Pharmacokinetics and bioequivalence of fixed-dose combination of candesartan cilexetil/amlodipine besylate (16/10 mg) versus coadministration of individual formulations in healthy subjects

Hae Won Lee; Woo Youl Kang; Wookjae Jung; Mi-Ri Gwon; Dong Heon Yang; Eun Hee Kim; Kyunghee Cho; Young-Ran Yoon; Sook Jin Seong

doi:10.12793/tcp.2020.28.e8

Pharmacokinetics and bioequivalence of fixed-dose combination of candesartan cilexetil/amlodipine besylate (16/10 mg) versus coadministration of individual formulations in healthy subjects

Translational and Clinical Pharmacology ◽

10.12793/tcp.2020.28.e8 ◽

2020 ◽

Vol 28 (2) ◽

pp. 92

Author(s):

Hae Won Lee ◽

Woo Youl Kang ◽

Wookjae Jung ◽

Mi-Ri Gwon ◽

Dong Heon Yang ◽

...

Keyword(s):

Healthy Subjects ◽

Candesartan Cilexetil ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Amlodipine Besylate ◽

Dose Combination

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Development and validation of an HPLC method using an experimental design for analysis of amlodipine besylate and enalapril maleate in a fixed dose combination

Turkish Journal of Pharmaceutical Sciences ◽

10.4274/tjps.galenos.2020.89725 ◽

2020 ◽

Vol 0 (0) ◽

pp. 0-0

Author(s):

Diren SARISALTIK-YASIN ◽

Alev ARSLANTURK-BINGUL ◽

Alptug KARAKUCUK ◽

Zeynep Safak TEKSIN

Keyword(s):

Experimental Design ◽

Hplc Method ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Amlodipine Besylate ◽

Enalapril Maleate ◽

Dose Combination ◽

Development And Validation

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Effect of food on the oral bioavailability of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide fixed dose combination tablets in healthy subjects

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.131 ◽

2014 ◽

Vol 3 (6) ◽

pp. 487-492 ◽

Cited By ~ 3

Author(s):

Gangadhar Sunkara ◽

Xuemin Jiang ◽

Christine Reynolds ◽

Denise Serra ◽

Yiming Zhang ◽

...

Keyword(s):

Oral Bioavailability ◽

Healthy Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Effect Of Food ◽

Dose Combination

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Pharmacokinetic Equivalence of the High Dose Strength Fixed-Dose Combination Tablet of Gemigliptin/Metformin Sustained Release (SR) and Individual Component Gemigliptin and Metformin XR Tablets in Healthy Subjects

Journal of Korean Medical Science ◽

10.3346/jkms.2018.33.e258 ◽

2018 ◽

Vol 33 (41) ◽

Author(s):

Yong-Soon Cho ◽

Shi Hyang Lee ◽

Hyeong-Seok Lim ◽

Kyun-Seop Bae

Keyword(s):

Sustained Release ◽

Healthy Subjects ◽

Individual Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

High Dose ◽

Combination Tablet ◽

Dose Combination

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Comparison of the Pharmacokinetics of Highly Variable Drugs in Healthy Subjects Using a Partial Replicated Crossover Study: A Fixed-Dose Combination of Fimasartan 120 mg and Atorvastatin 40 mg versus Separate Tablets

Drug Design Development and Therapy ◽

10.2147/dddt.s233732 ◽

2020 ◽

Vol Volume 14 ◽

pp. 1953-1961 ◽

Cited By ~ 1

Author(s):

Jungi Hwang ◽

Kyung-Sang Yu ◽

SeungHwan Lee

Keyword(s):

Crossover Study ◽

Healthy Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Highly Variable Drugs ◽

Dose Combination ◽

Separate Tablets

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Bioequivalence, Food Effect, and Steady‐State Assessment of Dapagliflozin/Metformin Extended‐release Fixed‐dose Combination Tablets Relative to Single‐component Dapagliflozin and Metformin Extended‐release Tablets in Healthy Subjects

Clinical Therapeutics ◽

10.1016/j.clinthera.2015.05.004 ◽

2015 ◽

Vol 37 (7) ◽

pp. 1517-1528 ◽

Cited By ~ 9

Author(s):

Ming Chang ◽

Xiaoni Liu ◽

Dapeng Cui ◽

Dan Liang ◽

Frank LaCreta ◽

...

Keyword(s):

Steady State ◽

Healthy Subjects ◽

Extended Release ◽

Food Effect ◽

State Assessment ◽

Single Component ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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Comparative effect of fixed-dose combination tablets of candesartan cilexetil/amlodipine versus olmesartan medoxomil/azelnidipine on laboratory parameters in patients with hypertension: a retrospective cohort study

Clinical and Experimental Hypertension ◽

10.3109/10641963.2015.1081214 ◽

2015 ◽

Vol 38 (2) ◽

pp. 173-179 ◽

Cited By ~ 4

Author(s):

Norio Susa ◽

Yayoi Nishida ◽

Yoichi Yada ◽

Tomohiro Nakayama ◽

Satoshi Asai ◽

...

Keyword(s):

Cohort Study ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Candesartan Cilexetil ◽

Olmesartan Medoxomil ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Comparative Effect ◽

Laboratory Parameters ◽

Dose Combination

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Pharmacokinetic and bioequivalence study comparing a candesartan cilexetil/rosuvastatin calcium fixed-dose combination with the concomitant administration of candesartan cilexetil and rosuvastatin calcium in healthy Korean subjects

International Journal of Clinical Pharmacology and Therapeutics ◽

10.5414/cp202740 ◽

2017 ◽

Vol 55 (03) ◽

pp. 286-294 ◽

Cited By ~ 2

Author(s):

Dan-Bee Park ◽

Kyungho Jang ◽

Jae-Won Lee ◽

Cheol-Won Park ◽

Back-Hwan Lee ◽

...

Keyword(s):

Candesartan Cilexetil ◽

Concomitant Administration ◽

Bioequivalence Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination ◽

Rosuvastatin Calcium

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Bioequivalence and food effect assessment for vildagliptin/metformin fixed-dose combination tablets relative to free combination of vildagliptin and metformin in Japanese healthy subjects

International Journal of Clinical Pharmacology and Therapeutics ◽

10.5414/cp202522 ◽

2016 ◽

Vol 54 (04) ◽

pp. 305-314

Author(s):

Sachiko Mita ◽

Shripad D. Chitnis ◽

Kenneth Kulmatycki ◽

Atish Salunke ◽

Yan-Ling He ◽

...

Keyword(s):

Healthy Subjects ◽

Food Effect ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Effect Assessment ◽

Dose Combination

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Bioequivalence of vildagliptin/metformin fixed-dose combination tablets and a free combination of vildagliptin and metformin in healthy subjects

International Journal of Clinical Pharmacology and Therapeutics ◽

10.5414/cpp46259 ◽

2008 ◽

Vol 46 (05) ◽

pp. 259-267 ◽

Cited By ~ 11

Author(s):

Y.-L. He ◽

S. Paladini ◽

H. Sabia ◽

J. Campestrini ◽

Y. Zhang ◽

...

Keyword(s):

Healthy Subjects ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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Bioequivalence Study of a Sustained Release Fixed Dose Combination Capsule Containing Esomeprazole and Domperidone in Healthy Subjects

Arzneimittelforschung ◽

10.1055/s-0031-1296618 ◽

2011 ◽

Vol 57 (05) ◽

pp. 274-277

Author(s):

Sangita Agarwal ◽

KadajjiVeeran Gowda ◽

Uttam Mandal ◽

Debotri Ghosh ◽

Anirbandeep Bose ◽

...

Keyword(s):

Sustained Release ◽

Healthy Subjects ◽

Bioequivalence Study ◽

Fixed Dose Combination ◽

Fixed Dose ◽

Dose Combination

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