
Author(s):  
Syed Sirajul Hassan ◽  
Anees Ahmed ◽  
Manjunath Rai ◽  
TM Kalappa
Keyword(s):  
Postoperative Pain ◽  
Comparative Study ◽  
Third Molar ◽  
Analgesic Efficacy ◽  
Third Molar Surgery ◽  
Tramadol Hydrochloride ◽  
Mandibular Third Molar ◽  
Duration Of Surgery ◽  
The Mean ◽  
Mandibular Third Molar Surgery

ABSTRACT Background Butorphanol tartrate, a mixed synthetic agonistantagonist opioid analgesic has been used for management of postoperative pain in minor and major surgical procedures.14,20 Tramadol hydrochloride is a centrally acting opioid which is effectively used in postoperative pain in various minor and major surgeries. Materials and methods Twenty subjects selected randomly received butorphanol tartrate 1 mg intramuscular and 20 subjects received tramadol hydrochloride 50 mg intramuscular after the removal of mandibular third molars. Time of injection, amount of anesthetic injected, duration of surgery, adverse effects were recorded.21 Results The mean amount of LA administered in butorphanol group was 2.6450 ml and in tramadol group was 2.640 ml respectively, the mean duration for surgery was 56.75 and 53.5 minutes for butorphanol and tramadol groups respectively which was statistically not significant. Pain assessment was done with VAS which showed mean of 19.2 and 15.5 mm (p = 0.001) which was significant for butorphanol and tramadol respectively after 12 hours. The mean time for rescue medication requirement was 5.9 hours (for tramadol) and 8.4 hours (for butorphanol). Effective analgesic activity was seen by butorphanol 1 mg intramuscular then tramadol 50 mg. Conclusion Butorphanol 1 mg was more effective than tramadol 50 mg in respect to postoperative analgesia. How to cite this article Hassan SS, Ahmed A, Rai M, Kalappa TM. Analgesic Efficacy of Tramadol and Butorphanol in Mandibular Third Molar Surgery: A Comparative Study. J Contemp Dent Pract 2012;13(3):364-370.

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