Microscopic Stress Analysis by Multi-scale Computational Method at Crack Tip in Heterogeneous Media

2003 ◽  
Vol 2003.16 (0) ◽  
pp. 603-604 ◽  
Author(s):  
Yoshihiro OKUNO ◽  
Naoki TAKANO ◽  
Masaru ZAKO
2018 ◽  
Vol 784 ◽  
pp. 85-90
Author(s):  
Stanislav Seitl ◽  
Petr Miarka ◽  
Ildikó Merta ◽  
Zbyněk Keršner

Wedge-splitting test is widely used fracture mechanical test for its stability in measurement during the testing and many papers were published. However, the biaxial wedge-splitting test is relatively a new method and the numerical stress analysis of such test is necessary. Especially the investigation of the stress fields in the vicinity of the crack tip. In this contribution, influence of various biaxial stress level is discussed on values of first and second terms of William’s expansion.


2011 ◽  
Vol 02 (08) ◽  
pp. 1027-1032
Author(s):  
George A. Papadopoulos ◽  
Elen B. Bouloukou ◽  
Elen G. Papadopoulou

BioTechniques ◽  
2020 ◽  
Vol 69 (1) ◽  
pp. 18-25
Author(s):  
Hongqiang Lyu ◽  
Lin Li ◽  
Zhifang Wu ◽  
Tian Wang ◽  
Jiguang Zheng ◽  
...  

A topologically associated domain (TAD) is a self-interacting genomic block. Detection of TAD boundaries on Hi-C contact matrix is one of the most important issues in the analysis of 3D genome architecture at TAD level. Here, we present TAD boundary detection (TADBD), a sensitive and fast computational method for detection of TAD boundaries on Hi-C contact matrix. This method implements a Haar-based algorithm by considering Haar diagonal template, acceleration via a compact integrogram, multi-scale aggregation at template size and statistical filtering. In most cases, comparison results from simulated and experimental data show that TADBD outperforms the other five methods. In addition, a new R package for TADBD is freely available online.


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