Demonstration of Epstein-Barr virus DNA and human papillomavirus DNA in acetowhite lesions of the penile skin and the oral mucosa

1997 ◽  
Vol 8 (12) ◽  
pp. 772-775 ◽  
Author(s):  
Ewa Voog ◽  
Anne Ricksten ◽  
Sigvard Olofsson ◽  
Annika Ternesten ◽  
Walter Ryd ◽  
...  

Summary: Oral hairy leukoplakia (OHL), thought to be caused by Epstein-Barr virus (EBV), shows similar histological and clinical features to human papillomavirus (HPV)-related acetowhite lesions of the vulva. We thus aimed to investigate the role of both HPV and EBV in men with acetowhite lesions of the penis. HPV but not EBV was significantly associated with penile acetowhite lesions showing koilocytosis compared with normal penile skin (12/20 versus 5/20, P 0.02). HPV (5/20) and EBV (6/20) was detected in oral mucosa of some of these individuals. These results confirm an aetiological association between HPV and acetowhite penile lesions showing koilocytosis. HPV and EBV carriage in the oral mucosa is relatively common in young sexually active men. <

2004 ◽  
Vol 190 (2) ◽  
pp. 387-395 ◽  
Author(s):  
Dennis M. Walling ◽  
Wiguins Etienne ◽  
Autumn J. Ray ◽  
Catherine M. Flaitz ◽  
C. Mark Nichols

1994 ◽  
Vol 5 (1) ◽  
pp. 25-28 ◽  
Author(s):  
E Voog ◽  
A Ricksten ◽  
G B Löwhagen ◽  
A Ternesten

Acetowhite lesions in the vulva disclosing koilocytosis have been related to infection by human papilloma virus (HPV). Because of the clinical resemblance of these lesions to oral hairy leukoplakia (OHL), and EBV-manifestation, 23 women with acetowhite koilocytotic lesions in the vulva were examined. The PCR-technique was used to detect EBV DNA as well as HPV DNA in 17% of 23 patients examined. In a control group of 19 patients EBV DNA was detected in 11% and HPV DNA in 42% of cell samples from normal vulvar mucosa. EBV DNA has not previously been demonstrated in the vulvar mucosa, and this virus might be related to subclinical acetowhite lesions.


2015 ◽  
Vol 73 ◽  
pp. 70-76 ◽  
Author(s):  
Sirinart Aromseree ◽  
Chamsai Pientong ◽  
Piyawut Swangphon ◽  
Arkom Chaiwongkot ◽  
Natcha Patarapadungkit ◽  
...  

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