Temporal and spatial response properties of optic neuritis patients manifesting statokinetic dissociation

1991 ◽  
Vol 30 (16) ◽  
pp. 2136 ◽  
Author(s):  
Evanne J. Casson ◽  
Masahiro Osako ◽  
Chris A. Johnson ◽  
Peter Hwang
2020 ◽  
Vol 4 (3) ◽  
pp. 852-870
Author(s):  
Jannik Luboeinski ◽  
Tatjana Tchumatchenko

Optogenetic stimulation has become the method of choice for investigating neural computation in populations of neurons. Optogenetic experiments often aim to elicit a network response by stimulating specific groups of neurons. However, this is complicated by the fact that optogenetic stimulation is nonlinear, more light does not always equal to more spikes, and neurons that are not directly but indirectly stimulated could have a major impact on how networks respond to optogenetic stimulation. To clarify how optogenetic excitation of some neurons alters the network dynamics, we studied the temporal and spatial response of individual neurons and recurrent neural networks. In individual neurons, we find that neurons show a monotonic, saturating rate response to increasing light intensity and a nonmonotonic rate response to increasing pulse frequency. At the network level, we find that Gaussian light beams elicit spatial firing rate responses that are substantially broader than the stimulus profile. In summary, our analysis and our network simulation code allow us to predict the outcome of an optogenetic experiment and to assess whether the observed effects can be attributed to direct or indirect stimulation of neurons.


1987 ◽  
Vol 44 (9) ◽  
pp. 1669-1673 ◽  
Author(s):  
Kurt W. Pontasch ◽  
Merlyn A. Brusven

A post-impact study on a 94438-L unleaded gasoline spill into Wolf Lodge Creek in northern Idaho was undertaken to determine the temporal and spatial response of periphyton following the spill. Periphytic biomass and chlorophyll a concentrations were determined above and below the spill. Downstream areas were mechanically agitated to release substrate-trapped hydrocarbons 35 d after the spill. Periphyton samples taken 26 d after the spill indicated that periphytic biomass, especially of the heterotrophs, was greater in the impacted than unimpacted areas; the Autorophic Index was up to 30 times greater in the impacted reach. Two months after the spill and 1 mo after stream cleaning, the Autotrophic Index was approximately the same in reference and impacted areas.


2005 ◽  
Vol 50 (5) ◽  
pp. 1687-1696 ◽  
Author(s):  
Robert M. Morris ◽  
Kevin L. Vergin ◽  
Jang-Cheon Cho ◽  
Michael S. Rappé ◽  
Craig A. Carlson ◽  
...  

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