scholarly journals Reasoning, Learning, and Creativity: Frontal Lobe Function and Human Decision-Making

PLoS Biology ◽  
2012 ◽  
Vol 10 (3) ◽  
pp. e1001293 ◽  
Author(s):  
Anne Collins ◽  
Etienne Koechlin
1993 ◽  
Vol 73 (2) ◽  
pp. 615-621 ◽  
Author(s):  
Anneliese A. Pontius

Proust detailed inexplicable behavior long before the neurobiologists Goddard and McIntyre in 1972 demonstrated that intermittent repetition of harmless stimuli can cause “kindling” of a seizure (with or without motor convulsions). Such brief seizures can occur especially in the evolutionarily old limbic system which mediates basic drives, their concomitant emotions, and certain aspects of memory. It appears that in humans the influence of specific external stimuli that revive the memory of repeated past experiences may “kindle” a transient episode of limbic overactivation. Thereupon the normal balance between the limbic and frontal lobe systems is disturbed (for a few minutes) as are normal human decision making and control of action. Linked with such a transient frontolimbic imbalance is out-of-character behavior, psychosis (hallucinations or delusions), autonomic activation, and severe distortion of affect and of action, culminating in extreme cases in a “Limbic Psychotic Trigger Reaction,” as proposed by Pontius in 1981, in motiveless homicidal acts with mostly preserved consciousness and memory for the acts.


2016 ◽  
Vol 14 (1) ◽  
pp. 41-47
Author(s):  
Ayumi Yoshioka ◽  
Shiro Shiwa ◽  
Takahiro Osumi ◽  
Hiroki C. Tanabe

2013 ◽  
Author(s):  
Scott D. Brown ◽  
Pete Cassey ◽  
Andrew Heathcote ◽  
Roger Ratcliff

2013 ◽  
Author(s):  
Laurence T. Maloney ◽  
James Tee ◽  
Hang Zhang

2019 ◽  
Vol 63 (1) ◽  
pp. 105-116
Author(s):  
Mark W. Hamilton

Abstract The dual endings of Hosea promoted reflection on Israel’s history as the movement from destruction to restoration based on Yhwh’s gracious decision for Israel. It thus clarifies the endings of the prior sections of the book (chs. 3 and 11) by locating Israel’s future in the realm of Yhwh’s activities. The final ending (14:10) balances the theme of divine agency in 14:2–9 with the recognition of human decision-making and moral formation as aspects of history as well. The endings of Hosea thus offer a good example of metahistoriography, a text that uses non-historiographic techniques to speak of the movements of history.


2012 ◽  
Author(s):  
Paolo Grigolini ◽  
Bruce J. West

2021 ◽  
Vol 10 (13) ◽  
pp. 2779
Author(s):  
Sang-Hwa Lee ◽  
Yeonkyeong Lee ◽  
Minji Song ◽  
Jae Jun Lee ◽  
Jong-Hee Sohn

Neuroimaging and neuropsychological investigations have indicated that migraineurs exhibit frontal lobe-related cognitive impairment. We investigated whether orbitofrontal and dorsolateral functioning differed between individuals with episodic migraine (EM) and chronic migraine (CM), focusing on orbitofrontal dysfunction because it is implicated in migraine chronification and medication overuse headache (MOH) in migraineurs. This cross-sectional study recruited women with CM with/without MOH (CM + MOH, CM − MOH), EM, and control participants who were matched in terms of age and education. We conducted neuropsychological assessments of frontal lobe function via the Trail Making Test (TMT) A and B, the Wisconsin Card Sorting Test (WCST), and the Iowa Gambling Task (IGT). We enrolled 36 CM (19 CM + MOH, 17 CM–MOH), 30 EM, and 30 control participants. The CM patients performed significantly (p < 0.01) worse on the TMT A and B than the EM patients and the control participants. The WCST also revealed significant differences, with poorer performance in the CM patients versus the EM patients and the control participants. However, the net scores on the IGT did not significantly differ among the three groups. Our findings suggest that the CM patients exhibited frontal lobe dysfunction, and, particularly, dorsolateral dysfunction. However, we found no differences in frontal lobe function according to the presence or absence of MOH.


Author(s):  
Nelson Mauro Maldonato ◽  
Alessandro Chiodi ◽  
Donatella di Corrado ◽  
Antonietta M. Esposito ◽  
Salvatore de Lucia ◽  
...  

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