2011 Three-Dimensional Simulation of Red Blood Cell Motion under Simple Shear Flow Using Particle Method

2010 ◽  
Vol 2010.23 (0) ◽  
pp. 22-23
Author(s):  
Ken-ichi TSUBOTA ◽  
Shigeo WADA ◽  
Hao LIU
1995 ◽  
Vol 283 ◽  
pp. 175-200 ◽  
Author(s):  
Hua Zhou ◽  
C. Pozrikidis

The transient deformation of liquid capsules enclosed by incompressible membranes whose mechanical properties are dominated by isotropic tension is studied as a model of red blood cell deformation in simple shear flow. The problem is formulated in terms of an integral equation for the distribution of the tension over the cell membrane which is solved using a point-wise collocation and a spectral-projection method. The computations illustrate the dependence of the deformed steady cell shape, membrane tank-treading frequency, membrane tension, and rheological properties of a dilute suspension, on the undeformed cell shape. The general features of the evolution of two-dimensional cells are found to be similar to those of three-dimensional cells, and the corresponding membrane tank-treading frequency and maximum tension are seen to attain comparable values. The numerical results are compared with previous asymptotic analyses for small deformations and available experimental observations, with satisfactory agreement. An estimate of the maximum shear stress for membrane breakup and red blood cell hemolysis is deduced on the basis of the computed maximum membrane tension at steady state.


Author(s):  
Toshihiro OMORI ◽  
Takuji ISHIKAWA ◽  
Yohsuke IMAI ◽  
Takami YAMAGUCHI

Author(s):  
Toshihiro OMORI ◽  
Takuji ISHIKAWA ◽  
Dominique BARTHES-BIESEL ◽  
Yohsuke IMAI ◽  
Takami YAMAGUCHI

Author(s):  
Toshihiro OMORI ◽  
Takuji ISHIKAWA ◽  
Dominique BARTHES-BIESEL ◽  
Yohsuke IMAI ◽  
Takami YAMAGUCHI

1998 ◽  
Vol 10 (8) ◽  
pp. 1834-1845 ◽  
Author(s):  
C. D. Eggleton ◽  
A. S. Popel

2012 ◽  
Vol 86 (5) ◽  
Author(s):  
T. Omori ◽  
T. Ishikawa ◽  
D. Barthès-Biesel ◽  
A.-V. Salsac ◽  
Y. Imai ◽  
...  

2014 ◽  
Vol 34 ◽  
pp. 1460373
Author(s):  
TING YE ◽  
NHAN PHAN-THIEN ◽  
BOO CHEONG KHOO ◽  
CHWEE TECK LIM

The present work reports an attempt to apply the dissipative particle dynamics (DPD) method to study the dynamic behaviors of a red blood cell (RBC) in simple shear flow. The simulation system is discretized into four types of particles, namely wall particles, fluid particles, membrane particles and internal particles. The particle interaction is modeled by the DPD method, and the membrane particles are connected into a viscoelastic triangular network to represent the RBC membrane. As benchmarking tests, we simulate the deformation of a spherical capsule in shear flow and compare it with the past study, and also examine the effect of computational domain size. After that, we investigate the dynamics of a RBC in shear flow at different membrane shear and bending moduli. Our simulations reproduce the tank-treading, trembling and tumbling motions of the RBC at the shear modulus Es = 6, 60 and 600 μN/m, respectively. Moreover, we find that the RBC undergoes a trembling motion when its bending modulus is large enough, where the obvious stretching and smoothing of the RBC occur alternately in shape.


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