Molecular Phenotyping of Thyroid Tumors Identifies a Marker Panel for Differentiated Thyroid Cancer Diagnosis

2008 ◽  
Vol 15 (10) ◽  
pp. 2811-2826 ◽  
Author(s):  
Sam M. Wiseman ◽  
Adrienne Melck ◽  
Hamid Masoudi ◽  
Fariba Ghaidi ◽  
Lynn Goldstein ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Diagnosis ◽  
Differentiated Thyroid Cancer ◽  
Thyroid Tumors ◽  
Marker Panel ◽  
Molecular Phenotyping

scholarly journals 2016 Russian clinical practice guidelines for differentiated thyroid cancer diagnosis and treatment

2017 ◽  
Vol 11 (1) ◽  
pp. 6-27 ◽  
Author(s):  
Dmitriy G. Beltsevich ◽  
Vladimir E. Vanushko ◽  
Pavel O. Rumiantsev ◽  
Galina A. Melnichenko ◽  
Nikolay S. Kuznetsov ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Clinical Practice ◽  
Cancer Diagnosis ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Differentiated Thyroid Cancer ◽  
Diagnosis And Treatment

В представленных клинических рекомендациях обсуждаются современные подходы к диагностике и лечению дифференцированного рака щитовидной железы у взрослых. Изменения в настоящей редакции Клинических рекомендаций касаются показаний к пункционной биопсии, скринингового определения концентрации кальцитонина, унификации заключений цитологического исследования, новых подходах к послеоперационной динамической стратификации риска рецидива, показаний к супрессивной и заместительной терапии, таргетной терапии йоднегативных форм дифференцированного рака щитовидной железы.

scholarly journals PPARγPromotes Growth and Invasion of Thyroid Cancer Cells

PPAR Research ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
William M. Wood ◽  
Vibha Sharma ◽  
Kevin T. Bauerle ◽  
Laura A. Pike ◽  
Qiong Zhou ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Cyclin A ◽  
Anaplastic Thyroid Cancer ◽  
Thyroid Tumors ◽  
Cycle Arrest ◽  
Invasive Capacity ◽  
Advanced Thyroid Cancer ◽  
Thyroid Cancer Cells

Undifferentiated (anaplastic) thyroid cancer (ATC) is one of the most aggressive human malignancies and no effective therapy is currently available. We show here that PPARγlevels are elevated in cells derived from ATC. Depletion of PPARγin HTh74 ATC cells resulted in decreased cell growth, cell cycle arrest and a reduction in pRb and cyclin A and B1 levels. We further showed that both flank and orthotopic thyroid tumors derived from PPARγ-depleted cells grew more slowly than PPARγ-expressing cells. When PPARγwas overexpressed in more differentiated thyroid cancer BCPAP cells which lack PPARγ, there was increased growth and raised pRb and cyclin A and B1 levels. Finally, PPARγdepletion in ATC cells decreased their invasive capacity whereas overexpression in PTC cells increased invasiveness. These data suggest that PPARγmay play a detrimental role in thyroid cancer and that targeting it therapeutically may lead to improved treatment of advanced thyroid cancer.

scholarly journals Circulating Myeloid-Derived Suppressor Cells Predict Differentiated Thyroid Cancer Diagnosis and Extent

Thyroid ◽  
2016 ◽  
Vol 26 (3) ◽  
pp. 381-389 ◽  
Author(s):  
Trevor E. Angell ◽  
Melissa G. Lechner ◽  
Alison M. Smith ◽  
Sue E. Martin ◽  
Susan G. Groshen ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Diagnosis ◽  
Differentiated Thyroid Cancer ◽  
Suppressor Cells ◽  
Myeloid Derived Suppressor Cells

scholarly journals ANGPTL1 is a potential biomarker for differentiated thyroid cancer diagnosis and recurrence

2020 ◽  
Vol 20 (5) ◽  
pp. 1-1
Author(s):  
Rongxin Sun ◽  
Longyan Yang ◽  
Yangping Hu ◽  
Yan Wang ◽  
Qiang  Zhang ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Diagnosis ◽  
Differentiated Thyroid Cancer ◽  
Potential Biomarker

scholarly journals Nuclear medicine impact on differentiated thyroid cancer diagnosis and treatment

2019 ◽  
Vol 154 (4) ◽  
Author(s):  
Sevastián Medina-Ornelas ◽  
Francisco García-Pérez ◽  
Martín Granados-García
Keyword(s):  
Nuclear Medicine ◽  
Thyroid Cancer ◽  
Cancer Diagnosis ◽  
Differentiated Thyroid Cancer ◽  
Diagnosis And Treatment
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