Advances in optical imaging of dynamic three-dimensional engineered tissues

2006 ◽  
Author(s):  
Stephen A. Boppart ◽  
Claudio Vinegoni ◽  
Wei Tan ◽  
Wei Luo ◽  
Tyler S. Ralston ◽  
...  
Author(s):  
Wei Tan ◽  
Lester J. Fahrner ◽  
Aylin Sendemir-Urkmez ◽  
Russell D. Jamison ◽  
Deborah E. Leckband ◽  
...  

The Prostate ◽  
2021 ◽  
Author(s):  
Stefano Cipollari ◽  
Neema Jamshidi ◽  
Liutao Du ◽  
Kyunghyun Sung ◽  
Danshan Huang ◽  
...  

2007 ◽  
Vol 90 (13) ◽  
pp. 131101 ◽  
Author(s):  
E. Ramsay ◽  
K. A. Serrels ◽  
M. J. Thomson ◽  
A. J. Waddie ◽  
M. R. Taghizadeh ◽  
...  

Author(s):  
Alicja Jagiello ◽  
Qingda Hu ◽  
Ulysses Castillo ◽  
Elliot Botvinick

2020 ◽  
Vol 7 (5) ◽  
pp. 471-482
Author(s):  
Jean-Daniel Malcor ◽  
Emma J Hunter ◽  
Natalia Davidenko ◽  
Daniel V Bax ◽  
Ruth Cameron ◽  
...  

Abstract Porous biomaterials which provide a structural and biological support for cells have immense potential in tissue engineering and cell-based therapies for tissue repair. Collagen biomaterials that can host endothelial cells represent promising tools for the vascularization of engineered tissues. Three-dimensional collagen scaffolds possessing controlled architecture and mechanical stiffness are obtained through freeze–drying of collagen suspensions, followed by chemical cross-linking which maintains their stability. However, cross-linking scaffolds renders their biological activity suboptimal for many cell types, including human umbilical vein endothelial cells (HUVECs), by inhibiting cell–collagen interactions. Here, we have improved crucial HUVEC interactions with such cross-linked collagen biomaterials by covalently coupling combinations of triple-helical peptides (THPs). These are ligands for collagen-binding cell-surface receptors (integrins or discoidin domain receptors) or secreted proteins (SPARC and von Willebrand factor). THPs enhanced HUVEC adhesion, spreading and proliferation on 2D collagen films. THPs grafted to 3D-cross-linked collagen scaffolds promoted cell survival over seven days. This study demonstrates that THP-functionalized collagen scaffolds are promising candidates for hosting endothelial cells with potential for the production of vascularized engineered tissues in regenerative medicine applications.


2019 ◽  
Vol 108 (4) ◽  
pp. 1065-1071 ◽  
Author(s):  
Jordan S. Taylor ◽  
Sriraman Madhavan ◽  
Dalia Szafer ◽  
Allison Pei ◽  
Rajashree Koppolu ◽  
...  

2015 ◽  
Vol 20 (12) ◽  
pp. 121311 ◽  
Author(s):  
Erbao Dong ◽  
Zuhua Zhao ◽  
Minjie Wang ◽  
Yanjun Xie ◽  
Shidi Li ◽  
...  

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