Role of Prophylactic Thyroid Neck Dissection in Papillary Thyroid Cancer

2017 ◽  
Vol 69 (6) ◽  
pp. 2694-2697
Author(s):  
Hisham Sameer Alhathloul ◽  
Mohammed Ahmed Almasabi ◽  
Abdulghani Mohammad Lodhi
Keyword(s):  
Thyroid Cancer ◽  
Neck Dissection ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid

The role of prophylactic central compartment neck dissection in papillary thyroid cancer

2015 ◽  
Vol 87 (1) ◽  
pp. 41-48
Author(s):  
I. Koutelidakis ◽  
A. Doundis ◽  
G. Chatzimavroudis ◽  
J. Makris
Keyword(s):  
Thyroid Cancer ◽  
Neck Dissection ◽  
Papillary Thyroid Cancer ◽  
Central Compartment ◽  
Papillary Thyroid

scholarly journals Low transverse incision for lateral neck dissection in patients with papillary thyroid cancer: improved cosmesis

2017 ◽  
Vol 15 (1) ◽  
Author(s):  
Chang Myeon Song ◽  
Yong Bae Ji ◽  
In Sik Kim ◽  
Ji Young Lee ◽  
Dong Sun Kim ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Neck Dissection ◽  
Papillary Thyroid Cancer ◽  
Lateral Neck ◽  
Papillary Thyroid ◽  
Transverse Incision ◽  
Lateral Neck Dissection

The Role of Different Molecular Markers in Papillary Thyroid Cancer Patients with Acromegaly

2018 ◽  
Vol 127 (07) ◽  
pp. 437-444 ◽  
Author(s):  
Fatma Ela Keskin ◽  
Hande Mefkure Ozkaya ◽  
Sina Ferahman ◽  
Ozlem Haliloglu ◽  
Adem Karatas ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Ex Vivo ◽  
Papillary Thyroid ◽  
Cerrahpasa Medical Faculty ◽  
Protein Expressions ◽  
Galectin 3 ◽  
Benign Nodules ◽  
Igf1 Expression

Abstract Purpose Prevalence of papillary thyroid cancer (PTC) is increased in patients with acromegaly. We aimed to determine the protein expression of BRAF, RAS, RET, insulin like growth factor 1(IGF1), Galectine 3, CD56 in patients with PTC related acromegaly and to compare the extensity of these expressions with normal PTC patients and benign thyroid nodules. Methods We studied 313 patients with acromegaly followed in Cerrahpasa Medical Faculty, Endocrinology and Metabolism Clinic between 1998 and 2015. On the basis of availability of pathological specimen of thyroid tissues, thyroid samples of 13 patients from 19 with acromegaly related PTC (APTC), 20 normal PTC and 20 patients with multinodulary goiter (MNG) were histopathologically evaluated. Protein expressions were determined via immunohistochemical staining in ex-vivo tumor samples and benign nodules. Results The incidence of PTC in acromegaly patients were 6% (n=19). Among patients with PTC, APTC and MNG, all the immunohistochemical protein expressions we have studied were higher in papillary thyroid cancer groups (p<0.01, for all). Between PTC group without acromegaly and APTC, galectin 3 and IGF1 expression was significantly higher in acromegalic patients (p<0.01 for all) while RAS was predominantly higher in PTC patients without acromegaly (p<0.01). Conclusion BRAF expression was not higher in PTC with acromegaly patients compared to PTC patients without acromegaly. Galectine 3 and IGF1 were expressed more intensively in APTC. These positive protein expressions may have more influence on determining malign nodules among acromegaly patients.

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