Relationship Between Changes in Biochemical Markers of Bone Turnover and BMD to Predict Vertebral Fracture Risk

2003 ◽  
Vol 19 (3) ◽  
pp. 394-401 ◽  
Author(s):  
Somnath Sarkar ◽  
Jean-Yves Reginster ◽  
Gerald G Crans ◽  
Adolfo Diez-Perez ◽  
Karen V Pinette ◽  
...  
Keyword(s):  
Vertebral Fracture ◽  
Bone Turnover ◽  
Fracture Risk ◽  
Biochemical Markers ◽  
Vertebral Fracture Risk ◽  
Markers Of Bone Turnover

Interest of biochemical markers of bone turnover for long-term prediction of new vertebral fracture in postmenopausal osteoporotic women

Maturitas ◽  
2003 ◽  
Vol 44 (4) ◽  
pp. 259-265 ◽  
Author(s):  
Olivier Bruyere ◽  
Julien Collette ◽  
Pierre Delmas ◽  
Alain Rouillon ◽  
Christian Roux ◽  
...  
Keyword(s):  
Vertebral Fracture ◽  
Bone Turnover ◽  
Biochemical Markers ◽  
Term Prediction ◽  
Markers Of Bone Turnover ◽  
Long Term Prediction

Biochemical Markers of Bone Turnover and Fracture Prediction

2003 ◽  
Vol 9 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Rosemary A Hannon ◽  
Richard Eastell
Keyword(s):  
Bone Mineral Density ◽  
Bone Resorption ◽  
Bone Turnover ◽  
Fracture Risk ◽  
Bone Mineral ◽  
Biochemical Markers ◽  
Mineral Density ◽  
Risk Of Fracture ◽  
Increased Risk ◽  
Markers Of Bone Turnover

Low bone mineral density is a strong risk factor for fractures in the older woman. Biochemical markers of bone turnover may predict fracture risk independently of bone mineral density. High levels of bone resorption markers are associated with increased risk of fracture in both retrospective and prospective studies, although the evidence for bone formation markers and fracture risk is equivocal. For example, the risk of fracture is increased up to two-fold in women with elevated levels of several markers of bone resorption. Prediction models have been developed to predict the 10–year risk of fracture using bone mineral density and biochemical markers of bone turnover and these could prove very useful in clinical practice.

Sign in / Sign up

Export Citation Format

Share Document