Advances in the Study of Blood Pressure Management in Acute Phase of Ischemic Stroke Patients

2021 ◽  
Vol 11 (01) ◽  
pp. 42-48
Author(s):  
介石 钟
Keyword(s):  
Blood Pressure ◽  
Ischemic Stroke ◽  
Acute Phase ◽  
Pressure Management ◽  
Stroke Patients ◽  
Blood Pressure Management

scholarly journals Emergency Department Adherence to American Heart Association Guidelines for Blood Pressure Management in Acute Ischemic Stroke

Stroke ◽  
2012 ◽  
Vol 43 (2) ◽  
pp. 557-559 ◽  
Author(s):  
Erin McDonough Grise ◽  
Opeolu Adeoye ◽  
Christopher Lindsell ◽  
Kathleen Alwell ◽  
Charles Moomaw ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Emergency Department ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
American Heart Association ◽  
American Heart ◽  
Heart Association ◽  
Pressure Management ◽  
Blood Pressure Management

Blood Pressure Management in Early Ischemic Stroke

JAMA ◽  
2014 ◽  
Vol 311 (5) ◽  
pp. 469 ◽  
Author(s):  
Jeffrey L. Saver
Keyword(s):  
Blood Pressure ◽  
Ischemic Stroke ◽  
Pressure Management ◽  
Blood Pressure Management

scholarly journals Individualized blood pressure management during endovascular treatment of acute ischemic stroke under procedural sedation (INDIVIDUATE) – An explorative randomized controlled trial

2021 ◽  
pp. 239698732110008
Author(s):  
Min Chen ◽  
Dorothea Kronsteiner ◽  
Markus A Möhlenbruch ◽  
Meinhard Kieser ◽  
Martin Bendszus ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Randomized Controlled Trial ◽  
Ischemic Stroke ◽  
Systolic Blood Pressure ◽  
Controlled Trial ◽  
Blood Pressure Target ◽  
Pressure Management ◽  
Randomized Controlled ◽  
Blood Pressure Management ◽  
Individualized Approach

Background Optimal blood pressure is not well established during endovascular therapy of acute ischemic stroke. Applying standardized blood pressure target values for every stroke patient might be a suboptimal approach. Aim To assess whether an individualized intraprocedural blood pressure management with individualized blood pressure target ranges might pose a better strategy for the outcome of the patients than standardized blood pressure targets. Sample size: Randomization of 250 patients 1:1 to receive either standard or individualized blood pressure management approach. Methods and design We conduct an explorative single-center randomized controlled trial with a PROBE (parallel-group, open-label randomized controlled trial with blinded endpoint evaluation) design. In the control group, intraprocedural systolic blood pressure target range is 140–180 mmHg. The intervention group is the individualized approach, which is maintaining the intraprocedural systolic blood pressure at the level on presentation (±10 mmHg). Study outcomes: The primary endpoint is the modified Rankin scale assessed 90 days +/− 2 weeks after stroke onset, dichotomized by 0–2 (favorable outcome) to 3–6 (unfavorable outcome). Secondary endpoints include early neurological improvement, infarction size, and systemic physiology monitor parameters. Discussion An individualized approach for blood pressure management during thrombectomy could lead to a better outcome for stroke patients. The trial is registered at clinicaltrials.gov as ‘Individualized Blood Pressure Management During Endovascular Stroke Treatment (INDIVIDUATE)’ under NCT04578288.

scholarly journals Management of Perioperative Target Blood Pressure in Bridging Therapy for Acute Ischemic Stroke

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Lin Zhu ◽  
Qinghong Wang ◽  
Cuncun Liu
Keyword(s):  
Blood Pressure ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Clinical Outcomes ◽  
Target Blood Pressure ◽  
Target Range ◽  
Pressure Management ◽  
Bridging Therapy ◽  
Clinical Prognosis ◽  
Blood Pressure Management

Abstract: Objective: To investigate the management of perioperative target blood pressure in the treatment of acute ischemic stroke with intravenous thrombolytic bridging. Methods: Retrospective analysis of the blood pressure management and nursing experience of 36 patients with acute ischemic stroke who received endovascular treatment with bridge mode from November 2017 to January 2019 in our hospital. Through correct monitoring of basic blood pressure, rapid and stable blood pressure reduction before the bridge treatment, close cooperation during the operation, and close observation and treatment of postoperative blood pressure fluctuations, the patient’s blood pressure can be controlled within the target range. Results: The blood vessels of 36 patients were partially or completely recanalized after treatment. Clinical outcomes: Two cases died. After 90 days, 29 patients with good clinical outcomes were followed up, and 5 patients with poor clinical prognosis. Conclusion: Effective blood pressure management is a necessary measure in the perioperative period of bridging therapy for patients with acute ischemic stroke, which can reduce the postoperative complications of patients treated with bridging therapy, obtain good therapeutic effect and improve the prognosis of patients.

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