scholarly journals Direct lineage reprogramming via pioneer factors; a detour through developmental gene regulatory networks

Development ◽  
2016 ◽  
Vol 143 (15) ◽  
pp. 2696-2705 ◽  
Author(s):  
Samantha A. Morris
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Developmental Gene ◽  
Lineage Reprogramming ◽  
Pioneer Factors ◽  
Gene Regulatory

scholarly journals Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids

Development ◽  
2018 ◽  
Vol 145 (24) ◽  
pp. dev167288 ◽  
Author(s):  
Eric M. Erkenbrack ◽  
Eric H. Davidson ◽  
Isabelle S. Peter
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Regulatory State ◽  
Developmental Gene ◽  
Gene Regulatory

Modeling Evolution of Developmental Gene Regulatory Networks

2021 ◽  
pp. 1013-1029
Author(s):  
Renske M. A. Vroomans ◽  
Kirsten H. W. J. ten Tusscher
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Developmental Gene ◽  
Gene Regulatory

scholarly journals Hub genes with positive feedbacks function as master switches in developmental gene regulatory networks

2009 ◽  
Vol 25 (15) ◽  
pp. 1898-1904 ◽  
Author(s):  
Chang H. Seo ◽  
Jeong-Rae Kim ◽  
Man-Sun Kim ◽  
Kwang-Hyun Cho
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Developmental Gene ◽  
Hub Genes ◽  
Positive Feedbacks ◽  
Gene Regulatory

Developmental gene regulatory networks in the zebrafish embryo

2009 ◽  
Vol 1789 (4) ◽  
pp. 279-298 ◽  
Author(s):  
Tzu-Min Chan ◽  
William Longabaugh ◽  
Hamid Bolouri ◽  
Hua-Ling Chen ◽  
Wen-Fang Tseng ◽  
...  
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Zebrafish Embryo ◽  
Developmental Gene ◽  
Gene Regulatory

scholarly journals Properties of developmental gene regulatory networks

2008 ◽  
Vol 105 (51) ◽  
pp. 20063-20066 ◽  
Author(s):  
E. H. Davidson ◽  
M. S. Levine
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Developmental Gene ◽  
Gene Regulatory

scholarly journals Structure of developmental gene regulatory networks from the perspective of cell fate-determining genes

Transcription ◽  
2016 ◽  
Vol 7 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Mercedes Martín ◽  
María F. Organista ◽  
Jose F. de Celis
Keyword(s):  
Cell Fate ◽  
Gene Regulatory Networks ◽  
Regulatory Networks ◽  
Developmental Gene ◽  
Gene Regulatory

Using ascidian embryos to study the evolution of developmental gene regulatory networks

2005 ◽  
Vol 83 (1) ◽  
pp. 75-89 ◽  
Author(s):  
Angela C Cone ◽  
Robert W Zeller
Keyword(s):  
Gene Regulatory Networks ◽  
Regulatory Network ◽  
Regulatory Networks ◽  
Regulatory Mechanisms ◽  
Developmental Gene ◽  
Regulatory Architecture ◽  
Ascidian Embryos ◽  
Gene Regulatory ◽  
Mode Of Development ◽  
Ascidian Embryo

Ascidians are ideally positioned taxonomically at the base of the chordate tree to provide a point of comparison for developmental regulatory mechanisms that operate among protostomes, non-chordate deuterostomes, invertebrate chordates, and vertebrates. In this review, we propose a model for the gene regulatory network that gives rise to the ascidian notochord. The purpose of this model is not to clarify all of the interactions between molecules of this network, but to provide a working schematic of the regulatory architecture that leads to the specification of endoderm and the patterning of mesoderm in ascidian embryos. We describe a series of approaches, both computational and biological, that are currently being used, or are in development, for the study of ascidian embryo gene regulatory networks. It is our belief that the tools now available to ascidian biologists, in combination with a streamlined mode of development and small genome size, will allow for more rapid dissection of developmental gene regulatory networks than in more complex organisms such as vertebrates. It is our hope that the analysis of gene regulatory networks in ascidians can provide a basic template which will allow developmental biologists to superimpose the modifications and novelties that have arisen during deuterostome evolution.

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