Background:
Phytoconstituents of fruits, vegetables, spice and herbs are important for human
health. Phytoconstituents play an important role in the growth, development, defensive mechanism,
colors, odour and flavors of plants. Psoralea corylifolia Linn (P. corylifolia) commonly known as ‘Bakuchi’
belongs to Leguminosae family widely distributed in China and Southeastern Asian countries.
Methods:
Various electronic databases such as PubMed, Science Direct, Scopus and Google were
searched to collect the data of the present review. Further, all the collected information was categorized
into different section as per the aim of the paper. Moreover, analyzed data were also presented in the
graphical abstract.
Results:
Seventy-two research and review papers have been collected and were included in the present
review. Nineteen papers contained general information’s of P. corylifolia, Psoralens and psoralidin
whereas thirty paper data were presented in the pharmacological activities sections and remaining in the
Analytical tools and discussion section. From these databases, we can say that P. corylifolia possesses
antibacterial, anti-inflammatory, antifungal, antioxidant, antiflarial, estrogenic, antitumour, and immunomodulatory
activities. Psoralens are mainly used in the treatment of psoriasis, vitiligo and dermatitis.
Topical or oral psoralens followed by UVA radiation exposure are one of the best treatments of leucoderma.
Psoralidin exhibits antioxidant, anti-apoptotic, anti-inflammatory and antitumor activities.
Conclusion:
This review summarizes an overview of P. corylifolia, psoralen and its derivative
psoralidin with respects to their pharmacological activities, medicinal uses, biological activities and
bioanalytical aspects. These data will be helpful in the translation of information from traditional to the
modern medicine of psoralidin.
Triterpenoid Saponins from the Seeds of Celosia argentea and Their Anti-inflammatory and Antitumor Activities
