Extraskeletal Ewing’s sarcoma of the nose

A 20-year-old woman presented with nasal obstruction and slight epistaxis. The obstructing lesion was excised and microscopy showed a neoplasm composed of comparatively uniform undifferentiated cells forming solid nests. The cytoplasm of the cells was clear but poorly demarcated, partly vacuolated and contained much glycogen. Although widespread in the nasal mucosa, the cells did not penetrate into the underlying bone.The cells expressed the MIC2 gene (using the CD99 marker). Electron microscopy showed simple cells with a small number of mitochondria, many glycogen particles; there were no neurosecretory granules present.Early surgical treatment followed by chemo- and radiotherapy have greatly improved the prognosis of EWS: extraskeletal Ewing’s sarcoma (EWS/PNET).

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Extraskeletal Ewing's Sarcoma Occurring as a Mass in the Neck

Otolaryngology ◽

10.1177/019459988209000422 ◽

1982 ◽

Vol 90 (4) ◽

pp. 491-493 ◽

Cited By ~ 9

Author(s):

Ray O. Gustafson ◽

Nicolas E. Maragos ◽

Herbert M. Reiman

Keyword(s):

Young Adults ◽

Radiation Therapy ◽

Stem Cell ◽

Surgical Treatment ◽

Mesenchymal Stem Cell ◽

Ewing’S Sarcoma ◽

Ewing's Sarcoma ◽

Malignant Neoplasm ◽

Aggressive Therapy ◽

Extraskeletal Ewing’S Sarcoma

Extraskeletal Ewing's sarcoma is a rare malignant neoplasm. Arising from a primitive mesenchymal stem cell and primarily affecting young adults, this lesion demands aggressive therapy, including surgical treatment, radiation therapy, and chemotherapy.

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Extraskeletal Ewing’s sarcoma presenting as a neck mass - case report

ORL ro ◽

10.26416/orl.35.2.2017.795 ◽

2017 ◽

Vol 2 (35) ◽

pp. 24

Author(s):

Daniel Mirea ◽

Loredana Mitran ◽

Daniela Safta ◽

Cornelia Niţipir ◽

Bogdan Mocanu ◽

...

Keyword(s):

Case Report ◽

Ewing’S Sarcoma ◽

Ewing's Sarcoma ◽

Neck Mass ◽

Extraskeletal Ewing’S Sarcoma ◽

Mass Case

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Reconstruction after Subtotal Sacrectomy for Sacral Ewing’s Sarcoma Using Tibial Allograft Strut Grafting: A Case Report

Case Reports in Oncology ◽

10.1159/000513117 ◽

2021 ◽

pp. 296-302

Author(s):

Ryosuke Hirota ◽

Makoto Emori ◽

Yoshinori Terashima ◽

Kousuke Iba ◽

Noriyuki Iesato ◽

...

Keyword(s):

Surgical Treatment ◽

Ewing’S Sarcoma ◽

Mechanical Stability ◽

Ewing's Sarcoma ◽

Lumbar Vertebrae ◽

Iliac Screws ◽

Sacral Tumor ◽

Sacral Resection ◽

High Mechanical Stability ◽

Rectal Dysfunction

We present the case of a 15-year-old girl. Two months after becoming aware of pain, she was diagnosed with a sacral tumor and referred to our department. She was diagnosed with a sacral Ewing’s sarcoma; after chemotherapy, it was determined that the tumor could be resected, so surgical treatment was performed. The sacrum and ilium were partially resected at the lower end of S1, and the lumbar vertebrae and pelvis were fixed with a pedicle screw and two iliac screws on each side of L3, and the sacral resection was reconstructed with a tibial strut allograft. No tumor recurrence or metastasis has been observed 1 year postoperatively. She developed bladder and rectal dysfunction, but she remained independent in activities of daily living and her daily life was not limited. The bone fusion in the reconstructed area confirmed the lack of instrumentation looseness. Surgical treatment for sacral Ewing’s sarcoma was performed to cure the patient. We believe that the tibial allograft contributed to the patient’s ability to walk on her own due to its high mechanical stability. Postoperative bone healing was observed with the same material, suggesting that the tibial allograft is useful for similar procedures.

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