scholarly journals Safety and efficacy of intravenous administration for tranexamic acid-induced emesis in dogs with accidental ingestion of foreign substances

2017 ◽  
Vol 79 (12) ◽  
pp. 1978-1982 ◽  
Author(s):  
Kensuke ORITO ◽  
Asako KAWARAI-SHIMAMURA ◽  
Atsushi OGAWA ◽  
Atsushi NAKAMURA
Keyword(s):  
Tranexamic Acid ◽  
Intravenous Administration ◽  
Accidental Ingestion ◽  
Safety And Efficacy

scholarly journals Safety and Efficacy of Intermittent Intravenous Administration of High-Dose Micafungin

2015 ◽  
Vol 61 (suppl_6) ◽  
pp. S652-S661 ◽  
Author(s):  
Dionysis Neofytos ◽  
Yao-Ting Huang ◽  
Kimberly Cheng ◽  
Nina Cohen ◽  
Miguel-Angel Perales ◽  
...  
Keyword(s):  
Intravenous Administration ◽  
High Dose ◽  
Safety And Efficacy

scholarly journals Topical vs. intravenous administration of tranexamic acid in knee arthroplasty and prevalence of deep venous thrombosis: a randomized clinical trial

2016 ◽  
Vol 15 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Ari Zekcer ◽  
Ricardo Del Priori ◽  
Clauber Tieppo ◽  
Ricardo Soares da Silva ◽  
Nilson Roberto Severino
Keyword(s):  
Total Knee Arthroplasty ◽  
Tranexamic Acid ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Intravenous Administration ◽  
Knee Arthroplasty ◽  
Duplex Ultrasound ◽  
Control Group ◽  
Perioperative Bleeding ◽  
Total Knee

Abstract Background Tranexamic acid (TXA) is widely used in orthopedic surgery to reduce perioperative bleeding. Since TXA inhibits fibrinolysis, there is concern that it may increase the risk of thromboembolic events. Objectives To verify the prevalence of deep venous thrombosis (DVT) in patients receiving TXA during total knee arthroplasty and to compare topical with intravenous administration of the drug. Methods All patients admitted for total knee arthroplasty due to primary arthrosis between June and November of 2014 were recruited consecutively. Thirty patients were randomized to a “topical group” (1.5 g TXA diluted in 50ml saline sprayed over the area operated, before tourniquet release), 30 to an “intravenous group” (20mg/kg TXA in 100 ml of saline, given at the same time as anesthesia), and 30 to a control group (100 ml of saline, given at the same time as anesthesia). All patients had duplex ultrasound scans of the legs on the 15th postoperative day. Results Deep venous thrombosis events occurred in five of the 90 patients operated (one out of 30 in the topical group [3.3%], four out of 30 in the control group [13.3%], and zero in the intravenous group). All were confirmed by duplex ultrasound scans and all were asymptomatic. Prevalence rates of DVT were similar between groups (p = 0.112 for control vs. intravenous; p = 0.353 for control vs. topical; and p =1.000 for intravenous vs. topical, according to two-sided exact tests). Conclusions Both topical and intravenous administration of TXA are safe with regard to occurrence of DVT, since the number of DVT cases in patients given TXA was not different to the number in those given placebo.

scholarly journals Safety and Efficacy of Caproamin Fides and Tranexamic Acid Versus Placebo in Patients Undergoing Coronary Artery Revascularization

2014 ◽  
Vol 6 (3) ◽  
pp. 197-202 ◽  
Author(s):  
Alireza Alizadeh Ghavidel ◽  
Ziae Totonchi ◽  
Mitra Chitsazan ◽  
Maziar Gholampour Dehaki ◽  
Farshid Jalili ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Tranexamic Acid ◽  
Safety And Efficacy ◽  
Coronary Artery Revascularization ◽  
Acid Versus

scholarly journals Safety and Efficacy of Intermittent Intravenous Administration of High-Dose Micafungin

2015 ◽  
Vol 2 (suppl_1) ◽  
Author(s):  
Dionysios Neofytos ◽  
Yao-Ting Huang ◽  
Kim Cheng ◽  
Nina Cohen ◽  
Miguel Perales ◽  
...  
Keyword(s):  
Intravenous Administration ◽  
High Dose ◽  
Safety And Efficacy

scholarly journals PDG78 SAFETY AND EFFICACY OF TRANEXAMIC ACID IN ADULT SPINAL DEFORMITY SURGERY: A META-ANALYSIS

2019 ◽  
Vol 22 ◽  
pp. S176
Author(s):  
D. Hariharan ◽  
M. Mammi ◽  
K. Daniels ◽  
K. Petrucci ◽  
N. Lamba ◽  
...  
Keyword(s):  
Tranexamic Acid ◽  
Spinal Deformity ◽  
Adult Spinal Deformity ◽  
Meta Analysis ◽  
Safety And Efficacy ◽  
Spinal Deformity Surgery

18. Safety and efficacy of tranexamic acid use in posterior cervical decompression and fusion surgery

2019 ◽  
Vol 19 (9) ◽  
pp. S9
Author(s):  
Joseph P. Gjolaj ◽  
Roberto J. Perez Roman ◽  
Karthik Madhavan ◽  
Julian Lugo-Pico
Keyword(s):  
Tranexamic Acid ◽  
Fusion Surgery ◽  
Safety And Efficacy

scholarly journals Comparison between topical and intravenous administration of tranexamic acid in primary total hip arthroplasty

2016 ◽  
Vol 21 (1) ◽  
pp. 44-47 ◽  
Author(s):  
Masaya Ueno ◽  
Motoki Sonohata ◽  
Norio Fukumori ◽  
Shunsuke Kawano ◽  
Masaru Kitajima ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Tranexamic Acid ◽  
Intravenous Administration ◽  
Hip Arthroplasty ◽  
Total Hip ◽  
Primary Total Hip Arthroplasty

Safety and Efficacy of Intra-articular Injection of Tranexamic Acid in Total Knee Arthroplasty

Orthopedics ◽  
2014 ◽  
Vol 37 (9) ◽  
pp. e775-e782 ◽  
Author(s):  
Yuan Zhang ◽  
Xin Fu ◽  
Wen-Xing Liu ◽  
Yao-Min Li ◽  
Xin-Long Ma ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Tranexamic Acid ◽  
Knee Arthroplasty ◽  
Safety And Efficacy ◽  
Total Knee
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