Monitoring of blood gas parameters and acid-base balance of pregnant and non-pregnant rabbits (Oryctolagus cuniculus) in routine experimental conditions

1992 ◽  
Vol 26 (2) ◽  
pp. 73-79 ◽  
Author(s):  
M. M. Barzago ◽  
A. Bortolotti ◽  
D. Omarini ◽  
J. J. Aramayona ◽  
M. Bonati
Keyword(s):  
New Zealand ◽  
Oryctolagus Cuniculus ◽  
Housing Conditions ◽  
Blood Gas ◽  
Acid Base Balance ◽  
Acid Base ◽  
Experimental Conditions ◽  
Physiological Conditions ◽  
Base Balance ◽  
Blood Gas Parameters

Blood gas parameters and acid-base balance values were determined in adult pregnant New Zealand rabbits ( Oryctolagus cuniculus) in standard laboratory housing conditions and during anaesthesia with an association of ketamine-chlorpromazine, administered before surgical procedures. All the variables were also studied in adult non-pregnant female, used as controls. No differences in pH, sO2c, O2Hb, COHb, sO2m and a-vDO2 were found between pregnant and non-pregnant rabbits in physiological conditions and during anaesthesia. Ketamine-chlorpromazine and pregnancy seemed to change the other parameters used to assess the acid-base balance and the oxygenation conditions. Anaesthesia affected only Hb, O2Ct, O2Cap, CcO2 and P50. The additive effect of pregnancy and anaesthesia modified pCO2, pO2, HCO3-, TCO2, BEb, SBC, BEecf, A-aDO2, RI, MetHb, RHb, CaO2 and CvO2. The patterns described are close to those of other species, suggesting the New Zealand rabbit might be a reliable animal model for monitoring selected variables.

scholarly journals Features of gas composition and acid-base state of blood in newborns with intrauterine infections

2021 ◽  
pp. 59-65
Author(s):  
K. I. Ismoilov ◽  
Sh. S. Muzaffarov
Keyword(s):  
Blood Gases ◽  
Gas Composition ◽  
Blood Gas ◽  
Acid Base Balance ◽  
Acid Base ◽  
Hyperventilation Syndrome ◽  
Base Balance ◽  
Blood Gas Parameters ◽  
Buffer States ◽  
Intrauterine Infections

Aim. To study the features of the gas composition and acid-base state in newborns with specific intrauterine infections.Material and methods. The examination was conducted based on the neonatal pathology unit of the SI NMCShifobakhsh.The degree of oxygenation of blood and skin was determined using daily pulse-oximetry. The partial pressure of gases and the study of the acid-base state (CBS) of blood was carried out using Convergys/liquid device.Result and discussion. The results of our study of blood gases and the acid-base indicator of blood in newborns with severe IUI showed noticeable hypoxemia, moderate hypercapnia, and a deficiency of buffer States, which indicate a violation of gas exchange function in the lungs with the development of compensatory respiratory-metabolic acidosis in children of this group. In patients with a very severe course of IUI, as the syndrome of respiratory disorders and the severity of hyperventilation syndrome increased, deeper changes in blood gas parameters and the acid-base state of the blood were noted. It indicates significant damage to the ventilation function of the lungs, diffuse perfusion processes, gas, and acid-base homeostasis.Conclusions. Impairment of the function of organs and systems that developed against the background of a severe or very severe course of IUI, depending on the degree of severity of deviations in blood gas parameters and acid-base balance, shows the need for adequate corrective therapy.

Acid-Base Balance and Blood Gas Interpretation

2001 ◽  
pp. 131-146
Author(s):  
M. Fareed Azam ◽  
William T. Peruzzi
Keyword(s):  
Blood Gas ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

Acid-Base Balance and Blood Gas Analysis

2018 ◽  
pp. 495-526
Author(s):  
Felice Eugenio Agrò ◽  
Marialuisa Vennari ◽  
Maria Benedetto
Keyword(s):  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

scholarly journals Association between Acid-Base Balance and Asphyxia in Newborn Infants

2018 ◽  
Vol 34 (1-2) ◽  
pp. 38-43
Author(s):  
Sari Leyli Harahap ◽  
Chairul Adillah Harahap ◽  
Sri Sulastri ◽  
Chairul Yoel ◽  
Noersida Raid
Keyword(s):  
Apgar Score ◽  
Newborn Infants ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Acid Base Balance ◽  
Acid Base ◽  
Apgar Scores ◽  
Arterial Blood ◽  
Base Balance

We performed a prospective study on the association between acid-base balance and asphyxta based on Apgar scores in 45 newborn babies admitted to the Division of Perinatology, Pirngadi Hospital, Medan, from January 1 to February 28, 1993. Blood gas analysis was done on blood obtained from umbilical artery. Based on 1st and 5th minutes Apgar scores, 40 (88.9%) and 21 babies (46.7%}, respectively, had asphyxia. Relation to acid-base balance was determined with the sensitivity of the 5th minute Apgar score in predicting acidotic states. It was found that Apgar score had sensitivity of 57.7% and specificity of 68.4% in predicting the acidotic states. Apgar score of > 7 was unable to. exclude the possible acidosis in 45% of cases (negative predictive value 54.1%). Gestational age had no influence on Apgar Scores. Apgar score was more sensitive to eliminate suspected acidosis in term neonates than in preterms. We recommend to perform umbilical arterial blood gas analysis to determine acidotic state in high risk newborn infants.

Blood Gas Analysis and the Fundamentals of Acid-Base Balance

2009 ◽  
Vol 28 (2) ◽  
pp. 125-128 ◽  
Author(s):  
Mary Farmand
Keyword(s):  
Systematic Approach ◽  
Blood Gases ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Acid Base Balance ◽  
Bedside Nurse ◽  
Acid Base ◽  
Neonatal Nursing ◽  
Base Balance

UNDERSTANDING BLOOD GAS values and acid-base balance are fundamental skills of neonatal nursing. This is because, in the NICU, blood gases are probably ordered more than any other laboratory test. The bedside nurse not only obtains the specimen, but is also crucially involved in interpreting the results because blood gases cannot stand alone; they need to be evaluated in the context of the entire clinical picture. This article provides basic information on the components of a blood gas, acid-base balance, as well as a systematic approach to blood gas analysis.

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