Total intravenous anaesthesia

2021 ◽  
pp. 1-2
Author(s):  
Conor Jones ◽  
Joseph Harris
Keyword(s):  
Continuous Infusion ◽  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia ◽  
Effective Use

Advances in pharmacokinetic understanding have popularised the safe and effective use of total intravenous anaesthesia delivered by continuous infusion. This article explores why the practical and outcome benefits have made total intravenous anaesthesia an increasingly accepted alternative to use of inhalational agents.

Pharmacology and fluids

2019 ◽  
pp. 23-42
Author(s):  
Thomas Engelhardt
Keyword(s):  
Side Effects ◽  
Developmental Differences ◽  
Pharmacokinetic Parameters ◽  
Total Intravenous Anaesthesia ◽  
Small Children ◽  
Intravenous Anaesthesia ◽  
Anaesthetic Agents ◽  
Inhalational Anaesthetic ◽  
Intravenous Anaesthetic ◽  
Effective Use

Differences in pharmacokinetics and pharmacodynamics are important in small children. This chapter provides an overview of essential pharmacokinetic parameters and developmental aspects. Intravenous anaesthetic agents, including total intravenous anaesthesia models, are described. An overview of commonly used inhalational anaesthetic agents, sedatives, and neuromuscular blockers is given. The analgesic sections describe opioids, simple analgesics, and local anaesthetic agents. Paediatric indications, common side effects, and dosing are included for each agent. A fundamental understanding of developmental differences is key to the safe and effective use of anaesthetic drugs in children.

scholarly journals Total Intravenous Anaesthesia for Tracheobronchial Stenting in Children

2002 ◽  
Vol 30 (3) ◽  
pp. 376-379 ◽  
Author(s):  
M. Choudhury ◽  
N. Saxena
Keyword(s):  
Continuous Infusion ◽  
Tracheobronchial Tree ◽  
Rigid Bronchoscopy ◽  
Total Intravenous Anaesthesia ◽  
Cardiac Lesion ◽  
Intravenous Anaesthesia ◽  
Prolonged Intubation ◽  
Therapeutic Problem ◽  
Rapid Emergence ◽  
Cardiovascular Stability

Stenosis and malacia of the tracheobronchial tree, most often secondary to prolonged intubation, tracheostomy or following correction of a congenital cardiac lesion, present a significant therapeutic problem, especially when the lesions are extensive. The utilization of self-expanding tracheobronchial stents is a useful addition to the medical armamentarium for maintenance of airways in these patients with major airway stenosis and collapse. The majority of previous reported cases of tracheobronchial stenting have been performed under general anaesthesia with the help of rigid bronchoscopy under direct vision. We conducted two cases of tracheobronchial stenting in postoperative cardiosurgical babies under continuous propofol infusion taking advantage of cardiovascular stability during continuous infusion and rapid emergence after its discontinuation.

scholarly journals Midazolam-Flumazenil Topical Anaesthesia for Microlaryngoscopy with Jet Ventilation

1997 ◽  
Vol 25 (4) ◽  
pp. 358-364
Author(s):  
W. Rushatamukayanunt ◽  
T. Tritrakarn
Keyword(s):  
Treated Group ◽  
Muscle Relaxants ◽  
Total Intravenous Anaesthesia ◽  
Topical Anaesthesia ◽  
Parallel Study ◽  
Jet Ventilation ◽  
Double Blind ◽  
Intravenous Anaesthesia ◽  
Single Intravenous Injection ◽  
High Incidence

A comparison between midazolam and midazolam-flumazenil for total intravenous anaesthesia in combination with topical anaesthesia and muscle relaxants was performed in a double-blind, parallel study in 40 patients scheduled for microlaryngoscopy with or without bronchoscopic procedures using jet ventilation with oxygen. A single intravenous injection of midazolam 0.3 mg/kg, lignocaine spray and muscle relaxants provided adequate anaesthesia and good operative conditions throughout the procedures, which took 20 to 30 minutes. Patients who had placebo at the end of the procedures had a longer recovery and a high incidence of airway obstruction (20%). Administration of flumazenil provided prompt awakening in 19 of 20 patients (95%) within five minutes, resulting in rapid and favourable recovery without resedation or other side-effects, while only three of 20 (15%) patients in the placebo-treated group had improved consciousness within five minutes. The simplicity and reliability of the midazolam-flumazenil technique is attractive. We consider it worthy of further investigation for wider application in clinical practice.

Disoprofol (ICI 35868) for Total Intravenous Anaesthesia

1983 ◽  
Vol 27 (2) ◽  
pp. 113-116 ◽  
Author(s):  
R. J. Fragen ◽  
E. H. J. H. Hanssen ◽  
P. A. F. Denissen ◽  
L. H. D. J. Booij ◽  
J. F. Crui.
Keyword(s):  
Total Intravenous Anaesthesia ◽  
Intravenous Anaesthesia
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