scholarly journals KCNA4 Gene Variant is Auxiliary in the Complex Phenotype of Endurance Running Performance Level

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 576
Author(s):  
Keven Flecha-Velazquez ◽  
Thomas D. Fahey ◽  
Juan L. Martinez-Barreda ◽  
Juan R. Lopez-Taylor ◽  
Miguel A. Rivera
Keyword(s):  
Performance Level ◽  
Gene Variant ◽  
Endurance Running ◽  
Complex Phenotype ◽  
Running Performance ◽  
Endurance Running Performance

KCNA4 Gene Variant is Auxiliary in Endurance Running Performance Level

2019 ◽  
Vol 40 (05) ◽  
pp. 354-358
Author(s):  
Keven Flecha-Velazquez ◽  
Thomas Fahey ◽  
Juan Martínez ◽  
Juan Lopez-Taylor ◽  
Miguel Rivera
Keyword(s):  
Statistical Power ◽  
Endurance Performance ◽  
Performance Level ◽  
Endurance Running ◽  
Marathon Runners ◽  
Running Performance ◽  
Genotype Frequencies ◽  
Gated Channel ◽  
Endurance Running Performance ◽  
Hispanic Male

AbstractThe present is an observational study following a genetic epidemiology model using a case-control design. We tested the hypothesis of an association between the prevalence of the genotypic and allelic frequencies distribution of the potassium voltage-gated channel of the shaker related subfamily member 4 gene (KCNA4) rs1323860 (C/T transition) and endurance performance level in Hispanic male marathon runners (MR). The subjects (n=1876) were adult Hispanic male MR. Fast-MR (cases; n=938) were finishers in the top 3rd percentile. Slow MR (controls; n=938) were finishers in the lowest 3rd percentile of their respective age. Genomic DNA was purified from a whole blood sample. Polymerase chain reaction was used to amplify a KCNA4 SNP which consists of a C/T (rs1323860) transition. The observed genotype frequencies, in both Cases and Controls, met Hardy-Weinberg equilibrium (X2, P≥0.05). Genotype and allele frequencies were statistically different (P<0.01) between cases and controls. Odds ratio revealed that the C allele was 1.33 times more likely prevalent in the cases than in the controls (95% CI; 1.17, 1.51; P<0.001). The magnitude of the statistical power for the present study was 0.86. In conclusion, the findings strongly suggest that KCNA4 gene rs1323860 (C/T transition) is auxiliary in the complex phenotype of endurance running performance level in Hispanic male marathon runners.

Acute effect of dynamic stretching or running on endurance running performance in well-trained male runners

2020 ◽  
Vol 179 (1-2) ◽  
Author(s):  
Taichi Yamaguchi ◽  
Kazuki Takizawa ◽  
Keisuke Shibata ◽  
Nobuyasu Tomabechi ◽  
Mina Samukawa ◽  
...  
Keyword(s):  
Acute Effect ◽  
Endurance Running ◽  
Running Performance ◽  
Dynamic Stretching ◽  
Endurance Running Performance

The key to top-level endurance running performance: a unique example

2008 ◽  
Vol 42 (3) ◽  
pp. 172-174 ◽  
Author(s):  
A. Lucia ◽  
J. Olivan ◽  
J. Bravo ◽  
M. Gonzalez-Freire ◽  
C. Foster
Keyword(s):  
Endurance Running ◽  
Running Performance ◽  
Endurance Running Performance

scholarly journals Age-related decline in endurance running performance – an example of a multiple World records holder

2018 ◽  
Vol 43 (1) ◽  
pp. 98-100 ◽  
Author(s):  
Romuald Lepers ◽  
Thomas Cattagni
Keyword(s):  
Advanced Age ◽  
Endurance Running ◽  
Running Performance ◽  
Age Related ◽  
Endurance Running Performance ◽  
Rate Of Decline ◽  
World Records

This study examined the age-related decline in endurance running performance of one of the greatest master runners ever, Ed Whitlock, who died recently. His running performances from 1500 m to marathon were analyzed for 5 periods of 5 years from 65–69 years to 85–89 years. Despite exceptional running performances for his advanced age, the rate of decline in his performances increased after 80 years and was drastically amplified after 85 years.

Influence of fluid intake on endurance running performance

1990 ◽  
Vol 60 (2) ◽  
pp. 112-119 ◽  
Author(s):  
C. Williams ◽  
M. G. Nute ◽  
L. Broadbank ◽  
S. Vinall
Keyword(s):  
Fluid Intake ◽  
Endurance Running ◽  
Running Performance ◽  
Endurance Running Performance

The validity of endurance running performance on the Curve 3TMnon-motorised treadmill

2014 ◽  
Vol 33 (11) ◽  
pp. 1141-1148 ◽  
Author(s):  
Christopher J. Stevens ◽  
Jake Hacene ◽  
Benjamin Wellham ◽  
Dean V. Sculley ◽  
Robin Callister ◽  
...  
Keyword(s):  
Endurance Running ◽  
Running Performance ◽  
Endurance Running Performance

The Effect Of Dairy Calcium Intake On Fat Metabolism During Exercise And Endurance Running Performance

2005 ◽  
Vol 37 (Supplement) ◽  
pp. S142
Author(s):  
Kimberly White ◽  
Roseann M. Lyle ◽  
Michael G. Flynn ◽  
Dorothy Teegarden ◽  
Shawn S. Donkin
Keyword(s):  
Calcium Intake ◽  
Fat Metabolism ◽  
Endurance Running ◽  
Running Performance ◽  
Endurance Running Performance

The Effects of Wearing Undersized Lower-Body Compression Garments on Endurance Running Performance

2011 ◽  
Vol 6 (2) ◽  
pp. 160-173 ◽  
Author(s):  
Ben J. Dascombe ◽  
Trent K. Hoare ◽  
Joshua A. Sear ◽  
Peter R. Reaburn ◽  
Aaron T. Scanlan
Keyword(s):  
Oxygenation Index ◽  
Running Economy ◽  
Time To Exhaustion ◽  
Lower Body ◽  
Endurance Running ◽  
Venous Flow ◽  
Compression Garments ◽  
Running Performance ◽  
Endurance Running Performance ◽  
Physiological Benefits

Purpose:To examine whether wearing various size lower-body compression garments improves physiological and performance parameters related to endurance running in well-trained athletes.Methods:Eleven well-trained middle-distance runners and triathletes (age: 28.4 ± 10.0 y; height: 177.3 ± 4.7 cm; body mass: 72.6 ± 8.0 kg; VO2max: 59.0 ± 6.7 mL·kg–1·min–1) completed repeat progressive maximal tests (PMT) and time-to-exhaustion (TTE) tests at 90% VO2max wearing either manufacturer-recommended LBCG (rLBCG), undersized LBCG (uLBCG), or loose running shorts (CONT). During all exercise testing, several systemic and peripheral physiological measures were taken.Results:The results indicated similar effects of wearing rLBCG and uLBCG compared with the control. Across the PMT, wearing either LBCG resulted in significantly (P < .05) increased oxygen consumption, O2 pulse, and deoxyhemoglobin (HHb) and decreased running economy, oxyhemoglobin, and tissue oxygenation index (TOI) at low-intensity speeds (8–10 km·h–1). At higher speeds (12–18 km·h-1), wearing LBCG increased regional blood fow (nTHI) and HHb values, but significantly lowered heart rate and TOI. During the TTE, wearing either LBCG significantly (P < .05) increased HHb concentration, whereas wearing uLBCG also significantly (P < .05) increased nTHI. No improvement in endurance running performance was observed in either compression condition.Conclusion:The results suggest that wearing LBCG facilitated a small number of cardiorespiratory and peripheral physiological benefits that appeared mostly related to improvements in venous flow. However, these improvements appear trivial to athletes, as they did not correspond to any improvement in endurance running performance.

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