scholarly journals Fluid Shifts With Acute Exposure To Normobaric And Hypobaric Hypoxia

2021 ◽  
Vol 53 (8S) ◽  
pp. 353-353
Author(s):  
Larry Robins ◽  
Brent Ruby ◽  
Walter Hailes ◽  
Christopher Collins ◽  
Dustin Slivka
2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Larry Robins ◽  
Brent Ruby ◽  
Walter Hailes ◽  
Christopher Collins ◽  
Dustin Slivka

PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e114072 ◽  
Author(s):  
Belén Feriche ◽  
Amador García-Ramos ◽  
Carmen Calderón-Soto ◽  
Franchek Drobnic ◽  
Juan G. Bonitch- Góngora ◽  
...  

2003 ◽  
Author(s):  
Allen Cymerman ◽  
Steven R. Muza ◽  
Dan Ditzler ◽  
Mark Sharp ◽  
Anne Friedlander

2020 ◽  
Vol 91 (11) ◽  
pp. 845-851
Author(s):  
Mathias Roland Aebi ◽  
Nicolas Bourdillon ◽  
Philip Noser ◽  
Grgoire Paul Millet ◽  
Denis Bron

INTRODUCTION: Exposure to hypoxia has a deleterious effect on cognitive function; however, the putative effect of hypobaria remains unclear. The present study aimed to evaluate cognitive performance in pilot trainees who were exposed to acute normobaric (NH) and hypobaric hypoxia (HH). Of relevance for military pilots, we also aimed to assess cognitive performance in hypobaric normoxia (HN).METHODS: A total of 16 healthy pilot trainees were exposed to 4 randomized conditions (i.e., normobaric normoxia, NN, altitude level of 440 m; HH at 5500 m; NH, altitude simulation of 5500 m; and HN). Subjects performed a cognitive assessment (KLT-R test). Cerebral oxygen delivery (cDO2) was estimated based middle cerebral artery blood flow velocity (MCAv) and pulse oxygen saturation (Spo2) monitored during cognitive assessment.RESULTS: Percentage of errors increased in NH (14.3 9.1%) and HH (12.9 6.4%) when compared to NN (6.5 4.1%) and HN (6.0 4.0%). Number of calculations accomplished was lower only in HH than in NN and HN. When compared to NN, cDO2 decreased in NH and HH.DISCUSSION: Cognitive performance was decreased similarly in acute NH and HH. The cDO2 reduction in NH and HH implies insufficient MCAv increase to ensure cognitive performance maintenance. The present study suggests negligible hypobaric influence on cognitive performance in hypoxia and normoxia.Aebi MR, Bourdillon N, Noser P, Millet GP, Bron D. Cognitive impairment during combined normobaric vs. hypobaric and normoxic vs. hypoxic acute exposure. Aerosp Med Hum Perform. 2020; 91(11):845851.


Nitric Oxide ◽  
2017 ◽  
Vol 69 ◽  
pp. 1-9 ◽  
Author(s):  
Heath G. Gasier ◽  
Anthony R. Reinhold ◽  
Allison R. Loiselle ◽  
Shawn E. Soutiere ◽  
David M. Fothergill

2004 ◽  
Vol 97 (2) ◽  
pp. 599-604 ◽  
Author(s):  
Misa Yoshimoto ◽  
Mitsuko Sasaki ◽  
Nobuo Naraki ◽  
Motohiko Mohri ◽  
Kenju Miki

The aim of the present study was to examine the effects of acute exposure to hypobaric hypoxia on gastric and colonic motilities. Wistar rats, which were instrumented chronically with strain gauge force transducer to measure gastric and colonic motilities, were exposed acutely to hypobaric hypoxia [0.5 atmosphere absolute (ATA, 380 Torr)] over 1 h. In a separate group, the gastric branches of the vagal nerves were cut and underwent the same experimental protocol. Each contraction wave of the stomach and colon was analyzed into frequency and area under the curves, which were then averaged every 10 min. Acute exposure to 0.5 ATA resulted in significant ( P < 0.05) decreases in frequency and area of gastric contraction wave by 0.5 ± 0.1 cycles/min and 64.6 ± 4.0%, respectively. Gastric vagotomy abolished completely the suppression in the area observed in the intact rats during the 0.5-ATA exposures. Colonic motility increased significantly only at the start and end of exposure to 0.5 ATA and sham exposure [1 ATA (760 Torr), time control] in both intact and vagotomized rats. These data suggest that the acute suppression of the area of the gastric contraction wave that occurred during 0.5-ATA exposure is likely to be mediated by the vagal nerve.


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