scholarly journals Effect of Intravenous Infusion of a 7.2% Hypertonic Saline Solution on Serum Electrolytes and Osmotic Pressure in Healthy Beagles.

1999 ◽  
Vol 61 (6) ◽  
pp. 637-641 ◽  
Author(s):  
Tadaharu AJITO ◽  
Kazuyuki SUZUKI ◽  
Shigehiro IWABUCHI
Keyword(s):  
Osmotic Pressure ◽  
Hypertonic Saline ◽  
Intravenous Infusion ◽  
Saline Solution ◽  
Serum Electrolytes ◽  
Hypertonic Saline Solution

Accidental Death Due to Erroneous Intravenous Infusion of Hypertonic Saline Solution for Hemodialysis

2004 ◽  
Vol 27 (9) ◽  
pp. 810-812 ◽  
Author(s):  
M. Di Paolo ◽  
M. Bruno ◽  
E. Sansoni ◽  
E. Gaggiotti ◽  
N. Di Paolo
Keyword(s):  
Hypertonic Saline ◽  
Intravenous Infusion ◽  
Saline Solution ◽  
Accidental Death ◽  
Hypertonic Saline Solution

scholarly journals Lidocaine coinfusion alleviates vascular pain induced by hypertonic saline infusion: a randomized, placebo-controlled trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhiping Song ◽  
Shibiao Chen ◽  
Yang Zhang ◽  
Xiaoyun Shi ◽  
Na Zhao ◽  
...  
Keyword(s):  
Hypertonic Saline ◽  
Saline Solution ◽  
Time Slot ◽  
Controlled Trial ◽  
Saline Infusion ◽  
Clinical Trial Registry ◽  
Hypertonic Saline Solution ◽  
Vas Scores ◽  
Vascular Pain ◽  
Hypertonic Saline Infusion

Abstract Background Hypertonic saline solution has been frequently utilized in clinical practice. However, due to the nonphysiological osmolality, hypertonic saline infusion usually induces local vascular pain. We conducted this study to evaluate the effect of lidocaine coinfusion for alleviating vascular pain induced by hypertonic saline. Methods One hundred and six patients undergoing hypertonic saline volume preloading prior to spinal anesthesia were randomly allocated to two groups of 53 each. Group L received a 1 mg/kg lidocaine bolus followed by infusion of 2 mg/kg/h through the same IV line during hypertonic saline infusion; Group C received a bolus and infusion of normal saline of equivalent volume. Visual analogue scale (VAS) scores of vascular pain were recorded every 4 min. Results The vascular pain severity in Group L was significantly lower than that in Group C for each time slot (P < 0.05). The overall incidence of vascular pain during hypertonic saline infusion in Group L was 48.0%, which was significantly lower than the incidence (79.6%) in Group C (P < 0.05). Conclusion Lidocaine coinfusion could effectively alleviate vascular pain induced by hypertonic saline infusion. Trial registration Chinese Clinical Trial Registry, number: ChiCTR1900023753. Registered on 10 June 2019.

scholarly journals Hypertonic Saline Solution Drives Neutrophil from Bystander Organ to Infectious Site in Polymicrobial Sepsis: A Cecal Ligation and Puncture Model

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e74369 ◽  
Author(s):  
Mariana Cardillo Theobaldo ◽  
Flavia Llimona ◽  
Ricardo Costa Petroni ◽  
Ester Correia Sarmento Rios ◽  
Irineu Tadeu Velasco ◽  
...  
Keyword(s):  
Hypertonic Saline ◽  
Saline Solution ◽  
Cecal Ligation ◽  
Polymicrobial Sepsis ◽  
Cecal Ligation And Puncture ◽  
Hypertonic Saline Solution ◽  
Puncture Model

scholarly journals Effects of the ice popsicle on vasopressin, osmolality, thirst intensity, and thirst discomfort

2021 ◽  
Vol 42 ◽  
Author(s):  
Thammy Gonçalves Nakaya ◽  
Marilia Ferrari Conchon ◽  
Aline Korki Arrabal Garcia ◽  
Ernane Torres Uchôa ◽  
Lígia Fahl Fonseca
Keyword(s):  
Hypertonic Saline ◽  
Statistical Difference ◽  
Saline Solution ◽  
Healthy Male ◽  
Hypertonic Saline Solution ◽  
Physiological Profile ◽  
Healthy Male Volunteers ◽  
Test Study ◽  
Post Test ◽  
Quasi Experimental

ABSTRACT Objective: To analyze the effects of the ice popsicle on vasopressin, osmolality, thirst intensity, and thirst discomfort. Method: This is a quasi-experimental, pre- and post-test study conducted in a laboratory. The sample consisted of nine healthy male volunteers, who received 2% hypertonic saline solution. Results: Popsicle intake did not result in a statistically significant reduction in vasopressin levels (F=0.876 and p=0.428). However, there was a reduction in the hormonal physiological profile of vasopressin from 7.1 pg/ml to 5.8 pg/ml after the first two interventions. Osmolality concentration changed from 270.65 to 286.51 mOsm/kg, with no statistical difference (F=2.207; p=0.09). Ice popsicles significantly reduced thirst intensity (F=10.00; p=0.001) and thirst discomfort (F=10.528; p <0.001). Conclusion: There was a reduction in thirst intensity and discomfort after the use of the 20 ml ice popsicle. There was no statistical difference for vasopressin and osmolality. However, there was a reduction in the hormonal physiological profile of vasopressin during 30 minutes of intervention.

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