This paper presents a rational method by which an effective random vibration screen may be developed efficiently and quantitatively. In summary, a Flaw Precipitation Threshold (FPT) was derived from measurements of vibration response at known flaw locations. Responses were measured on a variety of modern electronic and electro-mechanical equipment, manufactured by five different manufacturers, during ongoing vibration screens. A vibration screen can be tailored for a piece of equipment by performing a global vibration response survey and adjusting the input spectra so that the response falls within the FPT.