Solitary Fibrous Tumor of the Spinal Cord: Case Report and Review of the Literature

Neurosurgery ◽  
2004 ◽  
Vol 55 (2) ◽  
pp. E433-E438 ◽  
Author(s):  
Mitsuhiro Kawamura ◽  
Kazutaka Izawa ◽  
Noboru Hosono ◽  
Hiroshi Hirano

Abstract OBJECTIVE AND IMPORTANCE: A solitary fibrous tumor (SFT) is a rare neoplasm of probable mesenchymal origin that was first reported in the pleura but can occur in different sites. Only six cases of SFT arising from the spinal cord have been reported. CLINICAL PRESENTATION: We report a case of primary SFT occurring in the thoracic spinal cord in a 64-year-old man with Brown-Séquard syndrome. Magnetic resonance imaging revealed an intradural mass at the level of T2–T3. INTERVENTION: Total T2–T3 laminectomies were performed. The tumor appeared to be adherent to the right lateral aspect of the cord but not attached to the meninges. On histological examination, the tumor exhibited spindle cell proliferation with abundant dense collagen but without a hemangiopericytomatous pattern. Immunohistochemically, the tumor cells were reactive with CD34 and vimentin only. CONCLUSION: We report a rare case of SFT occurring in the thoracic spinal cord. Histologically and immunohistochemically, we confirmed the diagnosis of SFT. Low signal intensity on T1- and T2-weighted images corresponded to the histological findings. When a spinal cord tumor exhibits a signal pattern similar to this, SFT should be included in the differential diagnosis. Because of the rarity of reports on this condition, the clinical manifestations and course of SFT of the spinal cord are unknown, and careful long-term follow-up is recommended.

2014 ◽  
Vol 28 (3) ◽  
pp. 282-286
Author(s):  
Osamu Kawakami ◽  
Keisuke Yamada ◽  
Masahiro Kojima ◽  
Keiko Matsubayashi ◽  
Yuichiro Tsuge ◽  
...  

2020 ◽  
Vol 28 (1) ◽  
pp. 230949901989609
Author(s):  
Kazuma Murata ◽  
Kenji Endo ◽  
Takato Aihara ◽  
Yuji Matsuoka ◽  
Hirosuke Nishimura ◽  
...  

Background: Malignant solitary fibrous tumor (MSFT) arising from the spinal cord is extremely rare and poorly understood mesenchymal neoplasms: only a few MSFT in the spinal canal has been described. We describe the clinical course of the patient with MSFT arising from the thoracic spinal cord. Case report: We describe the clinical course of the patient and the radiological and pathological findings of the tumor. The tumor had been resected by microscopic posterior approach and video-assisted thoracic surgery, but local recurrence was observed by MRI at 1-year follow-up period. No metastatic lesion was confirmed. Then, carbon ion radiotherapy (CIRT) was administered to the recurrent lesion. Local suppression has been observed for 40 months after irradiation. Conclusion: Dumbbell-shaped MSFT arising from thoracic spinal cord is a highly unusual presentation. CIRT might be effective for treatment of recurrent tumors.


2005 ◽  
Vol 45 (7) ◽  
pp. 371-374 ◽  
Author(s):  
Tomoyuki OGAWA ◽  
Eiji MORIYAMA ◽  
Hiroichi BECK ◽  
Hiroshi SONOBE

Cureus ◽  
2021 ◽  
Author(s):  
Zachary T Olmsted ◽  
Joanna Tabor ◽  
Omer Doron ◽  
Hossein Hosseini ◽  
Daniel Schneider ◽  
...  

2013 ◽  
Vol 20 (2) ◽  
pp. 317-319 ◽  
Author(s):  
Marina Brigui ◽  
Sorin Aldea ◽  
Michele Bernier ◽  
Saad Bennis ◽  
Etienne Mireau ◽  
...  

2007 ◽  
Vol 68 (4) ◽  
pp. 461-463 ◽  
Author(s):  
Cumhur Kilinçer ◽  
Levent Öztürk ◽  
M. Kemal Hamamcioglu ◽  
Emre Altunrende ◽  
Sebahattin Çobanoglu

1984 ◽  
Vol 61 (4) ◽  
pp. 761-766 ◽  
Author(s):  
Michael Salcman ◽  
Ernesto Botero ◽  
Krishna C. V. Rao ◽  
Richard D. Broadwell ◽  
Eric Scott

✓ The development of a transplantable model brain tumor in the neonatal dog, the adaptation of the tumor to tissue culture, and the successful growth of the tumor in adult mongrel dogs has been adapted to producing similar tumors in the thoracic spinal cord of the adult dog. Ten adult dogs, weighing 4 to 25.4 kg each, were subjected to formal laminectomy. The tumor cell suspension was injected by hand with a Hamilton syringe at two or three sites over a distance of 1 cm; each site received an injection volume to 0.02 to 0.05 cc of the cell suspension after the dura had been opened. Immediately after injection the field was copiously irrigated and the puncture area sealed with a single drop of ethyl cyanoacrylate. Tumor cells for injection were obtained by thawing ampules stored at −195°C in a mixture of 10% dimethyl sulfoxide and RPMI 1640 culture medium. Cells were resuspended in Hank's balanced salt solution and 15% fetal calf serum on ice. Solutions had 90% cell viability, and animals received a dose in the range of 3 to 13 × 106 cells. Eight animals developed tumors and became paraparetic on the 9th to 14th postinjection day. Metrizamide myelography in three animals revealed complete blocks; two animals underwent spinal computerized tomography (CT) and demonstrated syringohydromyelia. Histology revealed the tumors to be highly vascular primitive neoplasms that invaded the surrounding cord. This spinal cord tumor model is large enough to be operated on, studied by CT and myelography, and subjected to pharmacological, electrophysiological, and blood flow study.


2014 ◽  
Vol 38 (2) ◽  
pp. 273 ◽  
Author(s):  
Jung Eun Park ◽  
Myung Eun Chung ◽  
Dae Heon Song ◽  
Hyun Sook Choi

2012 ◽  
Vol 31 (02) ◽  
pp. 61-67
Author(s):  
Joelton Fonseca ◽  
José Carlos Lynch ◽  
Fabiana Policarpo ◽  
Celestino Esteves ◽  
Cleber Bomfim ◽  
...  

Abstract Objective: Of this study is identifying the clinical manifestations, discuss the etiology, and present the surgical treatment nuances and outcomes of patients with sub dural arachnoidal cysts (AC). Method: A retrospective study was carried out with 7 consecutives patients with spinal cord subdural AC, diagnosed, evaluated and operated at the Neurosurgical department of Servidores do Estado Hospital, from 1996 to 2010. The radiological studies, patient records, surgical descriptions and surgical videos, were reviewed, creating a database from which information was collected. The follow-up varied from 2 to 168 months (mean, 48 months). All cysts were histopathological verified. Results: Five AC were located on the thoracic spinal cord, one were located anterior in the cervical region, and one at the lumbar spinal level. The complete resection of the cyst was performed in 4 surgeries. Three patients had cysts located ventral to the cord, which precluded complete excision. The symptoms in four patients demonstrated major improvement. There was no operative death in this series, there was no major complications related to surgery. Conclusion: AC should be considered in the differential diagnosis of lesions causing myelopathy and/or a radicular pain syndrome. Microsurgical resection or generous fenestration in cysts effectively ameliorated patients’ symptomatology.


2014 ◽  
Vol 21 (6) ◽  
pp. 899-904 ◽  
Author(s):  
Beate Poblete ◽  
Christoph Konrad ◽  
Karl F. Kothbauer

Object The aim of this study was to provide evidence for the effect of intrathecal morphine application after spinal cord tumor resection. Methods Twenty patients participated in a prospective open proof-of-concept study. During dural closure, morphine (7 μg/kg) was injected into the subarachnoid space. All patients were monitored in an intensive care setting postoperatively. Pain, additional opioids given, and vital parameters were recorded. Results Six patients received a mean morphine dose of 365 μg between C-3 and C-7 and 14 patients received a mean dose of 436 μg between T-2 and T-12. In the cervical and thoracic groups, the mean Numeric Rating Scale score was highest upon intensive care unit admission (1.2 and 2.5, respectively) and declined at 12 hours (0.5 and 0.8, respectively). Minimal extra morphine was required. Minor side effects occurred without consequence. Conclusions Intrathecal morphine for postoperative analgesia after resection of cervical and thoracic spinal cord tumors is effective and safe. These preliminary results require confirmation by larger comparative studies and further clinical experience.


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