scholarly journals A Simple Method for Quantitative Determination of Active Drug Polymorphs and Amorphous in Drug Products by Fourier Transform-Raman Spectroscopy

2005 ◽  
Vol 125 (10) ◽  
pp. 807-814 ◽  
Author(s):  
Takahiro UENO ◽  
Koji URAKAMI ◽  
Atsuya HIGASHI ◽  
Kazuichi UMEMOTO ◽  
Masayuki GODO ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Quantitative Determination ◽  
Active Drug ◽  
Simple Method ◽  
Drug Products ◽  
Fourier Transform Raman Spectroscopy ◽  
Fourier Transform Raman

Determination of Methamphetamine and its Related Compounds Using Fourier Transform Raman Spectroscopy

1997 ◽  
Vol 51 (12) ◽  
pp. 1796-1799 ◽  
Author(s):  
Hitoshi Tsuchihashi ◽  
Munehiro Katagi ◽  
Mayumi Nishikawa ◽  
Michiaki Tatsuno ◽  
Hiroshi Nishioka ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Ephedrine Hydrochloride ◽  
Fourier Transform Raman Spectroscopy ◽  
Plastic Bag ◽  
Amphetamine Sulfate ◽  
Fourier Transform Raman ◽  
Related Compounds ◽  
Ft Raman

Fourier transform Raman spectroscopy (FT-Raman) is investigated as a simple and rapid method for the determination of the abused drug methamphetamine and its related compounds. Compounds can be reliably identified by using measurements made nondestructively and without the need for any sample preparation in around 1 min. The Raman spectrum of methamphetamine hydrochloride (MA) shows clear differences in spectra from a range of its related compounds such as amphetamine sulfate and ephedrine hydrochloride. These differences are adequate for spectral differentiation of the compounds. With the use of the FT-Raman technique, MA is also reliably identifiable to a detection limit of 1% (w/w) diluted in sodium chloride or water. FT-Raman spectra of MA were recorded through plastic packaging (polyethylene or polypropylene bags) typical of that used either by criminals for transportation or by law enforcement for containing and sealing evidence. Measurements could be made directly without removing the drug from the bag; excellent-quality spectra could be obtained with very little perturbation by the plastic bag.

Determination of the Conjugated Linoleic Acids in Cow's Milk Fat by Fourier Transform Raman Spectroscopy

2005 ◽  
Vol 53 (15) ◽  
pp. 5831-5835 ◽  
Author(s):  
Marc Meurens ◽  
Vincent Baeten ◽  
Shou He Yan ◽  
Eric Mignolet ◽  
Yvan Larondelle
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Milk Fat ◽  
Cow’S Milk ◽  
Conjugated Linoleic Acids ◽  
Cow's Milk ◽  
Fourier Transform Raman Spectroscopy ◽  
Fourier Transform Raman
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